关键词: 代谢综合征X, 诊断, 腰围, 腰臀比, 腰高比, 三酰甘油葡萄糖乘积指数

Abstract: Background　Metabolic syndrome（MS） is significantly associated with chronic diseases such as coronary heart disease and diabetes with an increasing prevalence year by year.However，the diagnostic criteria of MS are not uniform and the diagnostic conditions are complicated currently difficult for grassroots medical staff to operate.Objective　To compare the difference between the correlation of anthropometric indicators〔waist-to-height ratio（WHtR），waist-hip ratio（WHR），waist circumference（WC），and body mass index（BMI）〕，triglycerides glucose（TyG）index，triglyceride glucose-body mass index（TyG-BMI），and triglyceride glucose-waist circumference（TyG-WC） and MS，and its value in the diagnosis of MS in Chinese population，in order to determine the simple screening indicators of MS.Methods　The study was carried out with the participation of 2 972 adults who took the regular health check from Maizidian Village in Tongzhou District of Beijing.The questionnaire survey，physical examination，and blood examination were conducted to get their WHtR，WHR，BMI，TyG index，TyG-BMI and TyG-WC.MS patients were identified according to diagnostic criteria set by Chinese Diabetes Society（CDS）.SPSS 18.0 software was used to draw the ROC curves of the above indicators and calculate the AUC.The comparisons of AUCs were performed by MedCalc 16.8 software.Results　There was no significant difference in the prevalence of MS between different genders〔206/1 044 vs. 368/1 928，P>0.05〕.WHtR，WHR，WC，BMI，TyG index，TyG-BMI and TyG-WC were higher in patients with MS than those without（P<0.05）.The AUCs of BMI，WHtR，WHR and WC for male patients with MS were 0.81，0.77，0.68 and 0.77，and those for female patients with MS were 0.78，0.76，0.66 and 0.76.Comparing with WHtR，WHR and WC，the difference of AUC of BMI in diagnosing male and female patients with MS was higher（P<0.05）.The cut-off point of BMI for MS diagnosis was 25.00 kg/m2 for males and 25.30 kg/m2 for females.The AUCs of TyG index，TyG-BMI and TyG-WC in diagnosing male patients with MS were 0.88，0.89 and 0.88，and those for female patients with MS were 0.88，0.88 and 0.87.There was no significant difference in AUCs of TyG index and other two indexes in diagnosing MS（P>0.05）.The cut-off point of TyG index for MS diagnosis was 8.87 for males and 8.80 for females.The AUC of TyG index in male and female MS was higher than BMI（P<0.05）.Conclusion　Anthropometric indicators and TyG index and its related indicators are significantly associated with MS.BMI has a better correlation with MS than other anthropometric indicators which can be used to screen large-scale population for MS preliminarily.TyG index is better than BMI in the diagnosis of MS which can be used as a simple indicator for primary medical staff to identify risks of MS.

Key words:  , Metabolic syndrome X；Diagnosis；Waist circumference；Waist-hip ratio；Waist-to-height ratio；Trilyceridides glucose index