中国全科医学 ›› 2022, Vol. 25 ›› Issue (08): 990-994.DOI: 10.12114/j.issn.1007-9572.2021.01.606

所属专题: 肿瘤最新文章合集 女性健康最新文章合集

• 流行病学研究 • 上一篇    下一篇

2005—2016年中国女性卵巢癌发病及死亡趋势研究

黄海涛1, 陈姝玉2, 耿旭3, 万晓1, 贾瑞英1, 梁丹丹1, 陈超然1,*   

  1. 1.475004 河南省开封市,河南大学护理与健康研究所
    2.475000 河南省信阳市,信阳航空职业学院航空工程学院
    3.475004 河南省开封市,河南大学医学院
  • 收稿日期:2021-11-01 修回日期:2021-12-14 出版日期:2022-03-15 发布日期:2022-03-02
  • 通讯作者: 陈超然
  • 基金资助:
    河南省社科规划决策咨询项目(2018JC38);河南大学研究生教育创新与质量提升计划项目(SYL19060141);河南省研究生教育改革与质量提升工程项目(YJS2021AL074)

Ovarian Cancer in ChinaTrends in Incidence and Mortality20052016

HUANG Haitao1CHEN Shuyu2GENG Xu3WAN Xiao1JIA Ruiying1LIANG Dandan1CHEN Chaoran1*   

  1. 1.School of Nursing and HealthHenan UniversityKaifeng 475004China

    2.School of Aviation EngineeringXinyang Aviation Vocational CollegeXinyang 475000China

    3.Henan Medical SchoolHenan UniversityKaifeng 475004China

    *Corresponding authorCHEN ChaoranProfessorE-mailkfccr@126.com

  • Received:2021-11-01 Revised:2021-12-14 Published:2022-03-15 Online:2022-03-02

摘要: 背景卵巢癌对女性健康的危害已得到全世界的广泛关注,但目前缺乏针对我国卵巢癌发病及死亡趋势分析的研究。目的通过收集《中国肿瘤登记年报》中2005—2016年卵巢癌发病与死亡数据,描述和分析该时期我国女性卵巢癌发病与死亡变化趋势,为我国卵巢癌的科学防控提供参考依据。方法整理2005—2016年卵巢癌发病与死亡数据,计算每年的标化发病率、标化死亡率、年龄别发病率和年龄别死亡率。运用Joinpoint软件计算年度变化百分比(APC)和平均年度变化百分比(AAPC),分析我国卵巢癌发病与死亡随时间(年度)的变化趋势。结果2005—2016年我国卵巢癌发病率整体呈快速上升趋势(AAPC=7.25%,P<0.05),历年城市的卵巢癌标化发病率均高于农村,35~岁年龄组以后发病率随年龄增长呈上升趋势,发病高峰主要集中出现在55~岁年龄组。2005—2016年我国卵巢癌死亡率整体呈快速上升趋势(AAPC=6.06%,P<0.05),历年城市卵巢癌标化死亡率均高于农村,35~岁年龄组以后死亡率随年龄的增长快速上升,75~岁年龄组以后死亡率逐渐下降。结论2005—2016年我国卵巢癌发病率和死亡率呈快速上升趋势,但在年龄和城乡之间表现出一定差异,应采取针对性措施,积极制订卵巢癌防治策略,降低卵巢癌的危害。

关键词: 卵巢肿瘤, 发病率, 死亡率, 流行病学研究特征, Joinpoint回归分析

Abstract: Background

The health impairment caused by ovarian cancer in female population has become a global focus. However, there is a lack of research on ovarian cancer incidence and mortality trends in Chinese female population.

Objective

To describe the trends of ovarian cancer incidence and mortality in China from 2005 to 2016 by analyzing the incidence and death data of ovarian cancer collected from Chinese Cancer Registry Annual Report, providing a basis for the scientific prevention and control of ovarian cancer in China.

Methods

The incidence and mortality of ovarian cancer in China during 2005 to 2016 were collected and input into Excel spreadsheets, then the annual age-standardized incidence rate, age-standardized mortality rate, age-specific incidence rate and age-specific mortality rate were computed. Joinpoint Regression Program was used to estimate the annual percentage change (APC) , and average annual percentage change (AAPC) to analyze the temporal trends of annual ovarian cancer incidence and mortality rates.

Results

The incidence rate of ovarian cancer showed a trend of rapid increase over the period of 2005 to 2016 (AAPC=7.25%, P<0.05) . The annual age-standardized ovarian cancer incidence rate in urban areas was higher than that in rural areas in each year. The ovarian cancer incidence rate increased obviously with age in women over the age of 35, and peaked in those aged 55 years old. From 2005 to 2016, the overall ovarian cancer mortality rate showed a rapid upward trend (AAPC=6.06%, P<0.05) . The age-standardized ovarian cancer mortality rate in urban areas was higher than that in rural areas. The mortality rate increased rapidly with age in women over 35 years of age, but decreased gradually in those aged over 75 years.

Conclusion

Both ovarian cancer incidence and mortality rates during 2005 to 2016 in China increased rapidly, but with age-specific and urban-rural differences. Therefore, targeted interventions should be taken, and strategies for ovarian cancer prevention and treatment should be developed to reduce the risk of ovarian cancer.

Key words: Ovarian Neoplasms, Incidence, Mortality, Epidemiologic study characteristics, Joinpoint regression analysis

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