The percentage of older population of the total population is increasing in developed areas of developing countries, and the impact and contribution of population composition factors towards cancer mortality are still unclear.

To analyze the epidemiological characteristics and trend of cancer mortality among community-living residents in central Pudong New Area of Shanghai from 2007 to 2020.

From January to December 2021, we retrospectively collected the death data during 2007 to 2020 of registered permanent residents living in Dongming Road Community of Pudong New Area from the all-cause death monitoring database, and population composition data from Pudong New Area Public Security Bureau. We used the crude mortality rate (CMR) , standardized mortality rate (SMR, with reference to the SMR of the general Chinese population in 2010) , and average annual percent change (AAPC) to analyze the status and trends of cancer mortality, and used the decomposition method to estimate the contribution rates of demographic and non-demographic factors to the change of cancer mortality.

From 2007 to 2020, a total of 2 446 cancer-induced deaths were reported by the Dongming Road Community, accounting for 28.48% of the total reported deaths (8 589 cases) . The CMR of cancers was 268.56/10⁵, in which the CMR due to lung cancer, colorectal cancer, and gastric cancer was 69.61/10⁵, 33.05/10⁵ and 31.84/10⁵, respectively. The SMR of cancers was 71.46/10⁵ , in which the SMR due to lung cancer, colorectal cancer, and gastric cancer was 33.12/10⁵, 15.46/10⁵, and 15.29/10⁵, respectively. During this period, the CMR for cancers among men, women and the whole population remained stable (Z=1.82, -0.54, 0.87, P>0.05) . The CMR and SMR in men were higher than those in women (u=6.69, P<0.001; Z=-13.22, P<0.001) . The SMR in men showed a downward trend (AAPC=-1.80%, Z=-2.19, P<0.05) , while in women, it remained stable (Z=-1.63, P>0.05) . As in the whole population, it showed a downward trend year by year (AAPC=-1.73%, Z=-3.09, P=0.010) . Furthermore, the CMR for cancers in those aged 65-79 showed a downward trend gradually (AAPC=-4.17%, Z=-1.80, P<0.01) . The difference between the CMR of cancers during 2007—2013 and that during 2014—2020 was 3.80/10⁵. The added value of demographic factors to mortality was 28.97/10⁵, with a contribution rate of 53.51%. And the added value of non-demographic factors to mortality -25.17/10⁵, with a contribution rate of 46.49%.

In Dongming Road Community from 2007 to 2020, both SMRs for cancers in the whole population and male residents demonstrated a downward trend, and the CMR for cancers in those aged 65-79 demonstrated a year-by-year downward trend. Older age may be the major demographic factor contributing to the stability of CMR of cancers.

发展中国家的发达地区人口结构逐步老龄化，而人口构成因素对恶性肿瘤死亡带来的影响及贡献情况尚不清楚。

分析上海市浦东新区中部社区2007—2020年居民恶性肿瘤死亡情况，并总结其变化趋势。

2021年1—12月，回顾性收集浦东新区东明路街道社区2007—2020年户籍居民全死因监测系统库的死亡数据。人口构成资料由上海市浦东新区公安局提供。采用粗死亡率（CMR）、标化死亡率（SMR，以2010年中国标准人口为参照）、年度变化百分比（AAPC）分析当地居民恶性肿瘤死亡情况，并采用死亡率差别分解法探究人口构成因素和非人口构成因素对CMR变化的贡献率。

2007—2020年浦东新区东明路街道社区合计报告恶性肿瘤死亡2 446例，占同期全社区总死亡人数（8 589例）的28.48%，CMR为268.56/10万，SMR为71.46/10万；其中肺癌CMR为69.61/10万，SMR为33.12/10万；结直肠癌CMR为33.05/10万，SMR为15.46/10万；胃癌CMR为31.84/10万，SMR为15.29/10万。2007—2020年浦东新区东明路街道社区男性、女性、全人口恶性肿瘤CMR保持稳定（Z值分别为1.82、-0.54、0.87，P>0.05）。2007—2020年浦东新区东明路街道社区男性CMR、SMR高于女性（u=6.69，P<0.001；Z=-13.22，P<0.001）；男性恶性肿瘤SMR呈下降趋势（AAPC=-1.80%，Z=-2.19，P<0.05），女性恶性肿瘤SMR保持稳定（Z=-1.63，P>0.05），全人口恶性肿瘤SMR呈逐年下降趋势（AAPC=-1.73%，Z=-3.09，P=0.010）。2007—2020年在浦东新区东明路街道社区65~79岁居民CMR呈逐年下降趋势（AAPC=-4.17%，Z=-1.80，P<0.01）。2007—2013年与2014—2020年恶性肿瘤CMR差别为3.80/10万，人口构成因素和非人口构成因素对死亡率增加值的贡献分别为28.97/10万和-25.17/10万，贡献率分别为53.51%和46.49%。

2007—2020年浦东新区东明路街道社区男性和全人口恶性肿瘤SMR已出现下降趋势，65~79岁居民CMR呈逐年下降趋势，人口结构因素（老龄化）是恶性肿瘤CMR未见下降的主要原因。