关键词: 高血压, 脑梗死, 斑块, 动脉粥样硬化, 易损斑块, 颈动脉

Abstract: Objective　To observe the predilection site and acoustic characteristics of carotid artery vulnerable plaques in hypertension complicated with cerebral infarction patients and to explore the value of velocity vector imaging（VVI） technology to detect the stress and strain of plaques.Methods　98 patients in hypertension complicated with carotid artery atherosclerotic plaques with cerebral infarction（as case group） and 70 patients in hypertension associated with carotid artery atherosclerotic plaques（as control group） were chosen from May 2016 to June 2017 in North China University of Science and Technology Affiliated Hospital.The location of the vulnerable plaques were observed by two-dimensional ultrasound，and the main mechanical parameters of carotid arterial wall and plaques including velocity，strain and strain rate were detected by VVI technology.Results　There were 88 cases（52.4%） of carotid bifurcation plaques of patients of two groups，mainly to vulnerable plaques.And the incidence of vulnerable plaques of the common carotid artery was 17.8%（30/168），and the extracranial segment of internal carotid artery was 29.8%（50/168）．In the case group，50 cases（51.0%） had hypoechoic plaques，48 cases（49.0%） had heterogeneous plaques.And in the control group，38 cases（54.3%） had hypoechoic plaques，32 cases（45.7%） had heterogeneous plaques.There were no significant difference in the distributions of the hypoechoic plaques and the heterogeneous plaques between two groups（P>0.05）．The velocity，plaque strain and strain rate in the proximal intimal surface，proximal shoulder，the top of plaques，distal shoulder and distal intimal surface of the hypoechoic plaques and the heterogeneous plaques in case group were higher than those in control group（P<0.05）．Conclusion　The stability of carotid artery vulnerable plaques in hypertension complicated with cerebral infarction patients is worse than that in patients with hypertension，and the mechanical changes of carotid arterial plaques by VVI technology can provide an objective basis for early prevention and treatment of hypertension and for reducing recurrence rate of cerebral infarction.

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