中国全科医学 ›› 2020, Vol. 23 ›› Issue (2): 198-203.DOI: 10.12114/j.issn.1007-9572.2019.00.651

• 专题研究 • 上一篇    下一篇

幽门螺杆菌阴性胃癌的研究现状与思考

王炯1,2,郭庆红1,2,姬瑞1,2,陈兆峰1,2,王玉平1,2,关泉林3,周永宁1,2*   

  1. 1.730000甘肃省兰州市,兰州大学第一医院消化科 2.730000甘肃省兰州市,兰州大学甘肃省胃肠病重点实验室 3.730000甘肃省兰州市,兰州大学第一医院肿瘤外科
    *通信作者:周永宁,教授,主任医师,博士研究生导师;E-mail:yongningzhou@sina.com
  • 出版日期:2020-01-15 发布日期:2020-01-15
  • 基金资助:
    国家自然科学基金资助项目(81570783);国家重点研发计划(2017YFC0908302,2016YFC1302201);甘肃省重点研发计划(18YF1FA110);甘肃省自然科学基金资助项目(18JR3RA366);兰州大学第一医院院内基金(ldyyyn2018-54)

Current Status and Thinking of Helicobacter Pylori-negative Gastric Cancer 

WANG Jiong1,2,GUO Qinghong1,2,JI Rui1,2,CHEN Zhaofeng1,2,WANG Yuping1,2,GUAN Quanlin3,ZHOU Yongning1,2*   

  1. 1.Department of Gastroenterology,the First Hospital of Lanzhou University,Lanzhou 730000,China
    2.Gansu Key Laboratory of Gastroenterology,Lanzhou University,Lanzhou 730000,China
    3.Department of Oncological Surgery,the First Hospital of Lanzhou University,Lanzhou 730000,China
    *Corresponding author:ZHOU Yongning,Professor,Chief physician,Doctoral supervisor;E-mail:yongningzhou@sina.com
  • Published:2020-01-15 Online:2020-01-15

摘要: 幽门螺杆菌阴性胃癌(HpNGC)是一种不同于幽门螺杆菌阳性胃癌(HpPGC)的疾病实体,在定义、诊断、临床病理特征、预后上具有独特性。HpNGC发病率低、临床病例资料少,国内尚缺乏相关研究。因此,本文做一综述,阐明其研究现状,以期增加对HpNGC的认识与关注,同时也为后继研究提供一定的参考。

关键词: 胃肿瘤, 幽门螺杆菌, 幽门螺杆菌阴性胃癌, 幽门螺杆菌阳性胃癌, 诊断, 预后

Abstract: Helicobacter pylori-negative gastric cancer (HpNGC) is a disease entity that is different from Helicobacter pylori-positive gastric cancer (HpPGC),with its uniqueness in definition,diagnosis,clinicopathological features,and prognosis.The incidence of HpNGC is low,and its clinical case data is small.There is still no relevant research in China.Therefore,it is necessary to review researches on HpNGC and clarify its research status,in order to improve its understanding,draw more attention,and provide some reference for subsequent research.

Key words: Stomach neoplasms, Helicobacter pylori, Helicobacter pylori-negative gastric cancer, Helicobacter pylori-positive gastric cancer, Diagnosis, Prognosis