关键词: 卒中, 颅内动脉硬化, 支架, 预后

Abstract: Objective　To compare the vascular restenosis and treatment outcomes in patients with symptomatic intracranial atherosclerotic stenosis treated with either endovascular treatment or drug therapy，in order to provide a reference for preventing stroke recurrence and choosing optimal treatment plans.Methods　A total of 69 patients with symptomatic intracranial atherosclerotic stenosis treated in the Cangzhou People's Hospital between April 2015 and April 2017 were selected as study subjects.HR-MRI scanning was used to detect intracranial arterial stenosis，and TOF-MRA was used to reconstruct vascular structure and determine the location of stenosis.The patients voluntarily chose to be enrolled in the drug therapy group （37 cases）or endovascular treatment group（32 cases），in which drug therapy or intravascular stent implantation，respectively，were administered.Follow-up visits were conducted 1，2，3，and 6 months after surgery.The incidences of stroke，transient ischemic attack，and restenosis were recorded.Results　There were no deaths in both groups during the follow-up period.In the first month，there were no stroke and restenosis cases in the endovascular treatment group；while in the drug therapy group，there was one case each of stroke and restenosis，although the difference was not significant （P=1.000，1.000）．After the six months，the incidences of stroke and restenosis in the endovascular treatment group were 0 and 12.5% （4/32），respectively，in contrast to 16.2% （6/37） and 35.1% （13/37） in the drug therapy group；the difference was statistically significant （χ2=5.683，P=0.017；χ2=4.735，P=0.030）．Conclusion　Compared with drug therapy，endovascular treatment was associated with a lower incidence of stroke and restenosis in patients with symptomatic intracranial atherosclerotic stenosis.

Key words: Stroke, Intracranial arteriosclerosis, Stents, Prognosis