中国全科医学 ›› 2022, Vol. 25 ›› Issue (11): 1368-1372.DOI: 10.12114/j.issn.1007-9572.2021.01.416

所属专题: 精神卫生最新文章合集

• 论著 • 上一篇    下一篇

体质指数在焦虑症与抑郁症关系中的调节效应研究

田洋丽1,2, 杨肇熙3, 张剑昭1, 邹晓伟1,2, 冯基高1, 朱博1, 万爱兰1,*   

  1. 1330006 江西省南昌市,南昌大学第一附属医院心身医学科
    2330031 江西省南昌市,南昌大学公共管理学院
    3518107 广东省深圳市光明区妇幼保健院儿童保健科
  • 收稿日期:2021-12-24 修回日期:2022-01-25 出版日期:2022-04-15 发布日期:2022-03-28
  • 通讯作者: 万爱兰
  • 基金资助:
    江西省学位与研究生教育教学改革研究项目(JXYJG-2019-033)

Study on the Moderating Effect of Body Mass Index in Correlation of Anxiety and Depression Disorders

TIAN Yangli12YANG Zhaoxi3ZHANG Jianzhao1ZOU Xiaowei12FENG Jigao1ZHU Bo1WAN Ailan1*   

  1. 1.Department of Psychosomatic Medicinethe First Affiliated Hospital of Nanchang UniversityNanchang 330006China

    2.School of Public AdministrationNanchang UniversityNanchang 330031China

    3.Department of Child HealthcareMaternal and Child Health Hospital of Shenzhen Guangming DistrictShenzhen 518107China

    *Corresponding authorWAN AilanChief physicianProfessorE-mail903594921@qq.com

  • Received:2021-12-24 Revised:2022-01-25 Published:2022-04-15 Online:2022-03-28

摘要: 背景焦虑症与抑郁症同属精神类疾病,单一焦虑症或抑郁症患者随病情进展会高概率出现"焦虑-抑郁共病"现象,但目前预防两种疾病发展成"共病"及解决二者"共病"的相关研究较少。目的探讨焦虑症与抑郁症之间的相关性,以及体质指数(BMI)在二者相关性中的调节效应。方法采用简单随机抽样法抽取2021-06-01至2021-08-31南昌大学第一附属医院门诊部和住院部收治的86例焦虑症患者为研究对象。采用自编人口学问卷调查患者一般人口学特征,采用汉密尔顿焦虑量表、汉密尔顿抑郁量表评估患者焦虑症及抑郁症严重程度。焦虑症与抑郁症、焦虑症与BMI、抑郁症与BMI的相关性分析采用Pearson相关分析;采用分层回归分析探究BMI在焦虑症与抑郁症中的调节效应。结果共80例患者符合纳入与排除标准且被同时诊断为抑郁症。患者焦虑症与抑郁症呈正相关(r=0.70,P<0.01);BMI与焦虑症无线性相关(r=0.03,P>0.05);BMI与抑郁症无线性相关(r=0.14,P>0.05);BMI调节了焦虑症与抑郁症之间的相关性(β=-0.16,P<0.01)。结论BMI可以减弱焦虑症对抑郁症的影响,有助于预防二者发展成共病性精神障碍,为未来制定新的饮食标准或运动模式进行心理健康预防和治疗提供新思路,在一定程度上拓展营养精神病学的研究领域。

关键词: 焦虑症, 抑郁症, 人体质量指数, 数据相关性, 调节效应

Abstract: Background

As two different kinds of mental disorders, anxiety disorder and depressive disorder could probably coexist in one with the proceeding of the illness. However, there are few studies on how to prevent and treat the coexistence of anxiety and depressive disorders.

Objective

To discuss the relationship between anxiety and depressive disorders, and the moderating effect of body mass index (BMI) in their relationship.

Methods

By use of simple random sampling, 86 outpatients and inpatients with anxiety disorders were selected from the First Affiliated Hospital of Nanchang University during June 1st to August, 31st, 2021. A self-made demographic questionnaire was used to obtain the demographic information. The Hamilton Anxiety Rating Scale was used to assess the anxiety level. The Hamilton Rating Scale for Depression was used to assess the depression level. Pearson correlation analyses were performed to assess the relationship between anxiety and depression disorders, and that between BMI and anxiety or depression disorder. Hierarchical regression analysis was adopted to explore the moderating effect of BMI on the relationship between anxiety and depressive disorders.

Results

Eighty eligible cases were also diagnosed with depression. The anxiety prevalence was significantly increased with depression prevalence (r=0.70, P<0.01) . BMI had no significant linear correlation with anxiety prevalence (r=0.03, P>0.05) . BMI also had no significant linear correlation with depression prevalence (r=0.14, P>0.05) . BMI moderated the relationship between anxiety and depression disorders significantly (β=-0.16, P<0.01) .

Conclusion

BMI can weaken the effect of anxiety disorder on depression, helping prevent them from developing into comorbid mental disorders, providing new ideas for developing new dietary standard or exercise patterns for mental health prevention and treatment in the future and expands the research field of nutritional psychiatry to a certain extent.

Key words: Anxiety disorders, Depression disorders, Body mass index, Correlation of data, Regulatory effect

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