中国全科医学 ›› 2020, Vol. 23 ›› Issue (22): 2804-2808.DOI: 10.12114/j.issn.1007-9572.2020.00.176

所属专题: 睡眠问题专题研究

• 专题研究 • 上一篇    下一篇

睡眠质量与老年肌肉减少症关系的研究

姚雪梅,李美艳,吴栋,肖辉*   

  1. 830011新疆维吾尔自治区乌鲁木齐市,新疆医科大学公共卫生学院
    *通信作者:肖辉,教授,博士生导师;E-mail:xh20108262@sina.com
  • 出版日期:2020-08-05 发布日期:2020-08-05
  • 基金资助:
    新疆维吾尔自治区自然科学基金资助项目(2016D01C187);新疆维吾尔自治区“十三五”重点学科(高原学科)——公共卫生与预防医学

The Relationship between Sleep Quality and Sarcopenia in the Elderly

YAO Xuemei,LI Meiyan,WU Dong,XIAO Hui*   

  1. School of Public Health,Xinjiang Medical University,Urumqi 830011,China
    *Corresponding author:XIAO Hui,Professor,Doctoral supervisor;E-mail:xh20108262@sina.com
  • Published:2020-08-05 Online:2020-08-05

摘要: 背景 肌肉减少症与睡眠障碍均在老年人群中高发。睡眠质量差可抑制干扰合成代谢激素,从而影响骨骼肌合成,但关于睡眠质量与老年肌肉减少症之间关系的研究较少。目的 探讨睡眠质量与老年肌肉减少症之间的关系,为老年肌肉减少症的防治提供科学依据。方法 采用随机抽样的方法,对2017年12月—2018年12月前来乌鲁木齐市某体检中心体检的1 391例≥60岁老年人进行问卷调查(一般人口学资料及睡眠质量)和体格检查(四肢骨骼肌质量、步速、握力)。睡眠质量的调查采用匹兹堡睡眠质量指数量表(PSQI),肌肉减少症诊断参照肌肉减少症亚洲工作组诊断标准。睡眠质量对老年肌肉减少症的影响采用多因素Logistic回归进行分析。结果 1 391例被调查对象中,194例(13.9%)患有肌肉减少症;PSQI平均得分为(6.22±3.87)分,713例(51.3%)PSQI>5分,即睡眠质量较差。不同年龄、月收入、婚姻状况、饮酒情况老年人肌肉减少症发生情况比较,差异有统计学意义(P<0.05)。不同性别、年龄、文化程度、月收入、婚姻状况、吸烟情况、饮酒情况患者睡眠质量较差者占比比较,差异有统计学意义(P<0.05)。肌肉减少症患者PSQI总分、主观睡眠质量、入睡时间、睡眠时间、睡眠效率及日间功能障碍得分高于非肌肉减少症者,差异有统计学意义(P<0.05)。与PSQI≤5分相比,PSQI>5分患肌肉减少症的风险较大〔OR(95%CI)=1.74(1.27,2.38)〕。按性别分层后,与PSQI≤5分相比,女性PSQI>5分患肌肉减少症的风险较大〔OR(95%CI)=2.17(1.37,3.43)〕,男性PSQI>5分与PSQI≤5分者患肌肉减少症的风险差异无统计学意义〔OR(95%CI)=1.51(0.96,2.37)〕。结论 对于≥60老年女性而言,睡眠质量差是肌肉减少症的危险因素。

关键词: 老年人, 睡眠质量, 肌肉减少症

Abstract: Background Both sarcopenia and sleep disorders have high incidence in the elderly. Poor sleep quality can inhibit anabolic hormones,which affects the synthesis of skeletal muscle. However,there is little research on the relationship between sleep quality and sarcopenia in the elderly. Objective To explore the relationship between sleep quality and sarcopenia in the elderly,and provide scientific basis for the prevention and treatment of senile sarcopenia. Methods Using the method of random sampling,a questionnaire survey(about general demographic data and sleep quality) and physical examination(including skeletal muscle mass of limbs,walking speed,and grip strength) were conducted in 1 391 elderly people aged 60 and older who came to a physical examination center in Urumqi from December 2017 to December 2018. The sleep quality was estimated by The Pittsburgh Sleep Quality Index(PSQI). The sarcopenia was diagnosed by the criteria of Asian Working Group for Sarcopenia. The effect of sleep quality on sarcopenia was analyzed by multivariate logistic regression. Results Of the 1 391 respondents,194(13.9%) had sarcopenia,and the mean PSQI score was(6.22±3.87). And 713(51.3%) respondents had a PSQI score>5,which meant their sleep quality was poor. There were significant differences in the incidence of sarcopenia among the elderly with different ages,monthly income,marital status and drinking status(P<0.05). The proportions of poor sleep quality in patients with different genders,ages,education levels,monthly income,marital status,smoking ststus and drinking status were statistically significant(P<0.05). Patients with sarcopenia had significantly higher PSQI scores and scores of subjective sleep quality,time to sleep,sleep time,sleep efficiency and daytime dysfunction than those without sarcopenia(P<0.05). Compared with patients with PSQI scores≤5,those with PSQI scores>5 had a higher risk of sarcopenia〔OR(95%CI)=1.74(1.27,2.38)〕.After stratified by gender,compared with patients with PSQI scores≤5,female patients with PSQI scores>5 had a higher risk of sarcopenia〔OR(95%CI)=2.17(1.37,3.43)〕,while no significant difference was found in male patients〔OR(95%CI)=1.51(0.96,2.37)〕. Conclusion Poor sleep quality is a risk factor of sarcopenia in women over 60.

Key words: Aged, Sleep quality, Sarcopenia