中国全科医学 ›› 2024, Vol. 27 ›› Issue (03): 273-279.DOI: 10.12114/j.issn.1007-9572.2023.0250

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冠状动脉微循环障碍与代谢综合征的研究进展

朱春临1, 高洁2,*()   

  1. 1100029 北京市,北京中医药大学研究生院
    2100191 北京市,中国中医科学院西苑医院科研处
  • 收稿日期:2023-03-23 修回日期:2023-06-20 出版日期:2024-01-20 发布日期:2023-10-23
  • 通讯作者: 高洁

  • 作者贡献:朱春临提出主要研究目标,负责检索文献、撰写论文;高洁负责文章的质量控制与审查,对文章整体负责,监督管理。
  • 基金资助:
    国家自然科学基金青年科学基金项目(81904046); 中央级公益性科研院所基本科研业务费专项资金资助(ZZ15-YQ-003); 国家中医心血管病临床医学研究中心专项科研基金(CMC2022004)

Advances in Coronary Microvascular Dysfunction and Metabolic Syndrome

ZHU Chunlin1, GAO Jie2,*()   

  1. 1Department of Graduate School, Beijing University of Chinese Medicine, Beijing 100029, China
    2Department of Scientific Research, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100191, China
  • Received:2023-03-23 Revised:2023-06-20 Published:2024-01-20 Online:2023-10-23
  • Contact: GAO Jie

摘要: 近年来,冠状动脉微循环障碍(CMD)和代谢综合征(MetS)因对心血管造成不利影响而备受关注。CMD是导致心肌缺血的一种潜在因素,与心血管疾病的发生、进展和不良预后密切相关。MetS是一组由遗传和环境因素共同作用而引起的代谢性疾病。CMD和MetS之间存在一定的关联,了解两种疾病之间复杂的相互作用对于制订有效的预防和治疗策略至关重要。本文旨在综述二者的发展历程、MetS各组分与CMD之间的关系、疾病诊疗以及未来研究方向,以期为临床提供借鉴。

关键词: 冠状动脉心脏病, 冠状动脉微循环障碍, 代谢综合征, 综述, 述评

Abstract:

Coronary microvascular dysfunction (CMD) and metabolic syndrome (MetS) have attracted much attention recently due to the adverse effects on cardiovascular system. CMD is a potential factor leading to myocardial ischemia, which is closely related to the occurrence, progression and poor prognosis of cardiovascular diseases. MetS is a group of metabolic diseases caused by a combination of genetic and environmental factors. There is an association between CMD and MetS, understanding the complex interactions between the two diseases is essential for developing effective prevention and treatment strategies. This article aims to review the development of MetS and CMD, and the relationship of the components of MetS with CMD, as well as the diagnosis, treatment and future research directions of these diseases.

Key words: Coronary heart diseases, Coronary microvascular dysfunction, Metabolic syndrome, Review, Editorial