Advances in Dietary Restriction on the Regulation of Organismal Immune Function

doi:10.12114/j.issn.1007-9572.2023.0659

Abstract

Abstract:

Nutritional status may influence the immune response, and dietary restriction (DR) , as an important dietary intervention, has been shown to potentially play an important regulatory role in the activation and effector functioning of immune cells and is involved in the progression of different diseases. Therefore, this review summarises the effects of DR on the functional status of innate immune cells, such as neutrophils and monocytes, as well as adaptive immune cells, such as B cells and T cells, and also discusses the impact of DR as a therapeutic strategy on immune function in disease states such as infections, chronic inflammation, and cancer.

Key words: Fasting, Dietary restriction, Immunomodulation, Review

摘要：

营养状况可能影响免疫反应，饮食限制作为一种重要的饮食干预手段，已被证明可能会对免疫细胞的激活和效应功能的发挥起着重要的调节作用，并且参与着不同疾病的进展，因此，本综述总结了饮食限制对中性粒细胞、单核细胞等先天免疫细胞以及B细胞、T细胞等适应性免疫细胞功能状态的影响，并且还讨论了饮食限制作为一种治疗策略，在感染、慢性炎症以及癌症等疾病状态下对免疫功能的影响。

关键词: 禁食, 饮食限制, 免疫调节, 综述

GAO Jiaxin,ZHOU Ruihan,WANG Fangfang, et al. Advances in Dietary Restriction on the Regulation of Organismal Immune Function[J]. Chinese General Practice, 2025, 28(32): 4102-4109. DOI: 10.12114/j.issn.1007-9572.2023.0659.
高佳新,周蕊寒,王芳芳等. 饮食限制对机体免疫功能调节作用的研究进展[J]. 中国全科医学, 2025, 28(32): 4102-4109. DOI: 10.12114/j.issn.1007-9572.2023.0659.

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