中国全科医学 ›› 2023, Vol. 26 ›› Issue (09): 1044-1052.DOI: 10.12114/j.issn.1007-9572.2022.0709

所属专题: 运动相关研究最新文章合集 中医最新文章合集

• 论著·非特异性腰痛 • 上一篇    下一篇

运动针法可有效提高急性非特异性腰痛有效性:一项Meta分析

费静雯, 林蕙泽, 张萍萍, 柳兰萍, 王翔, 申江红, 朱可欣, 杨涛*(), 于金娜*()   

  1. 100053 北京市,中国中医科学院广安门医院针灸科
  • 收稿日期:2022-07-16 修回日期:2022-12-09 出版日期:2023-03-20 发布日期:2022-12-29
  • 通讯作者: 杨涛, 于金娜

  • 作者贡献:费静雯进行文章的构思与研究的设计,负责文献/资料整理、撰写论文;林蕙泽、张萍萍、柳兰萍、王翔、申江红、朱可欣进行文献/资料收集;林蕙泽负责英文的修订;杨涛、于金娜对文章整体负责,监督管理;于金娜负责研究的可行性分析、文章质量控制和审校。
  • 基金资助:
    国家重点研发计划项目(2019YFC1712200)

Motion Style Acupuncture Can Effectively Improve the Effectiveness of Acute Nonspecific Low Back Pain: a Meta-analysis

FEI Jingwen, LIN Huize, ZHANG Pingping, LIU Lanping, WANG Xiang, SHEN Jianghong, ZHU Kexin, YANG Tao*(), YU Jinna*()   

  1. Department of Acupuncture, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China
  • Received:2022-07-16 Revised:2022-12-09 Published:2023-03-20 Online:2022-12-29
  • Contact: YANG Tao, YU Jinna

摘要: 背景 近年陆续出现了多项运动针法治疗急性非特异性腰痛(ANSLBP)的随机对照试验(RCTs),但尚缺乏新的关于运动针法治疗ANSLBP有效性和安全性的系统评价。 目的 通过Meta分析方法系统评价运动针法治疗ANSLBP的有效性和安全性。 方法 计算机检索中国知网(CNKI)、中国生物医学文献数据库(CBM)、万方数据知识服务平台(Wanfang Data)、维普网(VIP)、PubMed、the National Library of Medicine(MEDLINE)、Embase、the Cochrane Central Register of Controlled Trials(CENTRAL),筛选运动针法治疗ANSLBP有效性和安全性的RCTs、交叉研究、队列研究,检索时间为数据库建立至2021-03-25。采用Revman 5.3软件完成Meta分析。 结果 最终纳入的17篇文献研究类型均为RCTs,共涉及1 226例患者,其中观察组610例,采用运动针法治疗;对照组616例,采用阳性对照或空白对照/安慰针/假针。Meta分析结果:(1)运动针法对照西药,观察组患者治疗后视觉模拟评分法(VAS)评分〔MD=-1.54,95%CI(-2.43,-0.65),P=0.000 7〕、Roland-Morris腰椎功能障碍调查表(RMDQ)评分〔MD=-3.08,95%CI(-4.92,-1.24),P=0.001〕低于对照组,腰椎关节活动度(ROM)大于对照组〔MD=-1.42,95%CI(-1.62,-1.22),P<0.000 01〕,总有效率高于对照组〔RR=1.27,95%CI(1.19,1.35),P<0.000 01〕,但两组患者治疗后Oswestry功能障碍指数(ODI)评分比较,差异无统计学意义〔MD=-5.11,95%CI(-19.12,8.91),P=0.48〕;(2)运动针法对照假针,观察组患者治疗后VAS评分〔MD=-1.70,95%CI(-2.05,-1.35),P<0.000 01〕、RMDQ评分〔MD=-3.06,95%CI(-4.50,-2.70),P<0.000 01〕低于对照组;(3)运动针法对照物理治疗,观察组患者治疗后VAS评分〔MD=-1.60,95%CI(-2.06,-1.14),P<0.000 01〕、RMDQ评分〔MD=-3.00,95%CI(-4.31,-1.69),P<0.000 01〕低于对照组;(4)运动针法对照推拿,观察组患者治疗后VAS评分低于对照组〔MD=-1.50,95%CI(-1.65,-1.35),P<0.000 01〕,总有效率高于对照组〔RR=1.19,95%CI(1.09,1.30),P=0.000 1〕。1篇文献报道观察组患者治疗期间不良事件发生率为13.33%(4/30)。 结论 现有文献证据表明运动针法能有效减轻ANSLBP患者疼痛、腰椎功能障碍,提高患者腰椎ROM及总有效率,且安全性较高,但仍需更多大样本、高质量RCTs进一步证实。

关键词: 腰痛, 针刺疗法, 急性非特异性腰痛, 运动针法, 治疗结果, 中医药疗法, 随机对照试验, Meta分析

Abstract:

Background

Many randomized controlled trials (RCTs) about motion style acupuncture in the treatment of acute nonspecific low back pain (ANSLBP) have been published recently, but there is no new systematic evaluation for effectiveness and safety of this treatment in ANSLBP.

Objective

To systematically evaluate the effectiveness and safety of motion style acupuncture in treating ANSLBP by meta-analysis.

Methods

RCTs, crossover studies or cohort studies about effectiveness and safety of motion style acupuncture in treating ANSLBP were retrieved in electronic databases of CNKI, CBM, Wanfang Data, VIP, PubMed, the National Library of Medicine, Embase and the Cochrane Central Register of Controlled Trials from inception to March 25th, 2021. Revman 5.3 was used to complete the Meta-analysis.

Results

All the finally enrolled 17 articles used a design of RCT, including 1 226 patients, and 610 of them were treated with motion style acupuncture (observation group) , and other 616 patients were treated with positive control, blank control, placebo acupuncture or dummy acupuncture (control group) . Meta-analysis showed that, compared with controls treated with Western medicine, the observation group had significantly lower post-treatment VAS score〔MD=-1.54, 95%CI (-2.43, -0.65) , P=0.000 7〕, and Roland-Morris Disability Questionnaire (RMDQ) score〔MD=-3.08, 95%CI (-4.92, -1.24) , P=0.001〕, and significantly higher post-treatment ROM of lumbar vertebra〔MD=-1.42, 95%CI (-1.62, -1.22) , P<0.000 01〕and overall response rate〔RR=1.27, 95%CI (1.19, 1.35) , P<0.000 01〕, but there was no significant difference in post-treatment ODI score between the two groups〔MD=-5.11, 95%CI (-19.12, 8.91) , P=0.48〕. Compared with controls treated with dummy acupuncture, the observation group had significantly lower post-treatment VAS score〔MD=-1.70, 95%CI (-2.05, -1.35) , P<0.000 01〕and RMDQ score〔MD=-3.06, 95%CI (-4.50, -2.70) , P<0.000 01〕. Compared with controls treated with physical therapy, the observation group had significantly lower post-treatment VAS score〔MD=-1.60, 95%CI (-2.06, -1.14) , P<0.000 01〕and RMDQ score〔MD=-3.00, 95%CI (-4.31, -1.69) , P<0.000 01〕. Compared with controls treated with Tuina, the observation group had significantly lower post-treatment VAS score〔MD=-1.50, 95%CI (-1.65, -1.35) , P<0.000 01〕, and significantly higher overall response rate〔RR=1.19, 95%CI (1.09, 1.30) , P=0.000 1〕. Only one RCT reported that the incidence of adverse events in observation group was 13.33% (4/30) during treatment.

Conclusion

Available documentary evidence showed that, motion style acupuncture can effectively relieve the pain and lumbar dysfunction, and improve the ROM of lumbar vertebra and overall response rate in patients with ANSLBP, with high safety, but which still needs to be confirmed by more high-quality, large-sample RCTs.

Key words: Lumbago, Acupuncture therapy, Acute nonspecific low back pain, Motion style acupuncture therapy, Treatment outcome, Traditional Chinese medicine therapy, Randomized controlled trial, Meta-analysis