Chinese General Practice ›› 2023, Vol. 26 ›› Issue (02): 241-247.DOI: 10.12114/j.issn.1007-9572.2022.0567
Special Issue: 老年问题最新文章合集
• Medication Guide·Precision Medication • Previous Articles Next Articles
Received:
2022-09-03
Revised:
2022-10-12
Published:
2023-01-15
Online:
2022-10-27
Contact:
SONG Pingan
About author:
通讯作者:
宋平安
作者简介:
基金资助:
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2022.0567
Figure 1 Waterfall plot for the best percentage change in target lesion size of the 63 elderly patients with non-small cell lung cancer who received PD-1 inhibitors
变量 | B | SE | Wald χ2值 | P值 | HR(95%CI) |
---|---|---|---|---|---|
年龄 | -0.112 | 2.45 | 1.57 | 0.431 | 0.89(0.67,1.09) |
性别 | 0.103 | 3.51 | 1.13 | 0.512 | 1.11(0.81,1.78) |
ECOG体质状态评分 | -0.391 | 4.43 | 4.78 | 0.018 | 0.68(0.31,0.89) |
病理学分期 | -0.073 | 2.78 | 1.01 | 0.663 | 0.93(0.57,1.32) |
吸烟史 | 0.111 | 2.12 | 1.09 | 0.518 | 1.12(0.83,1.41) |
组织学类型 | -0.156 | 3.31 | 1.89 | 0.311 | 0.86(0.61,1.16) |
PD-1抑制剂治疗线数 | -0.083 | 4.41 | 1.06 | 0.578 | 0.92(0.72,1.15) |
转移病灶数目 | -0.416 | 3.13 | 6.34 | 0.012 | 0.66(0.21,0.79) |
靶向药物治疗史 | -0.081 | 2.11 | 1.03 | 0.589 | 0.92(0.69,1.23) |
Table 1 Univariate Cox proportional hazards regression analysis of PFS in elderly patients with advanced NSCLC treated with PD-1 inhibitors
变量 | B | SE | Wald χ2值 | P值 | HR(95%CI) |
---|---|---|---|---|---|
年龄 | -0.112 | 2.45 | 1.57 | 0.431 | 0.89(0.67,1.09) |
性别 | 0.103 | 3.51 | 1.13 | 0.512 | 1.11(0.81,1.78) |
ECOG体质状态评分 | -0.391 | 4.43 | 4.78 | 0.018 | 0.68(0.31,0.89) |
病理学分期 | -0.073 | 2.78 | 1.01 | 0.663 | 0.93(0.57,1.32) |
吸烟史 | 0.111 | 2.12 | 1.09 | 0.518 | 1.12(0.83,1.41) |
组织学类型 | -0.156 | 3.31 | 1.89 | 0.311 | 0.86(0.61,1.16) |
PD-1抑制剂治疗线数 | -0.083 | 4.41 | 1.06 | 0.578 | 0.92(0.72,1.15) |
转移病灶数目 | -0.416 | 3.13 | 6.34 | 0.012 | 0.66(0.21,0.79) |
靶向药物治疗史 | -0.081 | 2.11 | 1.03 | 0.589 | 0.92(0.69,1.23) |
变量 | B | SE | Wald χ2值 | P值 | HR(95%CI) |
---|---|---|---|---|---|
ECOG体质状态评分 | -0.303 | 3.34 | 3.91 | 0.031 | 0.58(0.35,0.91) |
转移病灶数目 | -0.398 | 2.78 | 5.15 | 0.021 | 0.54(0.26,0.86) |
Table 2 Multivariate Cox proportional hazards regression analysis of PFS in elderly patients with advanced NSCLC treated with PD-1 inhibitors
变量 | B | SE | Wald χ2值 | P值 | HR(95%CI) |
---|---|---|---|---|---|
ECOG体质状态评分 | -0.303 | 3.34 | 3.91 | 0.031 | 0.58(0.35,0.91) |
转移病灶数目 | -0.398 | 2.78 | 5.15 | 0.021 | 0.54(0.26,0.86) |
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