Page 125 - 中国全科医学2022-29
P. 125

·3706· http://www.chinagp.net   E-mail:zgqkyx@chinagp.net.cn


                                                               [9]DOMÍNGUEZ-SANCHÉZ M A,BUSTOS-CRUZ R H,VELASCO-
                                                                   ORJUELA G P,et al. Acute effects of high intensity,resistance,
                                                                   or combined protocol on the increase of level of neurotrophic factors in
                                                                   physically inactive overweight adults:the BrainFit study[J]. Front
                                                                   Physiol,2018,9:741. DOI:10.3389/fphys.2018.00741.
                                                               [10]KONOPKA A R,ASANTE A,LANZA I R,et al. Defects in
                                                                    mitochondrial efficiency and H 2 O 2  emissions in obese women are
                                                                    restored to a lean phenotype with aerobic exercise training[J].
              注:High-intensity interval training= 高 强 度 间 歇 训 练,    Diabetes,2015,64(6):2104-2115. DOI:10.2337/db14-
           Mitochondrial biogenesis= 线 粒 体 生 物 发 生,PGC-1α= 过 氧 化 物 酶
                                                                    1701.
           体增殖物激活受体 γ 共激活因子 1α,TFAM= 线粒体转录因子,
                                                               [11]LAHERA V,DE LAS HERAS N,LÓPEZ-FARRÉ A,et al. Role
           mtDNA= 线粒体 DNA,Mitochondrial dysfunction= 线粒体功能障碍,
                                                                    of mitochondrial dysfunction in hypertension and obesity[J]. Curr
           Cognitive function= 认知功能
                                                                    Hypertens Rep,2017,19(2):11. DOI:10.1007/s11906-
                     图 2 HIIT 促进认知功能的线粒体机制
           Figure 2 The possible mechanisms of high-intensity interval training on   017-0710-9.
           improving obesity-related cognitive impairment      [12]DE  MELLO  A  H,COSTA  A  B,ENGEL  J  D  G,et  al.
                                                                    Mitochondrial dysfunction in obesity[J]. Life Sci,2018,192:
           功能损伤的保护作用。                                               26-32. DOI:10.1016/j.lfs.2017.11.019.
               作者贡献:蔡明负责文献和资料收集、论文撰写及论文                        [13]CUNARRO J,CASADO S,LUGILDE J,et al. Hypothalamic
           图片制作;王晓军负责文章的质量控制及审校;陈晓艳负责                               mitochondrial dysfunction as a target in obesity and metabolic
                                                                    disease[J]. Front Endocrinol (Lausanne),2018,9:283.
           文章的文献 / 资料整理;胡静芸负责研究命题的提出、设计及
                                                                    DOI:10.3389/fendo.2018.00283.
           负责最终版本修订,对论文负责。所有作者确认论文终稿。
                                                               [14]MARKHAM  A,BAINS  R,FRANKLIN  P,et  al.  Changes
               本文无利益冲突。
                                                                    in  mitochondrial  function  are  pivotal  in  neurodegenerative
           参考文献
                                                                    and  psychiatric  disorders:how  important  is  BDNF?[J].
           [1]国家国民体质监测中心 . 第五次国民体质监测公报[EB/OL].
                                                                    Br  J  Pharmacol,2014,171(8):2206-2229.  DOI:
               (2021-12-30)[2022-01-22]. https://www.ciss.cn/tzgg/
                                                                    10.1111/bph.12531.
               info/2021/32030.html.
                                                               [15]WANG D M,YAN J Q,CHEN J,et al. Naringin improves
           [2]World Obesity Federation Global Obesity Observatory. Scorecards -
                                                                    neuronal insulin signaling,brain mitochondrial function,and
               Obesity:missing the 2025 targets[EB/OL]. [2022-01-22].
                                                                    cognitive function in high-fat diet-induced obese mice[J].
               https://data.worldobesity.org/publications/?cat=2#CN.
                                                                    Cell  Mol  Neurobiol,2015,35(7):1061-1071.  DOI:
           [3]LIN J D,WU P H,TARR P T,et al. Defects in adaptive energy
                                                                    10.1007/s10571-015-0201-y.
               metabolism with CNS-linked hyperactivity in PGC-1alpha null
                                                               [16]SA-NGUANMOO P,TANAJAK P,KERDPHOO S,et al. FGF21
               mice[J]. Cell,2004,119(1):121-135. DOI:10.1016/j.
                                                                    improves cognition by restored synaptic plasticity,dendritic spine
               cell.2004.09.013.
                                                                    density,brain mitochondrial function and cell apoptosis in obese-
           [4]DYE L,BOYLE N B,CHAMP C,et al. The relationship between
                                                                    insulin resistant male rats[J]. Horm Behav,2016,85:86-95.
               obesity and cognitive health and decline[J]. Proc Nutr Soc,
                                                                    DOI:10.1016/j.yhbeh.2016.08.006.
               2017,76(4):443-454. DOI:10.1017/S0029665117002014.
                                                               [17]HO  L,VARGHESE  M ,WANG  J,e t  al .  Di eta ry
           [5]CRISPINO M,TRINCHESE G,PENNA E,et al. Interplay between   supplementation with decaffeinated green coffee improves diet-
               peripheral and central inflammation in obesity-promoted disorders:  induced insulin resistance and brain energy metabolism in
               the impact on synaptic mitochondrial functions[J]. Int J Mol Sci,  mice[J]. Nutr Neurosci,2012,15(1):37-45. DOI:
               2020,21(17):E5964. DOI:10.3390/ijms21175964.         10.1179/1476830511Y.0000000027.
           [6]SRIPETCHWANDEE J,CHATTIPAKORN N,CHATTIPAKORN     [18]PATTI M E,CORVERA S. The role of mitochondria in the
               S C. Links between obesity-induced brain insulin resistance,brain   pathogenesis of type 2 diabetes[J]. Endocr Rev,2010,31(3):
               mitochondrial dysfunction,and dementia[J]. Front Endocrinol   364-395. DOI:10.1210/er.2009-0027.
               (Lausanne),2018,9:496. DOI:10.3389/fendo.2018.00496.  [19]YAMASHIMA T,OTA T,MIZUKOSHI E,et al. Intake of ω-6
           [7]CAI Q,TAMMINENI P. Alterations in mitochondrial quality control   polyunsaturated fatty acid-rich vegetable oils and risk of lifestyle
               in Alzheimer's disease[J]. Front Cell Neurosci,2016,10:24.   diseases[J]. Adv Nutr,2020,11(6):1489-1509. DOI:
               DOI:10.3389/fncel.2016.00024.                        10.1093/advances/nmaa072.
           [8]RODRIGUEZ A L,WHITEHURST M,FICO B G,et al. Acute   [20]LEE  S,KIM  J  Y,KIM  E,et  al.  Assessment  of  cognitive
               high-intensity interval exercise induces greater levels of serum   impairment in a mouse model of high-fat diet-induced metabolic
               brain-derived neurotrophic factor in obese individuals[J]. Exp   stress with touchscreen-based automated battery system[J].
               Biol Med (Maywood),2018,243(14):1153-1160. DOI:      Exp  Neurobiol,2018,27(4):277-286.  DOI:
               10.1177/1535370218812191.                            10.5607/en.2018.27.4.277.
   120   121   122   123   124   125   126   127   128   129   130