中国全科医学 ›› 2022, Vol. 25 ›› Issue (18): 2244-2248.DOI: 10.12114/j.issn.1007-9572.2022.0025

所属专题: 神经系统疾病最新文章合集

• 论著 • 上一篇    下一篇

城市地区40岁及以上存活脑卒中患者复发现状及其合并危险因素研究

焦诣珂1,2, 井丽1,2, 田园梦1,2, 郝新斌3, 王伟忠4, 宋程光5, 孙群6, 石雷7, 孙继绪8, 安晓霞9, 邢立莹1,2,*(), 杨佐森1,2,*()   

  1. 1.110005 辽宁省沈阳市,中国医科大学预防医学研究院
    2.110005 辽宁省沈阳市,辽宁省疾病预防控制中心慢病所
    3.111000 辽宁省辽阳市中心医院神经内科
    4.118000 辽宁省丹东市中心医院神经内科
    5.117000 辽宁省本溪市中心医院神经内科
    6.122000 辽宁省朝阳市疾病预防控制中心慢病科
    7.111000 辽宁省辽阳市疾病预防控制中心慢病科
    8.118000 辽宁省丹东市疾病预防控制中心慢病科
    9.117000 辽宁省本溪市疾病预防控制中心慢病科
  • 收稿日期:2021-11-20 修回日期:2022-03-15 出版日期:2022-06-20 发布日期:2022-04-21
  • 通讯作者: 邢立莹, 杨佐森
  • 焦诣珂,井丽,田园梦,等.城市地区40岁及以上存活脑卒中患者复发现状及其合并危险因素研究[J].中国全科医学,2022,25(18):2244-2248. [www.chinagp.net]
    作者贡献:焦诣珂提出研究思路及主要研究指标,负责研究的构思与设计、结果的分析与解释;郝新斌、王伟忠、宋程光、孙群、石雷、孙继绪、安晓霞进行数据收集、采集,指标化验与检测;焦诣珂、井丽进行数据整理,撰写论文;井丽、田园梦进行统计学处理;邢立莹、杨佐森负责文章的质量控制及审校,对文章整体负责,监督管理。
  • 基金资助:
    2019年辽宁省重点研发计划项目(2019JH2/10300001)

Recurrence Status and Combined Risk Factors of Surviving Stroke Patients Aged Over 40 in Urban Areas

Yike JIAO1,2, Li JING1,2, Yuanmeng TIAN1,2, Xinbin HAO3, Weizhong WANG4, Chengguang SONG5, Qun SUN6, Lei SHI7, Jixu SUN8, Xiaoxia AN9, Liying XING1,2,*(), Zuosen YANG1,2,*()   

  1. 1. Institute of Preventive Medicine, China Medical University, Shenyang 110005, China
    2. Chronic Non-communicable Disease Surveillance Institute, Liaoning Provincial Center for Disease Control and Prevention, Shenyang 110005, China
    3. Department of Neurology, Liaoyang Central Hospital, Liaoyang 111000, China
    4. Department of Neurology, Dandong Central Hospital, Dandong 118000, China
    5. Department of Neurology, Benxi Central Hospital, Benxi 117000, China
    6. Chronic Non-communicable Disease Prevention and Control Section, Chaoyang Center for Disease Control and Prevention, Chaoyang 122000, China
    7. Chronic Non-communicable Disease Prevention and Control Section, Liaoyang Center for Disease Control and Prevention, Liaoyang 111000, China
    8. Chronic Non-communicable Disease Prevention and Control Section, Dandong Center for Disease Control and Prevention, Dandong 118000, China
    9. Chronic Non-communicable Disease Prevention and Control Section, Benxi Center for Disease Controland Prevention, Benxi 117000, China
  • Received:2021-11-20 Revised:2022-03-15 Published:2022-06-20 Online:2022-04-21
  • Contact: Liying XING, Zuosen YANG
  • About author:
    JIAO Y K, JING L, TIAN Y M, et al. Recurrence status and combined risk factors of surviving stroke patients aged over 40 in urban areas[J]. Chinese General Practice, 2022, 25 (18) : 2244-2248.

摘要: 背景 脑卒中已成为我国城市居民第3位死亡原因,城市脑卒中高危人群中高血压、糖尿病、脂代谢异常等危险因素合并率较高。辽宁省是我国脑卒中高发地区,目前对北方城市地区的脑卒中患者复发情况及其合并危险因素的研究较少。 目的 了解辽宁省城市地区≥40岁存活脑卒中患者复发现状及其合并危险因素特征,为制定有效的二级预防策略提供理论依据。 方法 2018年9月至2020年12月,根据经济和地区分布情况,采用随机、整群、分层的抽样方法,对辽宁省辽阳市、丹东市、本溪市和朝阳市的6 349例≥40岁常住居民进行调查,本研究共纳入其中488例存活脑卒中患者为研究对象。分析存活脑卒中患者复发率及其合并危险因素。 结果 488例存活脑卒中患者中,男244例、女244例;平均年龄(65.8±7.5)岁,以60~69岁患者为主(43.7%);初发脑卒中患者352例(72.1%),复发脑卒中患者136例(27.9%),存活脑卒中患者复发率为27.9%。男、女性存活脑卒中患者复发率分别为29.5%(72例)和26.2%(64例)。不同性别存活脑卒中患者复发率比较,差异无统计学意义(χ2=0.652,P=0.419)。40~49岁、50~59岁、60~69岁、70~79岁和≥80岁存活脑卒中患者复发率分别为4/11、23.4%(22/94)、25.4%(54/213)、35.9%(47/131)和23.1%(9/39),不同年龄段男、女性存活脑卒中患者复发率比较,差异无统计学意义(P>0.05)。脑卒中复发患者现饮酒率低于脑卒中初发患者,高血压知晓率、血脂异常知晓率、血脂异常治疗率和血脂异常控制率均高于脑卒中初发患者(P<0.05)。 结论 辽宁省城市地区≥40岁存活脑卒中患者复发率较高,复发患者吸烟、缺乏运动及超重或肥胖率较高,合并高血压、糖尿病等危险因素且控制不佳,亟待针对性开展综合有效的二级预防措施以降低脑卒中患者再次复发、残障和死亡风险。

关键词: 卒中, 复发, 流行病学因素, 危险因素, 血脂异常, 高血压

Abstract:

Background

Stroke has become the 3rd leading cause of death among urban residents in China, and the combined rate ofrisk factorssuch as hypertension, diabetes, and dyslipidemia is high among urban high-risk groups. Liaoning Province is a high incidence area of stroke in China, however, there are a few studies on the recurrence of stroke and its combined risk factors in the northern urban areas.

Objective

To explore the recurrence status of surviving stroke patients aged over 40 and its combined risk factors in urban areas of Liaoning Province, in orderto provide a theoretical basis for formulating effective secondary prevention strategies.

Methods

From September 2018 to December 2020, 6 349 permanent urban residents aged over 40 in Liaoyang, Dandong, Benxi, and Chaoyang Cities of Liaoning Province were selected according to the economic and regional distribution using stratified cluster random samplingand investigated. A total of 488 surviving stroke patients were included and their recurrence rate and associated risk factors were analyzed in this study.

Results

There were 244 males and 244 females among the 488 surviving stroke patients, the average age was (65.8±7.5) years old and the proportion of patients aged 60-69 was the largest (43.7%) ; There were 352 (72.1%) first-onset stroke patients, 136 (27.9%) recurrent stroke patients, and a recurrence rate of 27.9% among surviving stroke patients; The recurrence rates of male and female surviving stroke patients were 29.5% (72 cases) and 26.2% (64 cases) , respectively, and the difference was not statistically significant (χ2=0.652, P=0.419) . The recurrence rate of stroke among people aged 40-49, 50-59, 60-69, 70-79 and ≥80 years old was 4/11, 23.4% (22/94) , 25.4% (54/213) , 35.9% (47/131) and 23.1% (9/39) , respectively, there was no significant difference in recurrence rate between male and female surviving stroke patients in different age groups (P>0.05) .The current drinking rate of the relapsed patients was lower than that of the first-onset stroke patients, and the awareness rate of hypertension, dyslipidemia, the treatment rate of dyslipidemia, and the control rate of dyslipidemia were higher than those of the first-onset stroke patients, and the difference was statistically significant (P<0.05) .

Conclusion

The recurrence rate of surviving stroke patients aged over 40 in urban areas of Liaoning Province is high, and patients with recurrence have higher rates of smoking, physical inactivity, overweight or obesity, and poor control of combined risk factors such as hypertension and diabetes mellitus, which require comprehensive and effective secondary prevention measures to reduce the risk of recurrence, disability and death in stroke patients.

Key words: Stroke, Recurrence, Epidemiologic factors, Risk factors, Dyslipidemias, Hypertension