中国全科医学 ›› 2018, Vol. 21 ›› Issue (27): 3319-3322.DOI: 10.3969/j.issn.1007-9572.2018.00.091

• 专题研究 • 上一篇    下一篇

2型糖尿病合并脑桥梗死的影像学特征及影响因素分析

王红霞*,刘欣,王丽娟,吕娜   

  1. 100190北京市中关村医院神经内科
    *通信作者:王红霞,主治医师;E-mail:y66828@163.com
  • 出版日期:2018-09-20 发布日期:2018-09-20

Imaging Characteristics and Factors Influencing Pontine Infarction in Patients with Type 2 Diabetes Mellitus

WANG Hong-xia*,LIU Xin,WANG Li-juan,LYU Na   

  1. Department of Neurology,Zhongguancun Hospital of Beijing,Beijing 100190,China
    *Corresponding author:WANG Hong-xia,Attending physician;E-mail:y66828@163.com
  • Published:2018-09-20 Online:2018-09-20

摘要: 目的 分析2型糖尿病合并脑桥梗死患者的影像学特征及影响因素。方法 选取2015年3月—2017年3月于北京市中关村医院神经内科住院的经颅脑磁共振成像(MRI)确诊的急性脑桥梗死患者86例,根据是否患有2型糖尿病分为糖尿病组(n=38)和非糖尿病组(n=48)。比较两组影像学特征,分析2型糖尿病合并脑桥梗死的影响因素。结果 糖尿病组脑桥前内侧梗死、梗死灶由脑桥深部延伸至脑桥腹侧表面、基底动脉狭窄发生率均高于非糖尿病组(P<0.05)。多因素Logistic回归分析显示,脑卒中史〔OR(95%CI)=7.139(2.069,24.641),P=0.002〕与基底动脉狭窄〔OR(95%CI)=5.730(1.017,32.289),P=0.048〕是2型糖尿病合并脑桥梗死的危险因素。结论 2型糖尿病合并脑桥梗死具有特征性影像学改变,脑桥前内侧梗死、梗死灶由脑桥深部延伸至脑桥腹侧表面、基底动脉狭窄发生率高;脑卒中史与基底动脉狭窄是2型糖尿病合并脑桥梗死的危险因素。

关键词: 糖尿病, 2型;脑桥;磁共振成像

Abstract: Abjective To analyze the imaging characteristics and factors influencing pontine infarction in patients with the complication of type 2 diabetes mellitus.Methods A total of 86 patients diagnosed with acute pontine infarction by head MRI at the Department of Neurology of Zhongguancun Hospital of Beijing between March 2015 and March 2017 were included in the study.The patients were divided into a diabetes group(n=38) and a non-diabetes group(n=48) depending on the presence of type 2 diabetes.The imaging characteristics in the two groups were compared,and the influencing factors were analyzed.Results The incidence of anterior-medial pontine infarction and of lesions extending from the deep pons to the ventral surface of the pons,as well as the incidence of basilar artery stenosis were all higher in the diabetes group than the non-diabetes group(P<0.05).Multivariate Logistic regression showed that stroke history〔OR(95%CI)=7.139(2.069,24.641),P=0.002〕and basilar artery stenosis〔OR(95%CI)=5.730(1.017,32.289),P=0.048〕 were the risk factors for pontine infarction in the patients with diabetes.Conclusion Pontine infarction in the patients with type 2 diabetes exhibited characteristic imaging changes.The incidence of anterior-medial pontine infarction and of lesions extending from the deep pons to the ventral surface of the pons and basilar artery stenosiswas higher in patients with type 2 diabetes.Stroke history and basilar artery stenosis were risk factors for pontine infarction in the patients with type 2 diabetes.

Key words: Diabetes mellitus, type 2;Pons;Magnetic resonance imaging