Abstract: Background　Epidemiological studies have shown that the incidence of depression in college students is higher than that in the general population.The incidence of depression in Chinese college students is 13.25%-79.90%，while that of Chinese general population is only 5%-6%.Severe depression not only affects the learning efficiency and interpersonal communication of college students，but even suicidal thoughts or behaviors may occur in serious cases.Objective　To explore the influencing factors of depression among Chinese college students，providing theoretical support and guidance for the prevention and control of depression in this group.Methods　We searched the databases of PubMed，The Cochrane Library，CNKI，CBM，WanFang Data and VIP for articles about the influencing factors of depression among Chinese college students published from 1998 to 2018 using related subject words with keywords.RevMan 5.3 over R was used to perform the meta-analysis.Both fixed effects model and random effects model were used for sensitivity analysis of the calculated results.Results　19 studies with 7 related factors were included.Analysis found that living arrangement 〔OR=0.58，95%CI（0.43，0.78）〕and family economic status〔OR=0.42，95%CI（0.24，0.73）〕were influencing factors of depression in Chinese college students（P<0.05），but gender 〔OR=1.07，95%CI（0.91，1.25）〕，household registration type 〔OR=1.06，95%CI（0.93，1.21）〕，only child or not 〔OR=1.00，95%CI（0.83，1.21）〕，love status 〔OR=0.99，95%CI（0.73，1.34）〕，grade〔OR=0.94，95%CI（0.82，1.07）〕 were not （P>0.05）.Conclusion　In Chinese college students，living with parents，and good family economic status are associated with decreased risk of depression，while gender，rural household，only child，and love status have not been found to be associated with depression.

Key words: Depression, College students, Risk factors, Meta-analysis, Root cause analysis

摘要： 背景　流行病学研究表明，大学生抑郁发生率高于一般人群，我国大学生抑郁发生率为13.25%~79.90%，而一般人群仅为5%~6%。重度抑郁不仅会影响大学生的学习效率、人际交往，严重者甚至会出现自杀意念或行为。目的　探讨中国大学生抑郁的影响因素，为大学生抑郁的预防控制提供理论支持和指导意见。方法　采用主题词和关键词相结合的方法，计算机检索PubMed、The Cochrane Library、中国知网、中国生物医学文献数据库（CBM）、万方数据知识服务平台、维普网（VIP）等数据库，搜集关于中国大学生抑郁影响因素分析的相关研究，检索时限为1998—2018年。采用Review Manager 5.3和R软件对纳入文献进行Meta分析，对计算结果采用固定效应模型和随机效应模型做敏感性分析。结果　本研究共纳入19篇文献，7个相关因素进行Meta分析，结果显示，性别〔OR=1.07，95%CI（0.91，1.25）〕、户籍类型〔OR=1.06，95%CI（0.93，1.21）〕、是否独生子女〔OR=1.00，95%CI（0.83，1.21）〕、恋爱状态〔OR=0.99，95%CI（0.73，1.34）〕、年级〔OR=0.94，95%CI（0.82，1.07）〕与大学生抑郁的发生不存在关联（P>0.05）；家庭形式〔OR=0.58，95%CI（0.43，0.78）〕、家庭经济状况〔OR=0.42，95%CI（0.24，0.73）〕是大学生抑郁的影响因素（P<0.05）。结论　与双亲生活、家庭经济状况较好是大学生抑郁的保护因素，尚不能认为性别、户籍农村、是否独生子女、恋爱状态和与大学生抑郁的发生存在关联。

关键词: 抑郁, 大学生, 危险因素, Meta分析, 影响因素分析