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http://www.chinagp.net E-mail:zgqkyx@chinagp.net.cn ·2939·
·典型病例研究·
儿童隐源性肝脓肿导致脓毒症合并非显性弥散性
血管内凝血一例报道并文献复习
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1
付强 1,2* ,王婷 ,晏霞 1 查看原文
【摘要】 儿童肝脓肿发病率低,查阅文献鲜有相关流行病学数据。肝脓肿可由胆管疾病、脓皮病、阑尾炎及创
伤等导致,而隐源性肝脓肿病因不明,可仅表现为持续发热,无明显腹部不适,对早期诊断带来一定困难,延迟诊断
可能发生脓毒症休克及弥散性血管内凝血(DIC),导致预后不良。本文报道 1 例耐甲氧西林金黄色葡萄球菌(MRSA)
感染引起的隐源性肝脓肿导致脓毒症合并非显性 DIC 诊治过程。儿童隐源性肝脓肿是一种罕见的导致脓毒症的病因,
不能确定感染灶时,除考虑血源性感染外,即使没有腹痛,也要将肝脓肿纳入鉴别诊断。
【关键词】 肝脓肿;隐源性肝脓肿;脓毒症;弥散性血管内凝血;耐甲氧西林金黄色葡萄糖球菌;儿童
【中图分类号】 R 515.4 【文献标识码】 D DOI:10.12114/j.issn.1007-9572.2022.0302
付强,王婷,晏霞 . 儿童隐源性肝脓肿导致脓毒症合并非显性弥散性血管内凝血一例报道并文献复习[J]. 中国
全科医学,2022,25(23):2939-2941,2946. [www.chinagp.net]
FU Q,WANG T,YAN X. Non-overt DIC in cryptogenic liver abscess-associated sepsis in children:a case report and
literature review[J]. Chinese General Practice,2022,25(23):2939-2941,2946.
Non-overt DIC in Cryptogenic Liver Abscess-associated Sepsis in Children:a Case Report and Literature Review
1
FU Qiang 1,2* ,WANG Ting ,YAN Xia 1
1.Department of Pediatrics,Jingzhou Hospital Affiliated to Yangtze University,Jingzhou 434020,China
2.Institute of Pediatrics,Yangtze University,Jingzhou 434020,China
*
Corresponding author:FU Qiang,Associate chief physician,Master supervisor;E-mail:641381043@qq.com
【Abstract】 Liver abscess is rare in children,which is caused by biliary tract disease,pyoderma,appendicitis or
trauma. There is little available relevant epidemiological data. In particular,cryptogenic liver abscess is difficult to diagnose at the
early stage due to unknown etiology,and few clinical manifestations such as persistent fever without obvious abdominal discomfort.
A delayed diagnosis may be associated with septic shock and DIC,leading to poor prognosis. We reported the diagnosis and
treatment of a child with non-overt DIC in sepsis associated with cryptogenic liver abscess induced by infection with methicillin-
resistant Staphylococcus aureus. The case report and literature review indicate that cryptogenic liver abscess is a rare cause of
sepsis in children,which should be considered as a potential causative factor of sepsis besides hematogenous infection when the
site of infection could not be determined regardless of whether abdominal pain is present or not.
【Key words】 Liver abscess;Cryptogenic liver abscess;Sepsis;Disseminated intravascular coagulation;
Methicillin-resistant Staphylococcus aureus;Child
儿童肝脓肿发病率低,查阅文献鲜有相关流行病学数据。 肿的治疗包括手术与穿刺置管引流术,并配合抗感染及支持
肝脓肿可由胆管疾病、脓皮病、阑尾炎及创伤等导致,而隐 治疗 [2] 。本文报道 1 例耐甲氧西林金黄色葡萄球菌(MRSA)
源性肝脓肿病因不明,可仅表现为持续发热,无明显腹部不适, 感染引起的隐源性肝脓肿导致脓毒症合并非显性 DIC 的诊治
给早期诊断带来一定困难,延迟诊断可能发生脓毒症休克及 过程,以期为临床提供借鉴。
弥散性血管内凝血(DIC),导致预后不良 [1] 。目前,肝脓 1 病例简介
患儿,女,10 岁,因“发热 1 周,加重伴精神不佳、面
基金项目:湖北省卫生计生委科研项目(WJ2018H210);湖 色苍白 3 d”于 2020-07-21 入住长江大学附属荆州医院儿科。
北省儿科联盟科学基金项目(HBPASF-2019-06) 患儿 1 周前无明显诱因出现发热,热峰 39.5 ℃,间隔 6 h 左
1.434020 湖北省荆州市,长江大学附属荆州医院儿科 右发热 1 次,无咳嗽,无尿频及尿急,无腹痛及腹泻,在家
2.434020 湖北省荆州市,长江大学儿科研究所
* 口服“感冒药”及“退热药”治疗 2 d,仍反复发热,5 d 前
通信作者:付强,副主任医师,硕士生导师;
E-mail:641381043@qq.com 在镇卫生院采用头孢哌酮舒巴坦钠静脉滴注治疗 3 d,无好转,
本文数字出版日期:2022-06-02 且症状加重,精神及食欲不佳,面色苍白,遂转至本院。患