中国全科医学 ›› 2022, Vol. 25 ›› Issue (13): 1551-1556.DOI: 10.12114/j.issn.1007-9572.2022.0077

所属专题: 社区卫生服务最新研究合集 老年人群健康最新文章合集 安全用药最新文章合集 老年人合理用药专题研究 老年问题最新文章合集

• 老年人合理用药专题研究 • 上一篇    下一篇

社区老年人潜在不适当用药及其应对模式的研究进展

王思蒙1, 张晨2, 孙雪1, 王丽娜1,*()   

  1. 1.313000 浙江省湖州市,湖州师范学院医学院
    2.313001 浙江省湖州市,滨湖街道社区卫生服务中心公卫科
  • 收稿日期:2022-01-28 修回日期:2022-04-01 出版日期:2022-04-12 发布日期:2022-04-22
  • 通讯作者: 王丽娜
  • 王思蒙,张晨,孙雪,等.社区老年人潜在不适当用药及其应对模式的研究进展[J].中国全科医学,2022,25(13):1551-1556.[www.chinagp.net]
    作者贡献:王丽娜负责文章构思、设计及文稿修改;王思蒙负责文章构思、设计、论文撰写及修改;张晨负责文章的修改;孙雪负责文献/资料的收集与整理。
  • 基金资助:
    国家自然科学基金资助项目(72174061)——运动认知功能减退综合征分类预测及高危人群"分型匹配-路径导向式"风险管理模式的构建及评价; 浙江省大学生科技创新活动计划暨新苗人才计划(2021R431031)——社区老年人群运动认知功能减退综合征归因体系及归因路径研究; 浙江省卫生健康科技计划(2022KY370)——社区老年人群运动认知功能减退综合征归因机制研究及风险管理策略的构建

Latest Advances in Coping Modes for Potentially Inappropriate Medications in Older Adults

Simeng WANG1, Chen ZHANG2, Xue SUN1, Lina WANG1,*()   

  1. 1. School of Medicine, Huzhou University, Huzhou 313000, China
    2. Department of Public Health, Binhu Subdistrict Community Health Center, Huzhou 313001, China
  • Received:2022-01-28 Revised:2022-04-01 Published:2022-04-12 Online:2022-04-22
  • Contact: Lina WANG
  • About author:
    WANG S M, ZHANG C, SUN X, et al. Latest advances in coping modes for potentially inappropriate medications in older adults[J]. Chinese General Practice, 2022, 25 (13) : 1551-1556.

摘要: 老年人常罹患多种慢性病并需要同时接受多种药物治疗,在药物代谢动力学和药物效应动力学改变的背景下,易发生潜在不适当用药(PIM)的情况。老年人PIM的发生率较高,PIM可增加老年人衰弱、跌倒、认知功能衰退等不良事件的发生风险,但目前我国对老年人PIM的研究较为薄弱,且在基层医疗环境下老年人PIM问题尚未得到充分重视,缺乏规范化、智能化的管理手段。本文通过对国内外老年人PIM的现状、筛查与评估工具及应对模式进行综述,旨在为减少PIM对老年人造成的危害、规范药品管理提供理论支持与实践借鉴。

关键词: 老年人, 潜在不适当用药, 应对模式, 综述

Abstract:

Due to susceptibility to multiple chronic diseases, polypharmacy is often needed in older adults, which may easily lead to increased risk of potentially inappropriate medications (PIM) if polypharmacy is accompanied by various alterations in pharmacokinetics and pharmacodynamics of medications. PIM are highly prevalent in older adults, which may be asociated with higher risks of frailty, falls, cognitive decline, and other adverse drug events. In China, the research on PIM is relatively weak, and PIM are insufficiently focused and often managed with non-standardized and non-intelligent approaches in primary care. We systematically reviewed recent studies in the prevalence, screening and assessment tools and management strategies of PIM in older adults, providing theoretical support and practical reference for reducing the harm of PIM and standardizing drug management.

Key words: Elderly, Potentially inappropriate medications, Cope mode, Review