Abstract: Objective　To investigate the relationships of overweight/obesity，exercise，and their interaction with phlegm-dampness constitution in normal adults.Methods　The physical examination data of the Beijing part during March 2015 to May 2016 were collected from the Systematic Survey of TCM Pulse Diagnosis Physiological Parameters in Normal Adult Populations with Different Constitutions Database.In Beijing，after excluding those with missing variables and very low body weight（BMI<18.5 kg/m2），970 eligible individuals were included.Of them，262 cases（27.0%） with the highest scores of Phlegm Dampness Constitution Subscale（PDCS），a subscale of the TCM Physical Constitution Scale，and 262 cases（27.0%） with the lowest scores of PDCS were assigned to high score group and low score group，respectively.Logistic regression analysis was used to analyze the impacts of overweight/obesity，exercise and their interaction on phlegm-dampness constitution after adjusting for the confounding factors of gender，age，education level，smoking preference and drinking preference.Results　Multivariate Logistic regression analysis showed that both overweight〔OR=1.981，95%CI（1.275，3.079），P<0.05〕and obesity〔OR=4.032，95%CI（1.985，8.190），P<0.05〕 increased the risk of having higher scores of PDCS，but exercise habits had no effect on the scores of PDCS（P>0.05）.When considered overweight/obesity and exercise habits as stratified factors，Logistic regression analysis demonstrated that individuals without overweight/obesity and exercise habits〔OR=2.735，95%CI（1.644，4.551），P<0.05〕and those with overweight/obesity but without exercise habits〔OR=2.154，95%CI（1.168，3.976），P<0.05〕had higher risk of having higher scores of PDCS than those with exercise habits but without overweight/obesity.Multiplicative and additive interaction analyses showed that there were no obvious interactions between overweight/obesity and exercise.Conclusion　Overweight/obesity and lack of exercise increase the possibility of having phlegm-dampness constitution，although there is no obvious interaction between the two.Exercise and weight management help to improve phlegm-dampness constitution.

Key words: Overweight, Obesity, Exercise, Phlegm-damp constitution, Root cause analysis, Interaction

摘要： 目的　探讨超重/肥胖、运动及其交互作用对痰湿体质的影响。方法　在“正常人群中不同体质中医脉诊生理参数系统调查”数据库中，选取2015年3月—2016年5月在北京市获得的健康体检数据，排除相关变量缺失、体质量过低（BMI<18.5 kg/m2）者，将符合条件的970例受试者的中医体质量表中痰湿体质亚量表得分由高到低排序，以得分的前262例（27.0%）为高分组、后262例（27.0%）为低分组。采用Logistic回归分析，将性别、年龄、文化程度、吸烟偏好、饮酒偏好作为混杂因素，探讨超重/肥胖、运动及其交互作用对痰湿体质的影响。结果　多因素Logistic回归分析显示，超重、肥胖会增加高痰湿体质得分的风险〔OR（95%CI）分别为1.981（1.275，3.079）、4.032（1.985，8.190），P<0.05〕；运动习惯对痰湿体质无影响（P>0.05）。按是否超重/肥胖、有无运动习惯分层后的Logistic回归分析显示，非超重/肥胖+无运动习惯者、超重/肥胖+无运动习惯者的高痰湿体质得分风险高于非超重/肥胖+有运动习惯者〔OR（95%CI）分别为2.735（1.644，4.551）、2.154（1.168，3.976），P<0.05〕。相乘和相加交互作用分析均显示，超重/肥胖、运动对痰湿体质的影响不存在交互作用。结论　超重/肥胖、缺乏运动会增加痰湿体质的倾向，但二者间在统计学上无交互作用，进行运动和体质量管理将有助于调护痰湿体质。

关键词: 超重, 肥胖, 运动, 痰湿体质, 影响因素分析, 交互作用