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cardiovascular and cerebrovascular diseases in this population. There is little consistency between studies on dyslipidemia prevalence
in Chinese older adults due to differences of size and features of sample，design and setting. Objective To systematically evaluate
the prevalence of dyslipidemia among Chinese older adults. Methods Cross-sectional studies relevant to the prevalence of
dyslipidemia among Chinese elderly population were searched in databases including CNKI，CBM，CQVIP，WanFang，PubMed，
Web of Science，Embase and the Cochrane Library from inception to May 2021. Two researchers performed literature screening and
data extraction，separately. The Agency for Healthcare Research and Quality methodology checklist was used to assess the risk of
bias. Stata 15.1 was adopted for meta-analysis. Results A total of 19 cross-sectional studies were included，involving 101 931
cases，and 45 785 of them had dyslipidemia. Meta-analysis results showed that the overall prevalence of dyslipidemia among the
participants was 48.0%〔95%CI（41.0%，54.0%）〕. Specifically，the prevalence of elevated total cholesterol（TC），triglyceride（TG），
and low-density lipoprotein cholesterol（LDL-C）as well as lowered low high-density lipoprotein cholesterol（HDL-C）was 19.7%
〔95%CI（13.8%，25.5%）〕，20.8%〔95%CI（16.2%，25.4%）〕，15.3%〔95%CI（10.7%，19.8%）〕，and 20.2%
〔95%CI（7.9%，32.4%）〕，respectively. Sex-specific analysis found that men had higher prevalence of elevated LDL-C than
women（17.2% vs 9.0%）. Women had higher overall prevalence of dyslipidemia than men（48.8% vs 39.5%）. Moreover，women
also had higher prevalence of elevated TC（24.0% vs 12.9%），and TG（23.4% vs 19.0%），as well as lowered HDL-C（20.4%
vs 14.7%）. Age-specific analysis revealed that dyslipidemia prevalence in age groups of 60-69，70-79，and ≥ 80 years old was
39.9%，31.8%，and 31.4%，respectively，showing a trend of decrease with age. The prevalence of elevated TC in 60-69 year-
olds（12.9%）was higher than that of 70-79 year-olds（12.1%）or 80 year-olds and above（9.5%）. The prevalence of elevated
LDL-C in 60-69 year-olds（10.0%）was higher than that of 70-79 year-olds（9.4%）or 80 year-olds and above（6.5%）. The
prevalence of elevated TG in 70-79 year-olds（19.3%）was higher than that of 60-69 year-olds（16.4%）or 80 year-olds and
above（15.5%）. The prevalence of lowered HDL-C in 70-79 year-olds（10.5%）was higher than that of 60-69 year-olds（9.7%）
or 80 year-olds and above（9.5%）. Those aged ≥ 80 years had lower prevalence of various forms of dyslipidemia than 60-69 year-
olds and 70-79 year-olds. Region-specific analysis indicated that compared to those from western China，participants from eastern
China had higher overall prevalence of dyslipidemia（49.3% vs 36.8%）. Moreover，they also showed higher prevalence of elevated
TC（23.0% vs 11.4%），elevated LDL-C（21.3% vs 7.8%）and lowered HDL-C（13.5% vs 7.8%）. However，they had slightly
lower prevalence of elevated TG（19.7% vs 20.0%）. Conclusion The overall prevalence of dyslipidemia was high in Chinese older
adults. Sex-，age group- and region-specific differences were found in the overall prevalence of dyslipidemia，and prevalence of
various forms of dyslipidemia. Due to limited number and non-ideal quality of the included studies，the above conclusions need to be
verified by more high-quality studies.
【Key words】 Dyslipidemia；Aged；Prevalence；Cross-sectional studies；Meta-analysis

国家统计局近期发布的数据显示，截至 2019 年底，中 1 资料与方法
国≥ 60 岁老年人口已达 2.53 亿，占总人口的 18.1% ［1］ 。 1.1 纳入与排除标准 纳入标准：（1）研究类型为横断面
2021—2050 年是加速老龄化阶段。到 2050 年，中国≥ 60 岁 研究；（2）研究对象为中国≥ 60 岁老年人群；（3）结局指
老年人口将达 4 亿，占总人口 30% 以上 ［2］ 。人口老龄化是社 标为血脂异常患病率，包括血脂异常总体患病率、高胆固醇
会发展的重要趋势，也是今后较长一段时期内中国的基本国 （TC）血症患病率、高三酰甘油（TG）血症患病率、高低密
情 ［2］ 。老年人随着年龄的增长，体内各脏器的生理功能逐渐 度脂蛋白胆固醇（LDL-C）血症患病率、低高密度脂蛋白胆
下降，罹患疾病的风险也随之增加。近年来，中国老年人血 固醇（HDL-C）血症患病率。排除标准：（1）以住院或门诊
脂异常的患病率较前明显上升。血脂异常是冠状动脉粥样硬 患者作为研究对象的文献；（2）未明确报告血脂异常诊断标
化性心脏病、心肌梗死、缺血性脑卒中等心脑血管疾病的重 准或依据的文献；（3）研究数据有误或无法完整提取的文献；
要危险因素 ［3］ 。因此，了解中国老年人血脂异常流行情况， （4）重复发表的文献；（5）综述、评论或会议记录；（6）
并积极采取健康管理措施控制血脂异常，对于促进中国老年 非中、英文文献。
人健康老化具有重要意义 ［4-5］ 。目前，针对中国老年人血脂 1.2 文献检索策略 于 2021 年 5 月，计算机检索中国知网、
异常的多中心、大样本流行病学调查较少，虽然有研究者对 中国生物医学文献数据库、维普中文科技期刊全文数据库、
中国老年人血脂异常的患病情况进行了探讨，但受样本量、 万方数据知识服务平台、PubMed、Web of Science、EmBase、
研究设计方案、调查地域、调查对象群体特征等因素的影响， The Cochrane Library，检索有关中国老年人血脂异常的横断
调查结果也存在着较大差异。基于此，本研究采用 Meta 分 面研究，检索时限均为建库至 2021 年 5 月。此外，检索纳入
析对中国老年人血脂异常患病率进行系统评价，旨在为血脂 文献的参考文献，以补充获取相关文献。检索策略采用主题
异常及心脑血管疾病的早期防治及卫生政策的制定提供科学 词与自由词相结合的方式。英文检索词包括：dyslipidemia、
依据。 dyslipoproteinemia、blood lipids、blood fat、serum lipids、