Vaccine-preventable diseases impose a significant health burden on adults in China, highlighting urgent needs to address gaps in the current adult immunization program. The Expert Consensus on Health Promotion Strategies for Adult Vaccination in China was developed through collaboration among experts from multiple institutions, led by the Institute for Healthy China, Tsinghua University, School of Public Health, Peking University, College of General Practice, Southern University of Science and Technology, and the Public Health Security and Health Professional Committee, Public Safety Science and Technology Society. Integrating evidence-based scientific research and practical insights from multidisciplinary experts in immunization promotion, this consensus addresses the necessity and health value of adult vaccination, the current status and challenges of adult vaccination services in China, and expert recommendations for advancing strategies such as integrating medical and preventive care, promoting vaccine prescriptions by general practitioners, and developing a national adult immunization strategy. The consensus aims to provide scientific, systematic, and actionable guidance for government policymakers, public health agencies, healthcare providers, and health promotion practitioners to facilitate vaccination efforts for key adult groups from a life-cycle perspective.