关键词: Crohn病, 腹痛, 面部肿胀, 肺疾病　

Abstract: Crohn's disease is a chronic granulomatous disease with unknown etiology involving the small intestine and ileocecal region.Some patients had parenteral manifestations.The extraintestinal manifestations of Crohn's disease may involve various systems，but there are no reports of facial swelling.A case of Crohn's disease with parenteral manifestations，including right lower abdominal pain，facial swelling and pulmonary lesions，was reported in this paper.Literature review was also carried out.We suggested that attention should be paid to the differential diagnosis between Melkersson's Rosenthal syndrome and oral-facial granulomatosis，both of which were related to the clinic and pathology of Crohn's disease.Secondly，attention should be paid to pulmonary lesions caused by drugs （mesalazine or sulfasalazine） so as to increase clinicians' understanding of Crohn's disease complicated with parenteral manifestations.

Key words: Crohn disease, Abdominal pain, Facial swelling, Lung diseases