中国全科医学 ›› 2020, Vol. 23 ›› Issue (6): 662-666.DOI: 10.12114/j.issn.1007-9572.2019.00.627

• 专题研究 • 上一篇    下一篇

社区糖尿病患者大肠癌筛查结果分析

杨军花1,张玮1*,杨安卿2,秦征魏1,刘岩1,花云1,华红梅1,郭稀1   

  1. 1.200063上海市白玉社区卫生服务中心 2.200025上海市,上海交通大学医学院附属瑞金医院卢湾分院
    *通信作者:张玮,副主任医师;E-mail:cntscsm@163.com
  • 出版日期:2020-02-20 发布日期:2020-02-20
  • 基金资助:
    上海市普陀区卫生系统自主创新科研资助项目(社区项目2018-10)

Screening Results Analysis of Colorectal Cancer in Diabetic Patients in Communities 

YANG Junhua1,ZHANG Wei1*,YANG Anqing2,QIN Zhengwei1,LIU Yan1,HUA Yun1,HUA Hongmei1,GUO Xi1   

  1. 1.Baiyu Community Health Service Center,Shanghai 200063,China
    2.Luwan Branch,Ruijin Hospital Affiliated to Medical College of Shanghai Jiaotong University,Shanghai 200025,China
    *Corresponding author:ZHANG Wei,Associate chief physician;E-mail:cntscsm@163.com
  • Published:2020-02-20 Online:2020-02-20

摘要: 背景 随着现代生活方式的改变,糖尿病和大肠癌发病率均呈逐渐上升趋势。糖尿病与大肠癌的相关性研究证明,糖尿病是大肠癌的高危因素,该人群应定期进行大肠癌筛查。目的 分析糖尿病患者参与大肠癌筛查的结果,为今后社区糖尿病慢性病管理工作提供更多的技术参考。方法 选取2016—2018年上海市白玉社区卫生服务中心所辖社区中参与大肠癌筛查的糖尿病患者319例,研究初期发放两份调查问卷表,一份是基于体检要求本中心自行设计的健康体检表,主要调查参与筛查的居民有无确诊糖尿病史。另一份为上海市大肠癌筛查项目组统一编制的《上海市社区居民大肠癌筛查危险度评估表》,内容包括基本情况(性别、年龄、婚姻状况、文化程度、职业)、大肠癌危险因素(慢性腹泻史、慢性便秘史、黏液血便史、慢性阑尾炎或阑尾切除史、慢性胆囊炎或胆囊切除史、肠息肉史、血吸虫病史、癌症史、一级亲属肿瘤史、精神创伤史),记录初筛结果(便隐血试验阳性、危险度评估阳性,任一阳性为初筛阳性)。研究后期针对初筛阳性者发放本中心自行编制的调查问卷表,内容包括是否行肠镜检查、肠镜检查结果、对肠镜检查相关认知(对肠镜检查害怕、认为自己不会有问题、担心检查后出现不适后果、担心查出问题有心理负担、没时间没兴趣、肠镜检查有益处)。结果 319例患者年龄以60~69岁居多(45.8%),婚姻状况以已婚为主(91.2%),文化程度以中专/中学为主(57.1%),职业以国有企业为主(39.8%)。大肠癌危险因素以慢性阑尾炎或阑尾切除史、肠息肉史、慢性胆囊炎或胆囊切除史占比较高,分别为14.7%、13.8%、13.5%。便隐血试验阳性率6.6%(21/319),危险度评估阳性率18.2%(58/319),双阳性率6.0%(19/319)。79例初筛阳性患者中,有23例进行了肠镜检查,其中无病变者占39.1%、肠炎者占26.1%、息肉者占21.7%。79例初筛阳性患者中39例认为肠镜检查有益处,22例对肠镜检查害怕。结论 约25%的社区糖尿病患者大肠癌初筛阳性,尤其关注有慢性阑尾炎或阑尾切除史、慢性胆囊炎或胆囊切除史、肠息肉史的患者。

关键词: 糖尿病, 肠肿瘤, 社区卫生中心, 筛查

Abstract: Background With the changes in modern lifestyles,the incidence of diabetes and colorectal cancer is increasing gradually.The study of the relationship between diabetes and colorectal cancer proves that diabetes is a high risk factor for colorectal cancer,and regular screening for colorectal cancer should be noted.Objective To analyze the results of patients with diabetes mellitus participating in colorectal cancer screening,and provide more technical references for the management of chronic diseases in community diabetes in the future.Methods 319 diabetic patients who participated in colorectal cancer screening in communities under the jurisdiction of Shanghai Baiyu community health service center from 2016 to 2018 were selected.Two questionnaires were issued at the beginning of the study.One was a health checklist designed by the center based on the requirements of the medical examination.The main purpose was to investigate whether the residents who participated in the screening had a history of diabetes mellitus.Another Shanghai Community Residents Colorectal Cancer Screening Risk Assessment Form prepared for screening for colorectal cancer in Shanghai included basic information(gender,age,marital status,education level,occupation) and risk factors of colorectal cancer(chronic diarrhea,history of chronic constipation,history of mucus and bloody stool,history of chronic appendicitis or appendectomy,history of chronic cholecystitis or cholecystectomy,history of intestinal polyps,history of schistosomiasis,history of cancer,history of first-degree relatives with cancer,history of trauma) and primary screening results(positive occult blood test,positive risk assessment,and any positive results for primary screening).In the later stage of the study,the questionnaires prepared by the center were distributed,its content included whether to have colonoscopy,colonoscopy results,and recognition related to colonoscopy (fear of colonoscopy,thinking that there will be no problem and worrying about the uncomfortable consequences after the examination,the psychological burden of finding out the problem,the lack of time and interest,and the benefit of colonoscopy).Results A total of 319 patients with diabetes were enrolled.The age ranged from 60 to 69 years old(45.8%).The marital status was mainly married (91.2%).The education level was mainly secondary specialized school/ secondary school (57.1%).State-owned enterprise was the mainstay occupation(39.8%).The risk factors of colorectal cancer were chronic appendicitis or history of appendectomy,history of intestinal polyps,and chronic cholecystitis or history of cholecystectomy,which were 14.7%,13.8%,and 13.5%,respectively.The positive rate of occult blood was 6.6%(21/319),the positive rate of risk assessment was 18.2%(58/319),and the double positive rate was 6.0%(19/319).There were 79 patients with positive screening and 23 patients underwent colonoscopy.Among them,patients with no lesion accounted for 39.1%,enteritis accounted for 26.1%,and polyps accounted for 21.7%.Of 79 patients who had positive screening results,39 were considered they could benefit from colonoscopy and 22 were afraid of colonoscopy.Conclusion About 25% of the community diabetes patients with colorectal cancer screening positive, especially pay attention to patients with history of chronic appendicitis or appendectomy, chronic cholecystitis or cholecystectomy, and intestinal polyp..

Key words: Diabetes mellitus, Intestinal neoplasms, Community health centers, Screening