关键词: 肺疾病, 慢性阻塞性；稳定期；疾病管理；移动医疗

Abstract: Background　Chronic obstructive pulmonary disease（COPD） requires long-term and effective health management. Mobile APP has many merits in facilitating chronic disease management as an emerging method，but its effect in comprehensive management of stable COPD patients has been insufficiently studied. Objective　To examine the effect of mobile terminal-based comprehensive management in stable COPD patients. Methods　Eighty stable COPD patients treated in Fangzhuang Community Health Service Center of Fengtai District，Beijing from January to December 2019 were randomly divided into control group and observation group. The control group received routine outpatient treatment and health education，and the observational group received routine outpatient treatment and health education with mobile terminal-based management. Comparisons were made between two groups in terms of the grasp of COPD knowledge and breathing skills，mental state，treatment adherence，lung function indices，clinical assessment of symptoms，and status of acute exacerbation at baseline and 12 months after intervention. Results　After the intervention，the proportion of patients with increased knowledge of the etiology，main symptoms and preventive measures of COPD in the observation group was higher than those in the control group（P<0.05）. The patients in the observation group had better mastery of lip contraction breathing and abdominal breathing than those in the control group after the intervention（P<0.05）. After the intervention，the scores of depression and anxiety，the treatment compliance scores of correct medication，diet control and respiratory function exercise and the scores of CAT and mMRC in the observation group were lower than those before the intervention and lower than those in the control group after the intervention（P<0.05）. There was no significant difference in FEV1% and FEV1/FVC between the control group after intervention and before intervention（P>0.05）. After the intervention，FEV1% and FEV1/FVC in the observation group were higher than those before the intervention，and higher than those in the control group after the intervention（P<0.05）. There was no significant difference in the number of emergency and hospitalization in the control group after intervention（P>0.05）. After the intervention, the times of emergency and hospitalization in the observation group were less than those before the intervention，and the times of emergency were less than those in the control group after the intervention（P<0.05）. Conclusion　Mobile terminal-based management may contribute to the grasp of COPD knowledge and breathing skills，alleviation of negative mood，improvement of treatment adherence，lung function indicators，and clinical symptoms，as well as the reduction of possibility of acute exacerbation in stable COPD patients.

Key words: Pulmonary disease, chronic obstructive；Stable phase；Disease management；Mobile health