Chinese General Practice ›› 2025, Vol. 28 ›› Issue (26): 3314-3320.DOI: 10.12114/j.issn.1007-9572.2024.0595
• Original Research·Epidemiological Study • Previous Articles Next Articles
Received:
2024-10-13
Revised:
2025-02-09
Published:
2025-09-15
Online:
2025-07-22
Contact:
ZHANG Li
通讯作者:
张丽
作者简介:
作者贡献:
尚忠华负责研究设计与构思,数据处理、统计分析及结果可视化分析,撰写论文初稿;蒋芝月、刘海燕负责研究统计学方法的设计、实施与结果解读;杨星、黄朝晖参与研究设计讨论,提供领域专业知识指导;张丽负责论文的全面修订、审阅与最终定稿,监督研究质量与过程控制,并提供资金支持。
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项目 | 1990年 | 2021年 | 1990—2021年EAPC(95%CI) | ||
---|---|---|---|---|---|
发病数(95%UI)(万例) | 标化发病率(95%UI)(1/10万) | 发病数(95%UI)(万例) | 标化发病率(95%UI)(1/10万) | ||
总计 | 5.784(4.632~7.140) | 11.80(9.48~14.54) | 13.279(9.596~17.260) | 13.37(9.61~17.50) | 0.88(0.70~1.07) |
年龄 | |||||
15~19岁 | 0.037(0.029~0.047) | 0.60(0.48~0.76) | 0.020(0.015~0.027) | 0.59(0.45~0.77) | -0.07(-0.15~0.01) |
20~24岁 | 0.100(0.073~0.131) | 1.54(1.13~2.03) | 0.064(0.046~0.088) | 1.87(1.33~2.57) | 0.80(0.65~0.94) |
25~29岁 | 0.224(0.171~0.289) | 4.18(3.21~5.40) | 0.218(0.155~0.289) | 5.33(3.79~7.08) | 1.24(0.98~1.50) |
30~34岁 | 0.425(0.322~0.548) | 10.08(7.63~12.99) | 0.744(0.529~0.982) | 12.73(9.05~16.79) | 1.23(1.03~1.44) |
35~39岁 | 0.725(0.556~0.916) | 16.44(12.61~20.76) | 1.050(0.741~1.410) | 20.36(14.37~27.33) | 1.07(0.88~1.26) |
40~44岁 | 0.729(0.565~0.924) | 22.85(17.71~28.97) | 1.266(0.903~1.659) | 28.37(20.24~37.20) | 1.22(0.97~1.46) |
45~49岁 | 0.584(0.461~0.739) | 23.96(18.89~30.29) | 1.617(1.138~2.174) | 29.80(20.98~40.06) | 1.49(1.20~1.78) |
50~54岁 | 0.683(0.533~0.866) | 30.40(23.73~38.57) | 2.061(1.408~2.725) | 34.51(23.57~45.62) | 0.90(0.65~1.15) |
55~59岁 | 0.686(0.542~0.861) | 33.23(26.25~41.70) | 1.947(1.382~2.522) | 35.36(25.10~45.80) | 0.64(0.42~0.87) |
60~64岁 | 0.512(0.407~0.628) | 29.90(23.74~36.63) | 1.195(0.879~1.574) | 32.84(24.15~43.26) | 0.89(0.66~1.12) |
65~69岁 | 0.425(0.347~0.512) | 30.67(25.01~36.89) | 1.263(0.924~1.634) | 32.42(23.72~41.95) | 0.57(0.36~0.79) |
70~74岁 | 0.323(0.265~0.398) | 31.99(26.23~39.46) | 0.848(0.641~1.086) | 30.90(23.37~39.57) | 0.23(0.03~0.43) |
75~79岁 | 0.204(0.166~0.247) | 31.39(25.67~38.12) | 0.503(0.366~0.638) | 28.72(20.9~36.42) | 0.02(-0.15~0.19) |
80~84岁 | 0.090(0.074~0.107) | 27.68(22.67~32.84) | 0.286(0.214~0.359) | 25.73(19.24~32.25) | 0.04(-0.14~0.23) |
≥85岁 | 0.037(0.030~0.045) | 26.68(21.59~32.48) | 0.197(0.142~0.249) | 22.65(16.38~28.66) | -0.47(-0.75~-0.19) |
Table 1 Incidence and trend changes of cervical cancer in China from 1990 to 2021
项目 | 1990年 | 2021年 | 1990—2021年EAPC(95%CI) | ||
---|---|---|---|---|---|
发病数(95%UI)(万例) | 标化发病率(95%UI)(1/10万) | 发病数(95%UI)(万例) | 标化发病率(95%UI)(1/10万) | ||
总计 | 5.784(4.632~7.140) | 11.80(9.48~14.54) | 13.279(9.596~17.260) | 13.37(9.61~17.50) | 0.88(0.70~1.07) |
年龄 | |||||
15~19岁 | 0.037(0.029~0.047) | 0.60(0.48~0.76) | 0.020(0.015~0.027) | 0.59(0.45~0.77) | -0.07(-0.15~0.01) |
20~24岁 | 0.100(0.073~0.131) | 1.54(1.13~2.03) | 0.064(0.046~0.088) | 1.87(1.33~2.57) | 0.80(0.65~0.94) |
25~29岁 | 0.224(0.171~0.289) | 4.18(3.21~5.40) | 0.218(0.155~0.289) | 5.33(3.79~7.08) | 1.24(0.98~1.50) |
30~34岁 | 0.425(0.322~0.548) | 10.08(7.63~12.99) | 0.744(0.529~0.982) | 12.73(9.05~16.79) | 1.23(1.03~1.44) |
35~39岁 | 0.725(0.556~0.916) | 16.44(12.61~20.76) | 1.050(0.741~1.410) | 20.36(14.37~27.33) | 1.07(0.88~1.26) |
40~44岁 | 0.729(0.565~0.924) | 22.85(17.71~28.97) | 1.266(0.903~1.659) | 28.37(20.24~37.20) | 1.22(0.97~1.46) |
45~49岁 | 0.584(0.461~0.739) | 23.96(18.89~30.29) | 1.617(1.138~2.174) | 29.80(20.98~40.06) | 1.49(1.20~1.78) |
50~54岁 | 0.683(0.533~0.866) | 30.40(23.73~38.57) | 2.061(1.408~2.725) | 34.51(23.57~45.62) | 0.90(0.65~1.15) |
55~59岁 | 0.686(0.542~0.861) | 33.23(26.25~41.70) | 1.947(1.382~2.522) | 35.36(25.10~45.80) | 0.64(0.42~0.87) |
60~64岁 | 0.512(0.407~0.628) | 29.90(23.74~36.63) | 1.195(0.879~1.574) | 32.84(24.15~43.26) | 0.89(0.66~1.12) |
65~69岁 | 0.425(0.347~0.512) | 30.67(25.01~36.89) | 1.263(0.924~1.634) | 32.42(23.72~41.95) | 0.57(0.36~0.79) |
70~74岁 | 0.323(0.265~0.398) | 31.99(26.23~39.46) | 0.848(0.641~1.086) | 30.90(23.37~39.57) | 0.23(0.03~0.43) |
75~79岁 | 0.204(0.166~0.247) | 31.39(25.67~38.12) | 0.503(0.366~0.638) | 28.72(20.9~36.42) | 0.02(-0.15~0.19) |
80~84岁 | 0.090(0.074~0.107) | 27.68(22.67~32.84) | 0.286(0.214~0.359) | 25.73(19.24~32.25) | 0.04(-0.14~0.23) |
≥85岁 | 0.037(0.030~0.045) | 26.68(21.59~32.48) | 0.197(0.142~0.249) | 22.65(16.38~28.66) | -0.47(-0.75~-0.19) |
项目 | 1990年 | 2021年 | 1990—2021年EAPC(95%CI) | |||
---|---|---|---|---|---|---|
死亡数(95%UI)(万例) | 标化死亡率(95%UI)(1/10万) | 死亡数(95%UI)(万例) | 标化死亡率(95%UI)(1/10万) | |||
总计 | 3.180(2.583~3.908) | 6.98(5.70~8.56) | 4.984(3.688~6.439) | 4.64(3.44~6.00) | -1.05(-1.20~-0.89) | |
年龄 | ||||||
15~19岁 | 0.010(0.008~0.013) | 0.16(0.13~0.20) | 0.002(0.002~0.003) | 0.07(0.05~0.09) | -2.95(-3.09~-2.81) | |
20~24岁 | 0.027(0.020~0.036) | 0.42(0.31~0.56) | 0.008(0.006~0.011) | 0.22(0.16~0.31) | -2.16(-2.33~-1.99) | |
25~29岁 | 0.056(0.042~0.072) | 1.04(0.79~1.35) | 0.023(0.017~0.031) | 0.57(0.40~0.76) | -1.78(-1.98~-1.58) | |
30~34岁 | 0.111(0.085~0.143) | 2.64(2.01~3.38) | 0.086(0.060~0.114) | 1.47(1.03~1.94) | -1.68(-1.84~-1.52) | |
35~39岁 | 0.228(0.178~0.288) | 5.17(4.02~6.53) | 0.153(0.108~0.205) | 2.96(2.09~3.97) | -1.62(-1.79~-1.45) | |
40~44岁 | 0.288(0.223~0.365) | 9.01(6.98~11.42) | 0.242(0.174~0.319) | 5.43(3.90~7.15) | -1.33(-1.52~-1.13) | |
45~49岁 | 0.282(0.224~0.355) | 11.58(9.20~14.58) | 0.407(0.288~0.554) | 7.50(5.31~10.2) | -0.87(-1.08~-0.65) | |
50~54岁 | 0.391(0.305~0.497) | 17.43(13.57~22.12) | 0.672(0.469~0.896) | 11.25(7.85~15.01) | -1.13(-1.36~-0.91) | |
55~59岁 | 0.438(0.349~0.546) | 21.22(16.89~26.44) | 0.745(0.527~0.974) | 13.52(9.57~17.69) | -1.22(-1.41~-1.02) | |
60~64岁 | 0.357(0.284~0.436) | 20.82(16.59~25.44) | 0.518(0.385~0.683) | 14.24(10.59~18.76) | -0.84(-1.01~-0.67) | |
65~69岁 | 0.336(0.274~0.404) | 24.19(19.74~29.11) | 0.660(0.489~0.858) | 16.94(12.56~22.02) | -0.92(-1.10~-0.73) | |
70~74岁 | 0.294(0.243~0.364) | 29.15(24.06~36.06) | 0.559(0.423~0.714) | 20.39(15.42~26.04) | -0.93(-1.10~-0.76) | |
75~79岁 | 0.208(0.170~0.252) | 32.13(26.23~38.94) | 0.398(0.295~0.506) | 22.72(16.81~28.87) | -0.91(-1.06~-0.76) | |
80~84岁 | 0.105(0.086~0.124) | 32.11(26.27~38.17) | 0.278(0.209~0.348) | 25.00(18.81~31.26) | -0.61(-0.80~-0.41) | |
≥85岁 | 0.049(0.039~0.059) | 34.86(28.26~42.37) | 0.233(0.169~0.294) | 26.85(19.47~33.88) | -0.83(-1.13~-0.54) |
Table 2 Mortality and trend changes of cervical cancer in China from 1990 to 2021
项目 | 1990年 | 2021年 | 1990—2021年EAPC(95%CI) | |||
---|---|---|---|---|---|---|
死亡数(95%UI)(万例) | 标化死亡率(95%UI)(1/10万) | 死亡数(95%UI)(万例) | 标化死亡率(95%UI)(1/10万) | |||
总计 | 3.180(2.583~3.908) | 6.98(5.70~8.56) | 4.984(3.688~6.439) | 4.64(3.44~6.00) | -1.05(-1.20~-0.89) | |
年龄 | ||||||
15~19岁 | 0.010(0.008~0.013) | 0.16(0.13~0.20) | 0.002(0.002~0.003) | 0.07(0.05~0.09) | -2.95(-3.09~-2.81) | |
20~24岁 | 0.027(0.020~0.036) | 0.42(0.31~0.56) | 0.008(0.006~0.011) | 0.22(0.16~0.31) | -2.16(-2.33~-1.99) | |
25~29岁 | 0.056(0.042~0.072) | 1.04(0.79~1.35) | 0.023(0.017~0.031) | 0.57(0.40~0.76) | -1.78(-1.98~-1.58) | |
30~34岁 | 0.111(0.085~0.143) | 2.64(2.01~3.38) | 0.086(0.060~0.114) | 1.47(1.03~1.94) | -1.68(-1.84~-1.52) | |
35~39岁 | 0.228(0.178~0.288) | 5.17(4.02~6.53) | 0.153(0.108~0.205) | 2.96(2.09~3.97) | -1.62(-1.79~-1.45) | |
40~44岁 | 0.288(0.223~0.365) | 9.01(6.98~11.42) | 0.242(0.174~0.319) | 5.43(3.90~7.15) | -1.33(-1.52~-1.13) | |
45~49岁 | 0.282(0.224~0.355) | 11.58(9.20~14.58) | 0.407(0.288~0.554) | 7.50(5.31~10.2) | -0.87(-1.08~-0.65) | |
50~54岁 | 0.391(0.305~0.497) | 17.43(13.57~22.12) | 0.672(0.469~0.896) | 11.25(7.85~15.01) | -1.13(-1.36~-0.91) | |
55~59岁 | 0.438(0.349~0.546) | 21.22(16.89~26.44) | 0.745(0.527~0.974) | 13.52(9.57~17.69) | -1.22(-1.41~-1.02) | |
60~64岁 | 0.357(0.284~0.436) | 20.82(16.59~25.44) | 0.518(0.385~0.683) | 14.24(10.59~18.76) | -0.84(-1.01~-0.67) | |
65~69岁 | 0.336(0.274~0.404) | 24.19(19.74~29.11) | 0.660(0.489~0.858) | 16.94(12.56~22.02) | -0.92(-1.10~-0.73) | |
70~74岁 | 0.294(0.243~0.364) | 29.15(24.06~36.06) | 0.559(0.423~0.714) | 20.39(15.42~26.04) | -0.93(-1.10~-0.76) | |
75~79岁 | 0.208(0.170~0.252) | 32.13(26.23~38.94) | 0.398(0.295~0.506) | 22.72(16.81~28.87) | -0.91(-1.06~-0.76) | |
80~84岁 | 0.105(0.086~0.124) | 32.11(26.27~38.17) | 0.278(0.209~0.348) | 25.00(18.81~31.26) | -0.61(-0.80~-0.41) | |
≥85岁 | 0.049(0.039~0.059) | 34.86(28.26~42.37) | 0.233(0.169~0.294) | 26.85(19.47~33.88) | -0.83(-1.13~-0.54) |
项目 | 1990年 | 2021年 | 1990—2021年EAPC(95%CI) | ||
---|---|---|---|---|---|
DALYs(95%UI)(万人年) | 标化DALYs率(95%UI)(1/10万) | DALYs(95%UI)(万人年) | 标化DALYs率(95%UI)(1/10万) | ||
总计 | 111.620(89.426~138.105) | 228.22(183.51~282.00) | 154.779(111.982~200.923) | 149.84(108.94~195.58) | -1.07(-1.22~-0.92) |
年龄 | |||||
15~19岁 | 0.737(0.584~0.931) | 11.95(9.47~15.10) | 0.180(0.136~0.236) | 5.20(3.93~6.82) | -2.83(-2.97~-2.69) |
20~24岁 | 1.894(1.395~2.492) | 29.38(21.63~38.65) | 0.550(0.395~0.763) | 16.02(11.5~22.25) | -2.03(-2.20~-1.87) |
25~29岁 | 3.608(2.760~4.687) | 67.48(51.62~87.66) | 1.573(1.115~2.091) | 38.48(27.29~51.16) | -1.63(-1.83~-1.42) |
30~34岁 | 6.616(5.042~8.508) | 156.69(119.42~201.52) | 5.333(3.765~7.156) | 91.20(64.39~122.38) | -1.53(-1.68~-1.37) |
35~39岁 | 12.374(9.596~15.687) | 280.51(217.53~355.62) | 8.632(6.102~11.491) | 167.29(118.25~222.70) | -1.49(-1.66~-1.32) |
40~44岁 | 14.104(10.969~17.858) | 441.95(343.72~559.55) | 12.246(8.747~16.082) | 274.52(196.09~360.53) | -1.23(-1.43~-1.02) |
45~49岁 | 12.349(9.799~15.562) | 506.52(401.93~638.31) | 18.253(12.965~24.766) | 336.39(238.94~456.42) | -0.78(-0.99~-0.56) |
50~54岁 | 15.167(11.781~19.271) | 675.43(524.64~858.2) | 26.608(18.592~35.374) | 445.56(311.34~592.36) | -1.05(-1.28~-0.83) |
55~59岁 | 14.918(11.870~18.602) | 722.74(575.07~901.24) | 25.875(18.274~33.917) | 469.96(331.91~616.02) | -1.15(-1.35~-0.94) |
60~64岁 | 10.453(8.338~12.788) | 610.06(486.65~746.34) | 15.410(11.418~20.253) | 423.58(313.85~556.70) | -0.78(-0.95~-0.62) |
65~69岁 | 8.262(6.748~9.962) | 595.55(486.42~718.06) | 16.446(12.149~21.378) | 422.08(311.81~548.66) | -0.86(-1.05~-0.68) |
70~74岁 | 5.949(4.920~7.356) | 589.44(487.51~728.84) | 11.439(8.622~14.637) | 416.88(314.22~533.43) | -0.90(-1.07~-0.72) |
75~79岁 | 3.380(2.756~4.089) | 521.25(425.03~630.67) | 6.465(4.769~8.199) | 369.10(272.28~468.06) | -0.91(-1.06~-0.76) |
80~84岁 | 1.328(1.086~1.578) | 407.81(333.52~484.32) | 3.520(2.651~4.407) | 316.67(238.46~396.44) | -0.62(-0.81~-0.43) |
≥85岁 | 0.482(0.391~0.586) | 344.93(279.86~419.94) | 2.250(1.633~2.837) | 259.07(187.98~326.56) | -0.91(-1.20~-0.61) |
Table 3 DALYs and trend changes of cervical cancer in China from 1990 to 2021
项目 | 1990年 | 2021年 | 1990—2021年EAPC(95%CI) | ||
---|---|---|---|---|---|
DALYs(95%UI)(万人年) | 标化DALYs率(95%UI)(1/10万) | DALYs(95%UI)(万人年) | 标化DALYs率(95%UI)(1/10万) | ||
总计 | 111.620(89.426~138.105) | 228.22(183.51~282.00) | 154.779(111.982~200.923) | 149.84(108.94~195.58) | -1.07(-1.22~-0.92) |
年龄 | |||||
15~19岁 | 0.737(0.584~0.931) | 11.95(9.47~15.10) | 0.180(0.136~0.236) | 5.20(3.93~6.82) | -2.83(-2.97~-2.69) |
20~24岁 | 1.894(1.395~2.492) | 29.38(21.63~38.65) | 0.550(0.395~0.763) | 16.02(11.5~22.25) | -2.03(-2.20~-1.87) |
25~29岁 | 3.608(2.760~4.687) | 67.48(51.62~87.66) | 1.573(1.115~2.091) | 38.48(27.29~51.16) | -1.63(-1.83~-1.42) |
30~34岁 | 6.616(5.042~8.508) | 156.69(119.42~201.52) | 5.333(3.765~7.156) | 91.20(64.39~122.38) | -1.53(-1.68~-1.37) |
35~39岁 | 12.374(9.596~15.687) | 280.51(217.53~355.62) | 8.632(6.102~11.491) | 167.29(118.25~222.70) | -1.49(-1.66~-1.32) |
40~44岁 | 14.104(10.969~17.858) | 441.95(343.72~559.55) | 12.246(8.747~16.082) | 274.52(196.09~360.53) | -1.23(-1.43~-1.02) |
45~49岁 | 12.349(9.799~15.562) | 506.52(401.93~638.31) | 18.253(12.965~24.766) | 336.39(238.94~456.42) | -0.78(-0.99~-0.56) |
50~54岁 | 15.167(11.781~19.271) | 675.43(524.64~858.2) | 26.608(18.592~35.374) | 445.56(311.34~592.36) | -1.05(-1.28~-0.83) |
55~59岁 | 14.918(11.870~18.602) | 722.74(575.07~901.24) | 25.875(18.274~33.917) | 469.96(331.91~616.02) | -1.15(-1.35~-0.94) |
60~64岁 | 10.453(8.338~12.788) | 610.06(486.65~746.34) | 15.410(11.418~20.253) | 423.58(313.85~556.70) | -0.78(-0.95~-0.62) |
65~69岁 | 8.262(6.748~9.962) | 595.55(486.42~718.06) | 16.446(12.149~21.378) | 422.08(311.81~548.66) | -0.86(-1.05~-0.68) |
70~74岁 | 5.949(4.920~7.356) | 589.44(487.51~728.84) | 11.439(8.622~14.637) | 416.88(314.22~533.43) | -0.90(-1.07~-0.72) |
75~79岁 | 3.380(2.756~4.089) | 521.25(425.03~630.67) | 6.465(4.769~8.199) | 369.10(272.28~468.06) | -0.91(-1.06~-0.76) |
80~84岁 | 1.328(1.086~1.578) | 407.81(333.52~484.32) | 3.520(2.651~4.407) | 316.67(238.46~396.44) | -0.62(-0.81~-0.43) |
≥85岁 | 0.482(0.391~0.586) | 344.93(279.86~419.94) | 2.250(1.633~2.837) | 259.07(187.98~326.56) | -0.91(-1.20~-0.61) |
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