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中国老年人骨质疏松症患病率的 Meta 分析
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朱洁云 ,高敏 ,宋秋韵 ,吉攀 ,李红园 ,钟枝梅 ,沈印 1* 扫描二维码
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【摘要】 背景 骨质疏松症(OP)的患病率高,且其患病率随着年龄的增长而逐渐增加,OP 及其引起的骨折
给患者家庭及社会造成沉重的经济负担,防治 OP 刻不容缓。了解我国 OP 的患病情况是开展 OP 防控工作的前提。
目的 通过 Meta 分析了解中国老年人 OP 的患病情况。方法 计算机检索 PubMed、中国知网(CNKI)、万方数据知
识服务平台和维普网(VIP)中关于中国老年人 OP 患病率相关的横断面研究,检索时限为 2000-01-01 至 2021-03-
20。提取数据并评价纳入研究的文献质量,采用 Stata 12.0 软件进行 Meta 分析。结果 共纳入 48 篇横断面研究,包含
68 932 例研究对象。Meta 分析结果显示,中国≥ 60 岁老年人 OP 患病率为 37.7%〔95%CI(33.8%,41.7%)〕。
亚组分析结果显示,2000—2009 年中国≥ 60 岁老年人 OP 患病率为 39.6%〔95%CI(33.4%,45.9%)〕,2010—
2020 年为 35.9%〔95%CI(31.1%,40.8%)〕;中国南方地区≥ 60 岁老年人 OP 患病率为 39.7%〔95%CI(34.0%,
45.5%)〕,中国北方地区为 35.7%〔95%CI(30.1%,41.2%)〕;中国男性≥ 60 岁老年人 OP 患病率为 27.3%〔95%CI
(23.9%,30.7%)〕,中国女性为 48.4%〔95%CI(42.7%,54.1%)〕;中国 60~69 岁老年人 OP 患病率为 32.2%〔95%CI
(28.6%,35.7%)〕,70~79 岁老年人为 41.9%〔95%CI(36.9%,46.9%)〕,≥ 80 岁老年人为 51.8%〔95%CI(43.9%,
59.7%)〕。结论 当前证据表明,中国老年人 OP 患病率为 37.7%,且随着年龄的增长逐渐上升。
【关键词】 骨质疏松;老年人;患病率;中国;Meta 分析
【中图分类号】 R 681 【文献标识码】 A DOI:10.12114/j.issn.1007-9572.2021.02.083
朱洁云,高敏,宋秋韵,等 . 中国老年人骨质疏松症患病率的 Meta 分析[J]. 中国全科医学,2022,25(3):
346-353. [www.chinagp.net]
ZHU J Y,GAO M,SONG Q Y,et al. Prevalence of osteoporosis in Chinese elderly people:a meta-analysis[J].
Chinese General Practice,2022,25(3):346-353.
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Prevalence of Osteoporosis in Chinese Elderly People: a Meta-analysis ZHU Jieyun ,GAO Min ,SONG Qiuyun ,JI
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Pan ,LI Hongyuan ,ZHONG Zhimei ,SHEN Yin 1*
1.International Medical Services,the People's Hospital of Guangxi Zhuang Autonomous Region,Nanning 530021,China
2.Department of General Medicine,the Second Affiliated Hospital of Guangxi Medical University,Nanning 530007,China
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Corresponding author:SHEN Yin,Chief physician;E-mail:sy_doctor@sina.cn
【Abstract】 Background The prevalence of osteoporosis is high and increases gradually with age. Osteoporosis and
its related fractures have exerted a heavy economic burden on patients' families,and the society,so it is urgent to prevent and
treat osteoporosis. Understanding osteoporosis prevalence is a prerequisite for containing osteoporosis in China. Objective To
understand osteoporosis prevalence in Chinese elderly people through a meta-analysis. Methods PubMed,CNKI,Wanfang
Data Knowledge Service Platform and VIP databases were searched to collect cross-sectional studies about osteoporosis prevalence
in Chinese elderly people published from January 1,2000 to March 20,2021. Data from eligible studies were extracted,and
methodological quality of these studies was assessed. Meta-analysis was performed by using Stata 12.0. Results A total of 48
studies involving 68 932 cases were included. Meta-analysis showed that the overall prevalence of osteoporosis in Chinese adults
aged ≥ 60 years was 37.7%〔95%CI(33.8%,41.7%)〕. Subgroup analyses indicated that osteoporosis prevalence in Chinese
adults aged ≥ 60 years was 35.9%〔95%CI(31.1%,40.8%)〕 from 2010 to 2020,while that was 39.6%〔95%CI(33.4%,
45.9%)〕 between 2000 and 2009. Osteoporosis prevalence in this age group in southern and northern China was 39.7%〔95%CI
(34.0%,45.5%)〕,and 35.7%〔95%CI(30.1%,41.2%)〕,respectively. Osteoporosis prevalence in men,and women
of this age group was 27.3%〔95%CI(23.9%,30.7%)〕 and 48.4%〔95%CI(42.7%,54.1%)〕,respectively. The
prevalence of osteoporosis in those aged 60-69,70-79,and over 80 was 32.2%〔95%CI(28.6%,35.7%)〕,41.9%〔95%CI
1.530021 广西壮族自治区南宁市,广西壮族自治区人民医院国际医疗部 2.530007 广西壮族自治区南宁市,广西医科大学第二
附属医院全科医学科
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通信作者:沈印,主任医师;E-mail:sy_doctor@sina.cn
本文数字出版日期:2021-10-28