Research Progress of Diagnostic Methods of Coronary Microvascular Dysfunction

doi:10.3969/j.issn.1007-9572.2016.26.023

Abstract

Abstract: Coronary microcirculation system plays an important role in myocardial blood flow,and its dysfunction may result in different degrees of coronary artery disease especially coronary heart disease,such as acute myocardial infarction with no or slow re-flow during emergency percutaneous interventional therapy and microvascular angina.The development of modern medicine has allowed new imaging technology to clearly display epicardial coronary arteries,but such technology cannot detect significantly small coronary arteries.Accurate discovery of coronary microvascular dysfunction is important for guiding cardiovascular disease treatment,improving clinical symptoms,and predicating prognosis.In recent years,many methods have been used to evaluate coronary microcirculation function,but none of these methods has been adopted as a golden standard.The present study reviews the research progress of these diagnosis methods.

Key words: Coronary circulation, Microvessels, Diagnosis, Review

摘要： 　　冠状动脉微血管在心肌血供中起重要作用，其功能障碍会导致不同程度的冠状动脉疾病，尤其是冠心病，如急性心肌梗死急诊介入术后无复流/慢血流现象、微血管性心绞痛等。随着现代医学的发展，新的影像技术可以清晰显示心外膜冠状动脉，但对微小冠状动脉却无能为力。准确发现冠状动脉微血管功能障碍对指导心血管疾病治疗，改善患者症状及预测预后有着积极的意义。近些年涌现了许多评价冠状动脉微血管功能障碍的方法，尚无金标准，本文现将这些诊断方法的研究进展综述如下。

关键词: 冠状动脉循环, 微血管, 诊断, 综述

XU Bing, HE Sheng-hu, XU Ri-xin, XIE Yong, JI Jun, LIAO Qing-chi, DENG Min, CHENG Cheng. Research Progress of Diagnostic Methods of Coronary Microvascular Dysfunction[J]. Chinese General Practice, 2016, 19(26): 3238-3242.

徐冰, 何胜虎, 徐日新, 谢勇, 纪军, 廖清池, 邓敏, 程铖. 冠状动脉微血管功能障碍诊断方法的研究进展[J]. 中国全科医学, 2016, 19(26): 3238-3242.

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