Chinese General Practice ›› 2023, Vol. 26 ›› Issue (21): 2626-2631.DOI: 10.12114/j.issn.1007-9572.2022.0778
Special Issue: 女性健康最新文章合集
• Original Research • Previous Articles Next Articles
Received:
2022-09-23
Revised:
2022-12-10
Published:
2023-07-20
Online:
2023-01-10
Contact:
RAN Limei
通讯作者:
冉利梅
作者简介:
基金资助:
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2022.0778
项目 | 例数 | 年龄(岁) | BMI(kg/m2) | 腰围(cm) | 脂肪量(kg) | VFA(cm2) | ALM(kg) | 躯干肌肉量(kg) | 全身肌肉量(kg) | 腰椎BMD(g/cm2) | 股骨颈BMD(g/cm2) | 全髋BMD(g/cm2) |
---|---|---|---|---|---|---|---|---|---|---|---|---|
绝经前女性 | 1 261 | 46.0±3.7 | 23.6±3.1 | 76.91±5.58 | 17.78±4.66 | 67.50±27.09 | 18.01±1.98 | 18.45±1.63 | 36.46±3.52 | 1.14±0.15 | 0.91±0.12 | 0.97±0.12 |
绝经后女性 | 1 094 | 54.1±3.3 | 24.0±3.0 | 77.79±5.43 | 18.59±4.59 | 80.26±29.75 | 17.52±1.94 | 18.04±1.93 | 33.43±6.41 | 1.00±0.15 | 0.82±0.11 | 0.89±0.12 |
t值 | -57.18 | -3.78 | -3.86 | -4.27 | -10.81 | 6.08 | 5.49 | 13.89 | 22.24 | 18.20 | 16.29 | |
P值 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
Table 1 Comparison of the distribution of body composition and BMD in different parts of premenopausal and postmenopausal women
项目 | 例数 | 年龄(岁) | BMI(kg/m2) | 腰围(cm) | 脂肪量(kg) | VFA(cm2) | ALM(kg) | 躯干肌肉量(kg) | 全身肌肉量(kg) | 腰椎BMD(g/cm2) | 股骨颈BMD(g/cm2) | 全髋BMD(g/cm2) |
---|---|---|---|---|---|---|---|---|---|---|---|---|
绝经前女性 | 1 261 | 46.0±3.7 | 23.6±3.1 | 76.91±5.58 | 17.78±4.66 | 67.50±27.09 | 18.01±1.98 | 18.45±1.63 | 36.46±3.52 | 1.14±0.15 | 0.91±0.12 | 0.97±0.12 |
绝经后女性 | 1 094 | 54.1±3.3 | 24.0±3.0 | 77.79±5.43 | 18.59±4.59 | 80.26±29.75 | 17.52±1.94 | 18.04±1.93 | 33.43±6.41 | 1.00±0.15 | 0.82±0.11 | 0.89±0.12 |
t值 | -57.18 | -3.78 | -3.86 | -4.27 | -10.81 | 6.08 | 5.49 | 13.89 | 22.24 | 18.20 | 16.29 | |
P值 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
指标 | 绝经前女性 | 绝经后女性 | 总体检女性 | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BMI | 脂肪量 | VFA | ALM | 躯干肌肉量 | 全身肌肉量 | BMI | 脂肪量 | VFA | ALM | 躯干肌肉量 | 全身肌肉量 | BMI | 脂肪量 | VFA | ALM | 躯干肌肉量 | 全身肌肉量 | |
腰椎BMD | ||||||||||||||||||
r值 | 0.168 | 0.171 | 0.047 | 0.321 | 0.308 | 0.326 | 0.241 | 0.264 | 0.149 | 0.335 | 0.267 | 0.113 | 0.15 | 0.157 | -0.006 | 0.347 | 0.305 | 0.292 |
P值 | <0.001 | <0.001 | 0.096 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.789 | <0.001 | <0.001 | <0.001 |
股骨颈BMD | ||||||||||||||||||
r值 | 0.314 | 0.321 | 0.208 | 0.378 | 0.361 | 0.384 | 0.265 | 0.284 | 0.173 | 0.337 | 0.306 | 0.062 | 0.245 | 0.253 | 0.097 | 0.378 | 0.348 | 0.263 |
P值 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
全髋BMD | ||||||||||||||||||
r值 | 0.351 | 0.332 | 0.243 | 0.353 | 0.317 | 0.345 | 0.349 | 0.339 | 0.249 | 0.333 | 0.285 | 0.095 | 0.306 | 0.288 | 0.158 | 0.363 | 0.318 | 0.258 |
P值 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
Table 2 Correlation analysis of fat and muscle tissue with BMD in perimenopausal women
指标 | 绝经前女性 | 绝经后女性 | 总体检女性 | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BMI | 脂肪量 | VFA | ALM | 躯干肌肉量 | 全身肌肉量 | BMI | 脂肪量 | VFA | ALM | 躯干肌肉量 | 全身肌肉量 | BMI | 脂肪量 | VFA | ALM | 躯干肌肉量 | 全身肌肉量 | |
腰椎BMD | ||||||||||||||||||
r值 | 0.168 | 0.171 | 0.047 | 0.321 | 0.308 | 0.326 | 0.241 | 0.264 | 0.149 | 0.335 | 0.267 | 0.113 | 0.15 | 0.157 | -0.006 | 0.347 | 0.305 | 0.292 |
P值 | <0.001 | <0.001 | 0.096 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.789 | <0.001 | <0.001 | <0.001 |
股骨颈BMD | ||||||||||||||||||
r值 | 0.314 | 0.321 | 0.208 | 0.378 | 0.361 | 0.384 | 0.265 | 0.284 | 0.173 | 0.337 | 0.306 | 0.062 | 0.245 | 0.253 | 0.097 | 0.378 | 0.348 | 0.263 |
P值 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
全髋BMD | ||||||||||||||||||
r值 | 0.351 | 0.332 | 0.243 | 0.353 | 0.317 | 0.345 | 0.349 | 0.339 | 0.249 | 0.333 | 0.285 | 0.095 | 0.306 | 0.288 | 0.158 | 0.363 | 0.318 | 0.258 |
P值 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
自变量 | 腰椎BMD | 股骨颈BMD | 全髋BMD | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
B | SE | β | t值 | P值 | B | SE | β | t值 | P值 | B | SE | β | t值 | P值 | |
总体检女性 | |||||||||||||||
脂肪量 | -0.000 01 | 0.003 | 0.000 32 | -0.004 | 0.997 | 0.001 89 | 0.002 | 0.069 98 | 0.802 | 0.423 | -0.003 51 | 0.002 | -0.129 90 | -1.480 | 0.139 |
VFA | -0.005 91 | <0.001 | -0.104 67 | -1.653 | 0.098 | -0.000 47 | <0.001 | -0.108 74 | -1.697 | 0.090 | -0.000 24 | <0.001 | -0.055 40 | -0.859 | 0.390 |
ALM | 0.020 23 | 0.003 | 0.243 80 | 6.363 | <0.001 | 0.012 57 | 0.002 | 0.19875 | 5.126 | <0.001 | 0.012 63 | 0.002 | 0.198 93 | 5.100 | <0.001 |
躯干肌肉量 | 0.002 82 | 0.003 | 0.030 77 | 0.944 | 0.345 | 0.006 91 | 0.002 | 0.098 90 | 3.000 | 0.003 | 0.003 31 | 0.002 | 0.047 21 | 1.424 | 0.155 |
全身肌肉量 | 0.000 76 | 0.001 | 0.024 55 | 1.041 | 0.298 | -0.001 22 | 0.001 | -0.051 47 | -2.157 | 0.031 | -0.000 59 | 0.001 | -0.024 75 | -1.031 | 0.303 |
绝经前女性 | |||||||||||||||
脂肪量 | -0.006 39 | 0.005 | -0.200 22 | -1.259 | 0.208 | -0.001 86 | 0.004 | -0.072 67 | -0.468 | 0.640 | -0.006 10 | 0.004 | -0.239 14 | -1.537 | 0.125 |
VFA | -0.000 65 | 0.001 | -0.118 42 | -1.110 | 0.267 | -0.000 05 | <0.001 | -0.011 04 | -0.106 | 0.916 | -0.000 02 | <0.001 | -0.003 77 | -0.362 | 0.971 |
ALM | 0.004 58 | 0.008 | 0.060 99 | 0.575 | 0.561 | 0.002 37 | 0.006 | 0.039 38 | 0.371 | 0.711 | 0.007 47 | 0.006 | 0.124 56 | 1.171 | 0.242 |
躯干肌肉量 | 0.006 60 | 0.010 | 0.072 57 | 0.632 | 0.528 | -0.002 50 | 0.008 | -0.034 14 | -0.304 | 0.761 | -0.002 25 | 0.008 | -0.030 91 | -0.275 | 0.783 |
全身肌肉量 | 0.009 50 | 0.007 | 0.225 37 | 1.336 | 0.182 | 0.010 32 | 0.006 | 0.304 50 | 1.847 | 0.065 | 0.005 27 | 0.006 | 0.156 24 | 0.947 | 0.344 |
绝经后女性 | |||||||||||||||
脂肪量 | 0.004 05 | 0.005 | 0.123 93 | 0.848 | 0.396 | 0.001 03 | 0.004 | 0.041 38 | 0.284 | 0.776 | -0.00 194 | 0.004 | -0.074 53 | 0.517 | 0.606 |
VFA | -0.000 52 | 0.001 | -0.102 69 | -0.880 | 0.379 | -0.000 11 | <0.001 | -0.027 47 | 0.236 | 0.813 | <0.000 21 | <0.001 | -0.052 49 | -0.456 | 0.649 |
ALM | 0.017 42 | 0.005 | 0.225 75 | 3.772 | <0.001 | 0.012 71 | 0.004 | 0.215 73 | 3.620 | <0.001 | 0.011 54 | 0.004 | 0.187 86 | 3.178 | 0.002 |
躯干肌肉量 | 0.002 95 | 0.003 | 0.038 03 | 0.860 | 0.390 | 0.008 89 | 0.003 | 0.149 93 | 3.404 | <0.001 | 0.004 64 | 0.003 | 0.075 19 | 1.721 | 0.085 |
全身肌肉量 | -0.000 43 | 0.001 | -0.018 52 | -0.588 | 0.557 | -0.002 24 | 0.001 | -0.125 33 | -3.995 | <0.001 | -0.001 40 | 0.001 | -0.075 05 | -2.412 | 0.016 |
Table 3 Multiple linear regression analysis of influencing factors of BMD at different sites in perimenopausal women
自变量 | 腰椎BMD | 股骨颈BMD | 全髋BMD | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
B | SE | β | t值 | P值 | B | SE | β | t值 | P值 | B | SE | β | t值 | P值 | |
总体检女性 | |||||||||||||||
脂肪量 | -0.000 01 | 0.003 | 0.000 32 | -0.004 | 0.997 | 0.001 89 | 0.002 | 0.069 98 | 0.802 | 0.423 | -0.003 51 | 0.002 | -0.129 90 | -1.480 | 0.139 |
VFA | -0.005 91 | <0.001 | -0.104 67 | -1.653 | 0.098 | -0.000 47 | <0.001 | -0.108 74 | -1.697 | 0.090 | -0.000 24 | <0.001 | -0.055 40 | -0.859 | 0.390 |
ALM | 0.020 23 | 0.003 | 0.243 80 | 6.363 | <0.001 | 0.012 57 | 0.002 | 0.19875 | 5.126 | <0.001 | 0.012 63 | 0.002 | 0.198 93 | 5.100 | <0.001 |
躯干肌肉量 | 0.002 82 | 0.003 | 0.030 77 | 0.944 | 0.345 | 0.006 91 | 0.002 | 0.098 90 | 3.000 | 0.003 | 0.003 31 | 0.002 | 0.047 21 | 1.424 | 0.155 |
全身肌肉量 | 0.000 76 | 0.001 | 0.024 55 | 1.041 | 0.298 | -0.001 22 | 0.001 | -0.051 47 | -2.157 | 0.031 | -0.000 59 | 0.001 | -0.024 75 | -1.031 | 0.303 |
绝经前女性 | |||||||||||||||
脂肪量 | -0.006 39 | 0.005 | -0.200 22 | -1.259 | 0.208 | -0.001 86 | 0.004 | -0.072 67 | -0.468 | 0.640 | -0.006 10 | 0.004 | -0.239 14 | -1.537 | 0.125 |
VFA | -0.000 65 | 0.001 | -0.118 42 | -1.110 | 0.267 | -0.000 05 | <0.001 | -0.011 04 | -0.106 | 0.916 | -0.000 02 | <0.001 | -0.003 77 | -0.362 | 0.971 |
ALM | 0.004 58 | 0.008 | 0.060 99 | 0.575 | 0.561 | 0.002 37 | 0.006 | 0.039 38 | 0.371 | 0.711 | 0.007 47 | 0.006 | 0.124 56 | 1.171 | 0.242 |
躯干肌肉量 | 0.006 60 | 0.010 | 0.072 57 | 0.632 | 0.528 | -0.002 50 | 0.008 | -0.034 14 | -0.304 | 0.761 | -0.002 25 | 0.008 | -0.030 91 | -0.275 | 0.783 |
全身肌肉量 | 0.009 50 | 0.007 | 0.225 37 | 1.336 | 0.182 | 0.010 32 | 0.006 | 0.304 50 | 1.847 | 0.065 | 0.005 27 | 0.006 | 0.156 24 | 0.947 | 0.344 |
绝经后女性 | |||||||||||||||
脂肪量 | 0.004 05 | 0.005 | 0.123 93 | 0.848 | 0.396 | 0.001 03 | 0.004 | 0.041 38 | 0.284 | 0.776 | -0.00 194 | 0.004 | -0.074 53 | 0.517 | 0.606 |
VFA | -0.000 52 | 0.001 | -0.102 69 | -0.880 | 0.379 | -0.000 11 | <0.001 | -0.027 47 | 0.236 | 0.813 | <0.000 21 | <0.001 | -0.052 49 | -0.456 | 0.649 |
ALM | 0.017 42 | 0.005 | 0.225 75 | 3.772 | <0.001 | 0.012 71 | 0.004 | 0.215 73 | 3.620 | <0.001 | 0.011 54 | 0.004 | 0.187 86 | 3.178 | 0.002 |
躯干肌肉量 | 0.002 95 | 0.003 | 0.038 03 | 0.860 | 0.390 | 0.008 89 | 0.003 | 0.149 93 | 3.404 | <0.001 | 0.004 64 | 0.003 | 0.075 19 | 1.721 | 0.085 |
全身肌肉量 | -0.000 43 | 0.001 | -0.018 52 | -0.588 | 0.557 | -0.002 24 | 0.001 | -0.125 33 | -3.995 | <0.001 | -0.001 40 | 0.001 | -0.075 05 | -2.412 | 0.016 |
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