关键词: 免疫系统疾病, 木村病, 临床特点, 诊断, 治疗

Abstract: Kimura disease （KD） is a rare autoimmune-mediated chronic inflammatory disease that is common in young and middle aged men in Asia.The etiology and pathogenesis of the disease are unknown.Clinical misdiagnosis and mistreatment often occur on the basis of symptoms of painless single or multiple subcutaneous soft tissue masses in the head and neck，which can affect lymph nodes and salivary glands.Elevated blood eosinophils and serum immunoglobulin E levels is used to characterize the disease.Although the disease is a benign process for which surgery，radiotherapy and chemotherapy，and drug therapy are effective，the disease duration long，and the condition easily recurs.To investigate KD diagnosis and treatment，this article summarizes the diagnosis and treatment of four cases of KD diagnosed by pathological examination.In addition，a literature review of the clinical manifestations，pathological changes，diagnosis and treatment methods to improve the understanding of this rare disease，and to provide reference for its diagnosis and treatment，is presented.