中国全科医学 ›› 2026, Vol. 29 ›› Issue (14): 1849-1857.DOI: 10.12114/j.issn.1007-9572.2025.0260

• 论著 • 上一篇    下一篇

基于肠神经系统调节作用探讨揿针改善慢性便秘与混合痔共病患者痔术后排便情况的前瞻性随机对照研究

姜楠1, 杨巍2,*()   

  1. 1.200237 上海市徐汇区大华医院消化科
    2.200000 上海市,上海中医药大学附属曙光医院肛肠科
  • 收稿日期:2025-06-08 修回日期:2025-12-21 出版日期:2026-05-15 发布日期:2026-04-14
  • 通讯作者: 杨巍

  • 作者贡献:

    姜楠负责课题设计、进行方案制定、临床病例筛选与统计分析,并撰写论文初稿,完成数据整理与图表绘制;杨巍指导研究设计与研究总体把控。

  • 基金资助:
    杨巍全国名老中医药专家传承工作室; 上海市卫生健康委员会临床重点专科建设项目(shslczdzk04302); 上海市科学技术委员会科技计划项目(20Y21901000); 上海市卫生健康委员会科研计划项目(20204Y0180); 上海市徐汇区科学技术委员会项目(SHXH202428)

A Prospective Randomized Controlled Trial on the Effects of Press Needle Therapy on Improving Bowel Movements in Patients with Chronic Constipation and Mixed Hemorrhoids Following Hemorrhoidectomy Based on Regulating Intestinal Nerve Function

JIANG Nan1, YANG Wei2,*()   

  1. 1. Department of Gastroenterology, Dahua Hospital, Xuhui District, Shanghai 200237, China
    2. Department of Anorectal Surgery, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200000, China
  • Received:2025-06-08 Revised:2025-12-21 Published:2026-05-15 Online:2026-04-14
  • Contact: YANG Wei

摘要: 背景 临床上合并便秘的混合痔患者术后常出现排便困难、创面愈合延迟及复发率升高。尽管已有研究证实揿针可改善单纯混合痔术后排便功能,但针对既往存在慢性便秘基础的混合痔患者痔术后排便干预研究较少。目的 通过随机对照临床试验,观察揿针对慢性便秘与Ⅲ、Ⅳ度混合痔共病患者术后排便管理的临床效果,提高患者生活质量。方法 选取2023年3月—2024年3月于上海中医药大学附属曙光医院肛肠科病房住院治疗的慢性便秘与Ⅲ、Ⅳ度混合痔共病且拟接受混合痔手术的患者96例,随机分为治疗组和对照组,各48例。治疗组接受揿针联合乳果糖治疗,对照组接受口服乳果糖治疗,疗程28 d。观察患者平均每周自发排便次数变化量和术后首次自发排便所需时间。分别于治疗前后评价患者中医证候积分、焦虑自评量表评分、抑郁自评量表评分。于术后第1、3、5、7、14、28天评价患者术后创面疼痛评分。于术后第1、3、5、7、14天评价患者术后创面水肿评分。使用便秘患者症状自评量表(PAC-SYM)分别记录两组患者治疗前、术后第5天、术后第7天、术后第14天、术后第28天评分。于治疗前后对临床疗效进行评价。结果 治疗组平均每周自发排便次数变化量优于对照组(P<0.05)。治疗组术后首次自发排便所需时间短于对照组(P<0.05)。治疗组治疗后中医证候积分低于对照组(P<0.05)。治疗组治疗后抑郁自评量表评分低于对照组(P<0.05)。广义估计方程(GEE)组间主效应结果显示,组别与时间对术后疼痛评分、水肿评分、PAC-SYM评分主效应均显著(P<0.001);组别与时间对术后疼痛评分、水肿评分、PAC-SYM评分均存在交互作用(P<0.001)。治疗组术后第3、5、7、14天视觉模拟疼痛评分均低于对照组(P<0.05)。术后第7天,治疗组创面水肿评分低于对照组(P<0.05)。术后第5、7、14、28天,治疗组PAC-SYM评分均低于对照组(P<0.05)。治疗组总有效率为87.5%(42/48),高于对照组的56.2%(27/48)(P<0.05)。结论 揿针能改善慢性便秘与混合痔共病患者的术后排便功能,促进创面恢复且有效缓解创面水肿、疼痛等不良反应,其作用或与肠脑轴功能的调节及肠动力的改善有关,该方法具有安全、简便、依从性好的特点,可作为便秘-痔共病患者围术期综合管理的可行方案。

关键词: 混合痔, 便秘, 揿针, 术后排便, 随机对照试验

Abstract:

Background

In clinical practice, patients with mixed hemorrhoids complicated by chronic constipation often experience postoperative difficulties in bowel movements, delayed wound healing, and increased recurrence rates. Although previous studies have confirmed that press needle therapy can improve postoperative bowel function in patients with uncomplicated mixed hemorrhoids, there is limited research on postoperative bowel management in patients with mixed hemorrhoids and a background of chronic constipation.

Objective

To observe the clinical effects of press needle therapy on postoperative bowel management in patients with chronic constipation and gradeⅢ-Ⅳ mixed hemorrhoids through a prospective randomized controlled trial, with the goal of improving patients' quality of life.

Methods

From March 2023 to March 2024, 96 patients with chronic constipation and gradeⅢ-Ⅳ mixed hemorrhoids, who were scheduled for hemorrhoidectomy, were enrolled at the Department of Anorectal Surgery, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine. The patients were randomly divided into a treatment group and a control group, each comprising 48 patients. The treatment group received press needle therapy combined with oral lactulose, while the control group received oral lactulose alone for 28 days. The study measured changes in the average weekly number of spontaneous bowel movements and the time to the first postoperative spontaneous bowel movement. Traditional Chinese Medicine syndrome scores, Self-rating Anxiety Scale (SAS) scores, and Self-rating Depression Scale (SDS) scores were assessed before and after treatment. Postoperative wound pain was evaluated on days 1, 3, 5, 7, 14, and 28, and wound oedema was assessed on days 1, 3, 5, 7, and 14. The Patient Assessment of Constipation Symptoms (PAC-SYM) questionnaire was administered before treatment and on postoperative days 5, 7, 14, and 28. Clinical efficacy was evaluated before and after treatment.

Results

The treatment group showed a greater increase in the average weekly number of spontaneous bowel movements compared to the control group (P<0.05). The time of the first postoperative spontaneous bowel movement was significantly shorter in the treatment group (P<0.05). After treatment, TCM syndrome scores and depression scores were significantly lower in the treatment group than in the control group (P<0.05). Generalized estimating equation (GEE) analysis showed significant main effects of group and time on postoperative pain scores, oedema scores, and PAC-SYM scores (P<0.001), as well as significant group-time interaction effects (P<0.001). On postoperative days 3, 5, 7, and 14, VAS scores were significantly lower in the treatment group than in the control group (P<0.05). On postoperative day 7, wound oedema scores were significantly lower in the treatment group (P<0.05). PAC-SYM scores on postoperative days 5, 7, 14, and 28 were significantly lower in the treatment group (P<0.05). The overall response rate in the treatment group was 87.5% (42/48), significantly higher than the control group's 56.2% (27/48)(P<0.05).

Conclusion

Press needle therapy can improve postoperative bowel function in patients with chronic constipation and mixed hemorrhoids, promote wound recovery, and alleviate adverse postoperative reactions such as pain and oedema. Its effects may be related to the regulation of the gut-brain axis and the improvement of intestinal motility. This method is safe, simple, and well-accepted by patients, making it a viable option for perioperative comprehensive management of patients with constipation-hemorrhoid comorbidity.

Key words: Mixed hemorrhoids, Constipation, Press needle therapy, Postoperative defecation, Randomized controlled trial