关键词: 胸腺肿瘤, 胸腔镜, 疗效比较研究

Abstract: Objective　To compare the clinical efficacy of modified subxiphoid-subcostal approach with that of traditional transthoracic approach for the resection of thymic tumors（RTT）．Methods　The subjects enrolled in this study were 175 patients undergoing RTT in Department of Thoracic Surgery，Cangzhou Central Hospital from January 2013 to December 2017.95 of them receiving RTT via modified subxiphoid-subcostal approach and 80 via the traditional transthoracic approach were assigned to subxiphoid incision group and chest wall incision group，respectively.The clinical efficacy of these two approaches was compared from the duration of RTT，intraoperative blood loss，duration of postoperative chest tube drainage，length of stay，VAS score assessed on the 1st，3rd days after surgery，and incidence of postoperative complications.Results　Compared with the chest wall incision group，subxiphoid incision group demonstrated much shorter duration of RTT，duration of postoperative chest tube drainage and length of stay，significantly less intraoperative blood loss，obviously lower VAS score on the 1st，3rd days after surgery as well as notable lower incidence of postoperative complications（P<0.05）．Conclusion　RTT via the modified subxiphoid-subcostal approach is more simple to operate，requiring shorter duration.Moreover，it is contributive to smaller incision，lighter degree of postoperative pain，quicker recovery，shorter length of stay as well as lower incidence of postoperative complications among the patients.

Key words: Thymus neoplasms, Thoracoscopy, Comparative effectiveness research