关键词: 肾小球肾炎, 膜性；特发性膜性肾病；中西医结合；中医药疗法；循证实践；诊疗指南

Abstract: In China, idiopathic membranous nephropathy (IMN) accounts for 24.9% of glomerular diseases, the second highest share, and is increasing year by year. Combined therapy of Chinese and Western medicine has been widely used in the clinical practice of IMN. However, there are no evidence-based practice guidelines for the treatment of IMN with integrated traditional Chinese and Western medicine.his guideline followed the methods and steps of the guideline development manual. The level of the body of the evidence was assessed by the GRADE. An outline of the clinical questions was formulated through interviews with leading Chinese medicine experts and a review of relevant clinical guidelines. Based on the results of a systematic review of authoritative textbooks and clinical research literature, a clinical question list, a clinical outcome assessment index for IMN, and a list of types of Chinese medicine syndromes were developed, and a national expert survey was conducted to identify the clinical questions included in this guideline. A systematic retrieval of evidence was conducted for the clinical questions included in the guideline, and its quality was assessed. Through an expert consensus meeting, 8 recommendations on the integrated traditional Chinese and Western medicine diagnosis and treatment for IMN were finalized. This guideline focuses on the clinical practice of integrated traditional Chinese and Western medicine in the diagnosis and treatment of IMN, and is applicable to healthcare workers who provide Chinese and Western medicine services.

Key words: Glomerulonephritis, membranous, Idiopathic membranous nephropathy, Integrated traditional Chinese and Western medicine, Chinese medicine therapy, Evidence-based practice, Diagnosis and treatment guideline