Chinese General Practice ›› 2023, Vol. 26 ›› Issue (35): 4372-4381.DOI: 10.12114/j.issn.1007-9572.2023.0336

• Article • Previous Articles     Next Articles

Interpretation of the 2023 AGS Beers Criteria: Potentially Inappropriate Medication Use in Older Adults

  

  1. Department of Pharmacy, China-Japan Friendship Hospital, Beijing 100029, China
  • Received:2023-06-05 Revised:2023-06-15 Published:2023-12-15 Online:2023-06-29
  • Contact: LI Pengmei

美国老年医学会老年人潜在不适当用药Beers标准2023版解读

  

  1. 100029 北京市,中日友好医院药学部
  • 通讯作者: 李朋梅
  • 作者简介:
    作者贡献:张倩进行文章的构思与设计,文章的可行性分析,撰写论文,负责论文修订,对文章整体负责,监督管理;李沭进行了资料收集,表格编辑和整理;李朋梅负责文章的质量控制及审校,以及对文章整体负责。
  • 基金资助:
    国家重点研发计划主动健康和老龄化科技应对重点专项资助(2020YFC2005500,2020YFC2005504)

Abstract:

The Beers criteria is a tool for evaluating potentially inappropriate medication (PIM) in elderly patients widely used in various fields, such as clinical practice, teaching research, supervision and administration. The 2023 American Geriatrics Society Beers criteria (AGS Beers criteria) for PIM use in older adults are the seventh overall update, using the development methodology following previous versions, which includes the rigor of the evidence review and synthesis process. This paper provides a detailed interpretation of the new version of AGS Beers criteria. The AGS Beers criteria aims to reduce the incidence of PIM in older adults by optimizing drug selection. The 2023 AGS Beers criteria can also be used in the education of clinicians and patients, assessment of care quality, health care costs and drug use patterns in older adults. In addition to the five tables associated with PIM as main contents, several drugs and criteria have been added based on updated evidence, mainly on the revisions and streamlining of existing drugs and criteria. The added and revised content mainly involves anticoagulants, antiplatelet agents and hypoglycemic agents. The synthesis of anticoagulation recommendations has been added in the new version of AGS Beers criteria. Thirty-three drugs were removed due to low usage or not on the U.S. market. The 2023 AGS Beers criteria summarizes seven principles on the application of Beers criteria to ensure proper clinical use. Overall, the 2023 AGS Beers criteria have improved its accuracy and utility, which can better identify and reduce PIM prescriptions for the elderly patients and further guide the clinical development of rational drug use regimens.

Key words: Potentially inappropriate medication, Beers criteria, Aged, American Geriatrics Society, Rational drug use

摘要:

Beers标准是用于评价老年患者潜在不适当用药(PIM)的工具,目前已广泛应用于临床实践、教学研究及管理监管等多个领域。2023年美国老年医学会(AGS)Beers标准是该标准建立至今的第7次更新,制订方法仍沿用之前版本,包括严格的证据审查和综合分析,本文对新版标准进行了详细解读。AGS Beers标准旨在通过优化药物的选择,减少老年人PIM的发生,2023版更新标准还可用于教育临床医务人员和患者,以及评估老年人护理质量、医疗成本和药物使用模式。新版标准的主要内容仍是PIM相关的五大列表,基于新的循证证据,增加了一些药物和标准,但更多的是对现有药物和标准的修订及精简。新增和修订的内容主要涉及了抗凝药、抗血小板药和降糖药,并新增抗凝治疗建议专栏;删除了当前在美国使用率低和已经退市的药物,共计33种。新版标准首次总结了关于如何应用Beers标准的7条原则,以保障临床正确使用。2023 AGS Beers标准提升了准确性和实用性,将更好地识别和减少老年患者PIM处方,进一步指导临床制订合理用药方案。

关键词: 潜在不适当用药, Beers标准, 老年人, 美国老年医学会, 合理用药