关键词: 代谢综合征, 超声检查,多普勒,彩色, 双肾下极脂肪囊面积, 胰岛素抵抗

Abstract: Objective　To investigate the relationship between color Doppler ultrasound measured the area of the inferior pole of the perirenal fat（AIPPF） and insulin resistance index of homeostasis model assessment（HOMA-IR） among patients with metabolic syndrome（MS）.Methods　From April 2008 to April 2009，72 cases who met the diagnostic criteria of MS from physical examination center of Yinzhou People’s Hospital，were selected as study subjects. Body mass index（BMI），waist circumference and biochemical indicators were measured，AIPPF and IAF were measured by color Doppler ultrasound，VAT was measured by magnetic resonance imaging（MRI）.The correlation between clinical/laboratory parameters and HOMA-IR was analyzed by Pearson correlation analysis and stepwise linear regression analysis.Results　For 72 patients with MS，the mean age was （49.0±9.2）years old，the mean stature was（165.8±8.8） cm，the mean body mass was（75.8±10.6）kg，the mean BMI was（27.6±2.9） kg/m2，the mean waist circumference was（95.8±8.4） cm，the mean level of fasting blood glucose was（6.3±0.9） mmol/L，the mean level of fasting insulin was（15.4±10.1） mU/L，the mean HOMA-IR was （1.2±0.7），the mean AIPPF was （10.2±2.8）cm2，the mean IAF was （10.0±0.9）cm，the mean VAT was （112.6±15.5）cm2. According to Pearson correlation analysis results，there were no linear correlation between age，height，and HOMA-IR（P>0.05），and there were positive correlation between body mass，BMI，waist circumference，fasting blood glucose level，fasting insulin level，AIPPF，IAF，VAT and HOMA-IR（P<0.05）. Stepwise linear regression analysis results showed that AIPPF，age and BMI entered the regression equation，the regression equation was HOMA-IR=-0.493+0.001 AIPPF-0.20 age+0.51 BMI，the difference was statistically significant（F=16.155，P<0.001）.Conclusion　AIPPF is significantly related to HOMA-IR among patients with MS.

Key words: Metabolic syndrome, Ultrasonography, Doppler, color, AIPPF, Insulin resistance