中国全科医学 ›› 2022, Vol. 25 ›› Issue (15): 1906-1909.DOI: 10.12114/j.issn.1007-9572.2022.02.019

• 典型病例研究 • 上一篇    下一篇

以巨大足部溃疡为表现的坏疽性脓皮病伴克罗恩病一例报道并文献复习

黄虹玉1,2, 雷甜甜3, 马洪升3, 胡仁伟1, 杨锦林1,2,*()   

  1. 1. 610041 四川省成都市,四川大学华西医院消化内科
    2. 610041 四川省成都市,四川大学-牛津大学华西消化道肿瘤联合研究中心
    3. 610041 四川省成都市,四川大学华西医院日间服务中心
  • 收稿日期:2021-11-12 修回日期:2022-01-20 出版日期:2022-01-27 发布日期:2022-01-27
  • 通讯作者: 杨锦林
  • 黄虹玉,雷甜甜,马洪升,等.以巨大足部溃疡为表现的坏疽性脓皮病伴克罗恩病一例报道并文献复习[J].中国全科医学,2022,25(15):1906-1909. [www.chinagp.net]
    作者贡献:黄虹玉提出研究选题方向,负责病例资料的收集和整理,并撰写论文初稿;雷甜甜进行病例资料的收集和整理;马洪升负责论文的修订;胡仁伟负责患者的诊治和病例资料的提供;杨锦林负责文章的质量控制及审校,对文章整体负责;所有作者确认了论文的最终稿。
  • 基金资助:
    国家自然科学基金资助项目(82173253)

Pyoderma Gangrenosum with Crohn's Disease Presenting as a Giant Foot Ulcer: a Case Report and Literature Review

Hongyu HUANG1,2, Tiantian LEI3, Hongsheng MA3, Renwei HU1, Jinlin YANG1,2,*()   

  1. 1. Department of Gastroenterology & Hepatology, West China Hospital of Sichuan University, Chengdu 610041, China
    2. Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre, Chengdu 610041, China
    3. Department of Day Surgery, West China Hospital of Sichuan University, Chengdu 610041, China
  • Received:2021-11-12 Revised:2022-01-20 Published:2022-01-27 Online:2022-01-27
  • Contact: Jinlin YANG
  • About author:
    HUANG H Y, LEI T T, MA H S, et al. Pyoderma gangrenosum with Crohn's disease presenting as a giant foot ulcer: a case report and literature review[J]. Chinese General Practice, 2022, 25 (15) : 1906-1909.

摘要: 足部溃疡可由多种病因导致,明确其病因对于治疗及预后至关重要。坏疽性脓皮病(PG)是一种少见的嗜中性皮病,且常伴系统性疾病,起病初期表现为炎性丘疹或脓疱,后迅速进展为疼痛性溃疡,易与局部感染性疾病、糖尿病足等混淆,但治疗方案完全不同。因此,临床早期及时诊断至关重要。本文报道了1例以巨大足部溃疡为表现的坏疽性脓皮病伴克罗恩病患者的诊治过程,并进行文献复习,以提高临床医生对此病的认识,减少误诊、误治。

关键词: 坏疽性脓皮病, 皮肤疾病, Crohn病, 炎性肠疾病, 足溃疡, 病例报告

Abstract:

Foot ulcers can be caused by a variety of causes, and identifying the causes is essential for treatment and prognosis. Pyoderma gangrenosum is an uncommon neutrophilic dermatosis that often accompanied by systemic diseases. The initial lesions of pyoderma gangrenosum is inflammatory papules or pustules, which rapidly progress to painful ulcers. Pyoderma gangrenosum are easily confused with local infectious diseases and diabetic feet, but the treatment options are completely different. Therefore, early and rapid diagnosis is crucial. This article reported on the diagnosis and treatment of a patient with pyoderma gangrenosum in association with Crohn's disease presenting as a giant foot ulcer, and reviewed the literature to improve clinicians' understanding of the disease and reduce misdiagnosis and mistreatment.

Key words: Pyoderma gangrenosum, Skin diseases, Crohn disease, Inflammatory bowel diseases, Foot ulcer, Case reports