关键词: 粪肠球菌, 粪菌移植, 肠道细菌, 难辨梭菌, 胃肠疾病

Abstract: Fecal microbiota transplantation （FMT） is the transfer of fecal bacteria from a healthy donor into the colon of a patient whose disease is a result of an altered microbiome，with the goal of restoring the normal microbiota and thus curing the disease.We mainly reviewed and summarized the clinical application of FMT recently：so far，sufficient evidences show that FMT is the most effective treatment for recurrent Clostridium difficile infection.Moreover，it is being exploratorily used as a potential therapy for other gastrointestinal diseases such as inflammatory bowel disease，irritable bowel syndrome and so on.Furthermore，although there is no adequate evidences supporting FMT for chronic fatigue syndrome，Parkinson's disease，metabolic disorders，multiple sclerosis and other non-gastrointestinal diseases，relevant studies are increasing rapidly. This article mainly reviewed the current evidences of clinical application of FMT.

Key words: Enterococcus faecalis, Fecal microbiota transplantation, Enteric bacteria, Clostridium difficile, Gastrointestinal diseases