关键词: 潜在不当用药清单, 潜在不适当用药, 目录, 老年人, 合理用药, 中国, 解读

Abstract: The potentially inappropriate medications (PIM)-China criteria is a screening tool to assess the extent of PIM in aged patients. 2024 PIMChina criteria are the second revision of the criteria since its establishment, aiming to ensure the provision of evidence-based and clinically relevant recommendations for the elderly. This article provides a detailed interpretation of the updated version of the criteria. The new criteria divided into two main parts, which is same as the framework of the 2017 PIM-China criteria. It references six international standards and incorporates substantial updates [Beers、STOPP、FORTA、EU（7）-PIM、Japanese and Korean Standards] based on the latest evidence-based medicine. The new criteria involve the adding of alternative treatment options, as well as the quality of evidence and the strength of recommendation. Moreover, drug-drug interactions and dose adjustments based on renal function were added. Meanwhile, some medications or criteria removed from the 2017 PIM-China criteria according to the actual clinical practice in China. By integrating emerging evidence and expert consensus, the new criteria serve as a pivotal tool for optimizing clinical prescribing practices. These criteria are crucial for reducing adverse drug events, optimizing prescription practices, and improving healthcare for the elderly in China.

Key words: Potentially inappropriate medication list, Potentially inappropriate medication, Contents, Aged, Rational drug use, China, Interpretation