| [1] |
Wang L M, Peng W, Zhao Z P, et al. Prevalence and treatment of diabetes in China, 2013-2018[J]. JAMA, 2021, 326(24): 2498-2506. DOI: 10.1001/jama.2021.22208.
|
| [2] |
Genitsaridi I, Salpea P, Salim A, et al. 11th edition of the IDF Diabetes Atlas: global, regional, and national diabetes prevalence estimates for 2024 and projections for 2050[J]. Lancet Diabetes Endocrinol, 2026, 14(2): 149-156. DOI: 10.1016/S2213-8587(25)00299-2.
|
| [3] |
Partridge L, Deelen J, Slagboom P E. Facing up to the global challenges of ageing[J]. Nature, 2018, 561(7721): 45-56. DOI: 10.1038/s41586-018-0457-8.
|
| [4] |
World Health Organization. PHC: now more than ever[R]. Geneva: World Health Organization, 2008.
|
| [5] |
Feinstein A R. The pre-therapeutic classification of co-morbidity in chronic disease[J]. J Chronic Dis, 1970, 23(7): 455-468. DOI: 10.1016/0021-9681(70)90054-8.
|
| [6] |
Afshar S, Roderick P J, Kowal P, et al. Multimorbidity and the inequalities of global ageing: a cross-sectional study of 28 countries using the World Health Surveys[J]. BMC Public Health, 2015, 15: 776. DOI: 10.1186/s12889-015-2008-7.
|
| [7] |
|
| [8] |
Salisbury C, Man M S, Bower P, et al. Management of multimorbidity using a patient-centred care model: a pragmatic cluster-randomised trial of the 3D approach[J]. Lancet, 2018, 392(10141): 41-50. DOI: 10.1016/S0140-6736(18)31308-4.
|
| [9] |
Sinclair A J, Abdelhafiz A H, Rodríguez-Mañas L. Frailty and sarcopenia - newly emerging and high impact complications of diabetes[J]. J Diabetes Complications, 2017, 31(9): 1465-1473. DOI: 10.1016/j.jdiacomp.2017.05.003.
|
| [10] |
Ryan A, Wallace E, O'Hara P, et al. Multimorbidity and functional decline in community-dwelling adults: a systematic review[J]. Health Qual Life Outcomes, 2015, 13: 168. DOI: 10.1186/s12955-015-0355-9.
|
| [11] |
滕晋,王丹,徐熙, 等. 老年患者多重用药调查及共病管理的临床策略[J]. 中国卫生事业管理, 2015, 32(9): 695-697.
|
| [12] |
Lee J E, Lee J, Shin R, et al. Treatment burden in multimorbidity: an integrative review[J]. BMC Prim Care, 2024, 25(1): 352. DOI: 10.1186/s12875-024-02586-z.
|
| [13] |
|
| [14] |
Duncan P, Murphy M, Man M S, et al. Development and validation of the multimorbidity treatment burden questionnaire (MTBQ)[J]. BMJ Open, 2020, 8(4): e019413. DOI: 10.1136/bmjopen-2017-019413.
|
| [15] |
May C, Montori V M, Mair F S. We need minimally disruptive medicine[J]. BMJ, 2009, 339(aug11 2): b2803. DOI: 10.1136/bmj.b2803.
|
| [16] |
Eton D T, Ramalho de Oliveira D, Egginton J S, et al. Building a measurement framework of burden of treatment in complex patients with chronic conditions: a qualitative study[J]. Patient Relat Outcome Meas, 2012, 3: 39-49. DOI: 10.2147/PROM.S34681.
|
| [17] |
|
| [18] |
Zhang D X, Sit R W S, Wong C, et al. Cohort profile: The prospective study on Chinese elderly with multimorbidity in primary care in Hong Kong[J]. BMJ Open, 2020, 10(2): e027279. DOI: 10.1136/bmjopen-2018-027279.
|
| [19] |
Eton D T, Lee M K, St Sauver J L, et al. Known-groups validity and responsiveness to change of the Patient Experience with Treatment and Self-management (PETS vs. 2.0): a patient-reported measure of treatment burden[J]. Qual Life Res, 2020, 29(11): 3143-3154. DOI: 10.1007/s11136-020-02546-x.
|
| [20] |
Pearson-Stuttard J, Holloway S, Polya R, et al. Variations in comorbidity burden in people with type 2 diabetes over disease duration: a population-based analysis of real world evidence[J]. EClinicalMedicine, 2022, 52: 101584. DOI: 10.1016/j.eclinm.2022.101584.
|
| [21] |
Hu X J, Wang H H X, Li Y T, et al. Healthcare needs, experiences and treatment burden in primary care patients with multimorbidity: an evaluation of process of care from patients' perspectives[J]. Heal Expect, 2022, 25(1): 203-213. DOI: 10.1111/hex.13363.
|
| [22] |
|
| [23] |
Lin K, Yao M, Andrew L, et al. Exploring treatment burden in people with type 2 diabetes mellitus: a thematic analysis in China's primary care settings[J]. BMC Prim Care, 2024, 25(1): 88. DOI: 10.1186/s12875-024-02301-y.
|
| [24] |
Xu Z J, Zhang D X, Zhao Y, et al. The Chinese version of patient experience with treatment and self-management (PETS vs. 2.0): translation and validation in patients with multimorbidity in primary care in Hong Kong[J]. J Patient Rep Outcomes, 2024, 8(1): 82. DOI: 10.1186/s41687-024-00765-1.
|
| [25] |
Jia Z H, Niu Z M, Wang J J, et al. Trajectories of treatment burden among primary care patients with long-term conditions in Southern China: a latent class growth analysis[J]. Risk Manag Healthc Policy, 2024, 17: 2009-2021. DOI: 10.2147/RMHP.S464434.
|
| [26] |
Ho I S S, Azcoaga-Lorenzo A, Akbari A, et al. Measuring multimorbidity in research: Delphi consensus study[J]. BMJ Med, 2022, 1(1): e000247. DOI: 10.1136/bmjmed-2022-000247.
|
| [27] |
Eremenco S L, Cella D, Arnold B J. A comprehensive method for the translation and crosscultural validation of health status questionnaires[J]. Eval Health Professions, 2025, 28(2):212-232. DOI: 10.1177/0163278705275342.
|
| [28] |
|
| [29] |
Boye K S, Mody R, Lage M J, et al. Chronic medication burden and complexity for US patients with type 2 diabetes treated with glucose-lowering agents[J]. Diabetes Ther, 2020, 11(7): 1513-1525. DOI: 10.1007/s13300-020-00838-6.
|
| [30] |
Aramrat C, Choksomngam Y, Jiraporncharoen W, et al. Advancing multimorbidity management in primary care: a narrative review[J]. Prim Health Care Res Dev, 2022, 23: e36. DOI: 10.1017/S1463423622000238.
|
| [31] |
Zelko E, Klemenc-Ketis Z, Tusek-Bunc K. Medication adherence in elderly with polypharmacy living at home: a systematic review of existing studies[J]. Mater Sociomed, 2016, 28(2): 129-132. DOI: 10.5455/msm.2016.28.129-132.
|
| [32] |
Eton D T, Yost K J, Lai J S, et al. Development and validation of the Patient Experience with Treatment and Self-management (PETS): a patient-reported measure of treatment burden[J]. Qual Life Res, 2017, 26(2): 489-503. DOI: 10.1007/s11136-016-1397-0.
|
| [33] |
Espinoza P, Varela C A, Vargas I E, et al. The burden of treatment in people living with type 2 diabetes: a qualitative study of patients and their primary care clinicians[J]. PLoS One, 2020, 15(10): e0241485. DOI: 10.1371/journal.pone.0241485.
|
| [34] |
Idiculla J, Advika T S, Kumari S. Exercise in patients with type 2 diabetes: Facilitators and barriers-a qualitative study[J]. J Family Med Prim Care, 2017, 6(2): 288. DOI: 10.4103/2249-4863.219998.
|
| [35] |
Li-Geng T, Kilham J, McLeod K M. Cultural influences on dietary self-management of type 2 diabetes in East Asian Americans: a mixed-methods systematic review[J]. Health Equity, 2020, 4(1): 31-42. DOI: 10.1089/heq.2019.0087.
|
| [36] |
Mostafavi-Darani F, Zamani-Alavijeh F, Mahaki B, et al. Exploring the barriers of adherence to dietary recommendations among patients with type 2 diabetes: a qualitative study in Iran[J]. Nurs Open, 2020, 7(6): 1735-1745. DOI: 10.1002/nop2.558.
|
| [37] |
|
| [38] |
Rosbach M, Andersen J S. Patient-experienced burden of treatment in patients with multimorbidity-a systematic review of qualitative data[J]. PLoS One, 2017, 12(6): e0179916. DOI: 10.1371/journal.pone.0179916.
|
| [39] |
Zhou F W, Xu C M, Sun Y X, et al. Influencing factors of outpatients' satisfaction in China a cross-sectional study of 16 public tertiary hospitals[J]. Patient Prefer Adherence, 2021, 15: 1243-1258. DOI: 10.2147/PPA.S311786.
|
| [40] |
Sun J, Lin Q, Zhao P Y, et al. Reducing waiting time and raising outpatient satisfaction in a Chinese public tertiary general hospital-an interrupted time series study[J]. BMC Public Heal, 2017, 17(1): 668. DOI: 10.1186/s12889-017-4667-z.
|
| [41] |
Li C L, Chen Z, Khan M M. Bypassing primary care facilities: health-seeking behavior of middle age and older adults in China[J]. BMC Heal Serv Res, 2021, 21(1): 895. DOI: 10.1186/s12913-021-06908-0.
|
| [42] |
Gong F F, Luo J X, Wang Z H, et al. Network characteristics of referrals for chronic disease patients: results from hierarchical medical reform in Shenzhen, China[J]. BMC Public Heal, 2024, 24(1): 3600. DOI: 10.1186/s12889-024-21175-4.
|
| [43] |
|
| [44] |
|
| [45] |
国家卫生健康委. 对十四届全国人大三次会议第4503号建议的答复[EB/OL]. (2025-07-03)[2026-01-09].
|
| [46] |
国家卫生健康委办公厅,国家医保局办公室. 关于印发长期处方管理规范(试行)的通知:国卫办医发〔2021〕17号[J]. 中华人民共和国国家卫生健康委员会公报, 2021(8): 4-7.
|
| [47] |
N'Goran A A, Pasquier J, Deruaz-Luyet A, et al. Factors associated with health literacy in multimorbid patients in primary care: a cross-sectional study in Switzerland[J]. BMJ Open, 2018, 8(2): e018281. DOI: 10.1136/bmjopen-2017-018281.
|
| [48] |
Pathirana T I, Jackson C A. Socioeconomic status and multimorbidity: a systematic review and meta-analysis[J]. Aust N Z J Public Heal, 2018, 42(2): 186-194. DOI: 10.1111/1753-6405.12762.
|
| [49] |
Morris J E, Roderick P J, Harris S, et al. Treatment burden for patients with multimorbidity: cross-sectional study with exploration of a single-item measure[J]. Br J Gen Pract, 2021, 71(706): e381-e390. DOI: 10.3399/bjgp.2020.0883.
|
| [50] |
Remelli F, Ceresini M G, Trevisan C, et al. Prevalence and impact of polypharmacy in older patients with type 2 diabetes[J]. Aging Clin Exp Res, 2022, 34(9): 1969-1983. DOI: 10.1007/s40520-022-02165-1.
|
| [51] |
Yang R M, Gao S Y, Jiang Y. Digital divide as a determinant of health in the U.S. older adults: prevalence, trends, and risk factors[J]. BMC Geriatr, 2024, 24(1): 1027. DOI: 10.1186/s12877-024-05612-y.
|
| [52] |
Wang Y D, Zhang Y P, Guo T T, et al. Knowledge level and health information-seeking behavior of people with diabetes in rural areas: a multicenter cross-sectional study[J]. Front Public Health, 2024, 12: 1285114. DOI: 10.3389/fpubh.2024.1285114.
|
| [53] |
|
| [54] |
|
| [55] |
Williams E H, Juarez L D, Presley C A, et al. Associations between suboptimal social determinants of health and diabetes distress in low-income patients on Medicaid[J]. J Gen Intern Med, 2025, 40(10): 2330-2336. DOI: 10.1007/s11606-025-09367-z.
|
| [56] |
|
| [57] |
Wang X, Sun X, Birch S, et al. People-centred integrated care in urban China[J]. Bulletin of the World Health Organization, 2018, 96(12): 843-852. DOI: 10.2471/BLT.18.214908.
|
| [58] |
|
| [59] |
|
| [60] |
|
| [61] |
Li M Y, Zhang X T, Tang H Q, et al. Quality of primary health care for chronic diseases in low-resource settings: evidence from a comprehensive study in rural China[J]. PLoS One, 2024, 19(7): e0304294. DOI: 10.1371/journal.pone.0304294.
|