Abstract: Background　With the acceleration of population aging，an increasing chronic disease prevalence is seen in middle-aged and elderly Chinese people，and a widespread prevalence of multiple chronic conditions is found in this population，which have brought unprecedented challenges to the management of chronic diseases. Objective　To systematically evaluate the prevalence rate of multiple chronic conditions in middle-aged and elderly population （≥45 years old） from 2010 to 2019 in China，providing a basis for the prevention of multiple chronic conditions. Methods　We searched cross-sectional studies regarding multiple chronic conditions prevalence in middle-aged and elderly Chinese people published from 2010-01-01 to 2020-01-01 in Chinese from databases of CNKI，Wanfang Data and VIP，and those in English from databases of the Cochrane Library，PubMed，Web of Science，and so on. Data extraction and quality evaluation of the included studies were performed. Stata 14.0 was used for statistical analysis. Results　A total of 25 studies were included，with a total of 173 085 patients. Meta analysis showed that the prevalence rate of multiple chronic conditions in middle-aged and elderly Chinese people was 41%〔95%CI（35%，46%）〕. Subgroup analysis showed that the prevalence of multiple chronic conditions was 41% in women〔95%CI（33%，50%）〕 and 38% in men〔95%CI（31%，45%）〕. The prevalence of 2 and 3 chronic diseases was 23%〔95%CI（20%，26%）〕，and 11%〔95%CI（9%，14%）〕，respectively. The prevalence of multiple chronic conditions was 41%〔95%CI（34%，47%）〕 from 2010 to 2015，and was 43%〔95%CI（28%，58%）〕 from 2016 to January 1，2020. The prevalence of multiple chronic conditions was 41%〔95%CI（34%，49%）〕 and 38%〔95%CI （27%，49%）〕 in those living in southern and northern China，respectively. Conclusion　The prevalence of multiple chronic conditions in this population is relatively high. Therefore，relevant departments should pay attention to early screening of chronic conditions in high-risk groups and provide targeted preventive measures for them.

Key words: Health services for the aged, Chronic disease, Multimorbidity, Prevalence, China, Meta analysis

摘要： 背景　我国人口老龄化问题的日益加剧，在一定程度上加快了中老年人慢性病患病率的进程。随着慢性病的日益流行，慢性病共病为慢性病的管理带来了前所未有的挑战。慢性病共病在我国中老年人群中普遍存在。目的　系统评价2010—2019年我国中老年人群（≥45岁）慢性病共病的患病率，为慢性病共病的预防提供依据。方法　计算机检索中国期刊全文数据库、万方数据知识服务平台和维普数据库等中文数据库，以及Cochrane Library、PubMed和Web of Science等英文数据库中有关我国中老年人慢性病共病患病率的横断面研究，检索2010-01-01至2020-01-01月公开发表的文章，并对纳入的研究进行质量评价与数据提取，采用Stata 14.0软件进行统计学分析。结果　共纳入25篇横断面研究，涉及173 085例患者。Meta分析结果显示，我国中老年人慢性病共病患病率为41%〔95%CI（35%，46%）〕。亚组分析结果显示，女性慢性病共病患病率为41%〔95%CI（33%，50%）〕，男性慢性病共病患病率为38%〔95%CI（31%，45%）〕；共病2种慢性病的患病率为23%〔95%CI（20%，26%）〕，共病3种慢性病的患病率为11%〔95%CI（9%，14%）〕；2016—2019年慢性病共病患病率为43%〔95%CI（28%，58%）〕，2010—2015年慢性病共病患病率为41%〔95%CI（34%，47%）〕；南方慢性病共病患病率为41%〔95%CI（34%，49%）〕，北方慢性病共病患病率为38%〔95%CI（27%，49%）〕。结论　我国中老年人慢性病共病患病率较高。因此，相关部门应重视对高危人群的早期筛查，并有针对性地采取预防措施。

关键词: 老年人保健服务, 慢性病, 共病现象, 患病率, 中国, Meta分析