关键词: 糖尿病前期, 焦虑, 情绪, 影响因素分析, 调查研究

Abstract: Background　At present，there may be as many as 113.9 million adult diabetic patients and nearly 500 million pre-diabetic patients in China.The prevalence of anxiety in diabetic patients is 40%，which is much higher than that in healthy people.However，there are few studies on anxiety in pre-diabetic patients.Objective　To clarify the anxiety status of pre-diabetic patients through the investigation and analysis of anxiety in pre-diabetic patients，and analyze its influential factors，so as to provide scientific basis for psychological intervention of pre-diabetic patients.Methods　A total of 100 pre-diabetic patients screened by oral glucose tolerance test （OGTT） from March to September 2015 in the outpatient of endocrinology or physical examination department of Jiangxi Provincial People's Hospital were selected as the research objects.The self-designed questionnaire about general situation and self-rating anxiety scale （SAS） were used to carry out the questionnaire survey，and the clinical indicators were tested.According to the results of SAS score，subjects were divided into non anxiety group and anxiety group.The differences between the two groups were compared.The influential factors of anxiety in pre-diabetic patients were analyzed by multivariate logistic regression.Results　Atotal of 100 questionnaires were distributed and 100 valid questionnaires were collected，with the valid rate of 100.0%.There were 22 patients （22.0%）in the anxiety group，including 20 patients （90.9%）were mild anxiety，2 patients （9.1%）were moderate anxiety，and there were 78 patients （78.0%）in the non anxiety group．There were significant differences in monthly income and body mass index（BMI）between the two groups（P<0.05）．Anxiety was negatively correlated with family monthly income（rs=-0.256，P<0.05），and had no linear correlation with sex（rs=0.026），age（rs=-0.160），education level（rs=0.100），types of medical insurance（rs=0.140），BMI（rs=0.142），smoking （rs=0.095），alcohol consumption（rs=0.027），carotid atherosclerosis （rs=0.167），lower extremity atherosclerosis（rs=0.077），family history of diabetes（rs=0.049），hypertension（rs=0.061），hyperlipidemia （rs=0.032），FPG（rs=0.122），2 hPG（rs=0.034），HbA1c（rs=0.121，P>0.05）．Multivariate logistic regression analysis showed that family monthly income 〔OR=1.636，95%CI（1.010，2.648）〕was the influential factor of anxiety in pre-diabetic patients（P=0.045）．Conclusion　Anxiety is prevalent in pre-diabetic patients，and family monthly income is the main factor influencing their emotions.Therefore，doctors should pay attention to patients with relatively poor economic conditions，strengthen early screening and early intervention measures.

Key words: Prediabetic state, Anxiety, Emotions, Root cause analysis, Investigation