关键词: 库欣综合征, 肾上腺皮质腺瘤, 全科医生, 诊断和治疗, 反思

Abstract: Cushing syndrome （CS） is a condition that is most often caused by abnormally high levels of glucocorticoid secreted by adrenal glands due to various etiologies，which can affect every system of the body，and cause a variety of complications，seriously affecting the quality of life and life span.However，due to complex and various clinical manifestations，CS is prone to missed diagnosis and misdiagnosis.We reported a case of CS caused by adrenocortical adenoma，in which the diagnostic and therapeutic process was detailed，in particular，the reasons for delayed diagnosis were analyzed thoroughly，such as lack of adequate understanding of multiple symptoms of CS，and vigilance for secondary hypertension as well as a comprehensive assessment of the patient's age，sex and physique，and paying insufficient attention to the diagnostic role of routine blood test in CS.Then we proposed that primary care physicians should make efforts to recognize diseases with diverse clinical manifestations，and improve techniques for consultations and comprehensive examinations based on a patient-centered approach to enhance the possibility of making an early diagnosis.Moreover，a series of policy recommendations were put forward to improve the quality of primary health services so that patients with complex symptoms can be diagnosed and treated as soon as possible.

Key words: Cushing syndrome, Adrenocortical adenoma, General practitioner, Diagnostic and therapeutic, Reflection