中国全科医学 ›› 2016, Vol. 19 ›› Issue (28): 3506-3509.DOI: 10.3969/j.issn.1007-9572.2016.28.025

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缓解期炎性肠病伴肠易激综合征样症状机制的研究进展

曹明为,刘玉兰,马静静,等   

  1. 430060湖北省武汉市,武汉大学人民医院消化内科 通信作者:董卫国,430060湖北省武汉市,武汉大学人民医院消化内科;E-mail:dwg@whu.edu.cn
  • 出版日期:2016-10-05 发布日期:2026-01-15

Research Progress of Mechanism of Inflammatory Bowel Disease Patients with Irritable Bowel Syndrome-like Symptoms during Remission

CAO M W,LIU Y L,MA J J,et al   

  1. Department of Gastroenterology,Renmin Hospital of Wuhan University,Wuhan 430060,China Corresponding author:DONG Wei-guo,Department of Gastroenterology,Renmin Hospital of Wuhan University,Wuhan 430060,China;E-mail:dwg@whu.edu.cn
  • Published:2016-10-05 Online:2026-01-15

摘要: 炎性肠病(IBD)是一种病因不十分清楚的慢性非特异性肠道炎性疾病,缓解期IBD(IBDR)患者常伴有肠易激综合征(IBS)样症状。IBS样症状的存在导致患者的生活质量降低,影响医生对病情的评估及治疗策略的选择。因此,本文对IBDR患者伴有IBS样症状的机制进行综述,得出IBDR伴IBS样症状与肠道低度炎症和神经重塑均有关联,也可能为IBD合并了IBS。

关键词: 炎性肠疾病, 肠易激综合征, 炎症, 神经重塑

Abstract: Inflammatory bowel disease(IBD) is a chronic nonspecific inflammatory bowel disease with not very clear causes,IBD during remission(IBDR) patients often have irritable bowel syndrome(IBS)-like symptoms.The presence of IBS-like symptoms leads to reduced quality of life of patients,and influences assessment of disease and choice of treatment strategies of doctors.Therefore,the paper reviews the mechanism of IBDR patients with IBS-like symptoms,and concludes that IBDR with IBS-like symptoms was related to intestinal low-grade inflammation and nerve remodeling,and may also have combined IBS for IBD.

Key words: Inflammatory bowel diseases, Irritable bowel syndrome, Inflammation, Nerve remodeling