
Chinese General Practice ›› 2022, Vol. 25 ›› Issue (18): 2188-2193.DOI: 10.12114/j.issn.1007-9572.2022.02.002
Special Issue: 男性健康最新文章合辑; 全民健康最新文章合辑; 老年问题最新文章合辑; 骨质疏松最新文章合辑; 骨健康最新文章合辑; 老年人群健康最新文章合辑
• Article·Osteoporosis Study • Previous Articles Next Articles
Received:2021-11-05
Revised:2022-01-05
Published:2022-06-20
Online:2022-01-13
Contact:
Xiuyan WANG
About author:
通讯作者:
王秀艳
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2022.02.002
| 组别 | 例数 | 年龄( | 腹围( | BMI ( | 吸烟史〔n(%)〕 | 高血压史〔n(%)〕 | 每日活动量<1 h 〔n(%)〕 | FBG ( | TG ( | TC ( |
|---|---|---|---|---|---|---|---|---|---|---|
| 骨质正常组 | 76 | 69.7±4.0 | 86.1±5.9 | 26.8±2.9 | 30(39.5) | 31(40.8) | 24(31.6) | 5.81±1.45 | 1.68±1.37 | 4.68±0.91 |
| 骨量减少组 | 123 | 68.9±3.6 | 83.1±3.4 | 25.4±3.0 | 47(38.2) | 59(48.0) | 53(43.0) | 5.99±1.65 | 1.75±0.85 | 4.70±0.83 |
| 骨质疏松组 | 51 | 69.7±3.5 | 81.0±3.8 | 22.8±3.1 | 19(37.3) | 23(45.1) | 33(64.0) | 5.88±1.29 | 1.97±1.06 | 4.97±0.75 |
| F(χ2)值 | 1.326 | 22.399 | 26.507 | 0.067a | 0.977a | 13.674a | 0.345 | 1.170 | 0.274 | |
| P值 | 0.267 | <0.001 | <0.001 | 0.967 | 0.613 | 0.001 | 0.709 | 0.312 | 0.745 | |
| 组别 | LDL-C ( | HDL-C ( | 25(OH)D3 ( | T值( | Z值( | PRGE ( | E2 ( | 睾酮( | FSH ( | LH ( |
| 骨质正常组 | 2.70±0.84 | 1.22±0.33 | 20.51±3.95 | -0.53±0.44 | 0.61±0.48 | 0.74±0.06 | 27.35±5.18 | 397.89±73.48 | 16.48±5.91 | 4.63±0.85 |
| 骨量减少组 | 2.75±0.71 | 1.46±0.38 | 17.90±5.58 | -1.64±0.32 | -0.51±0.36 | 0.76±0.14 | 24.33±2.59 | 357.45±78.86 | 15.32±6.32 | 4.69±0.87 |
| 骨质疏松组 | 2.92±0. 70 | 1.61±0.45 | 14.76±5.32 | -2.74±0.29 | -1.63±0.41 | 0.75±0.07 | 20.74±4.60 | 327.87±73.99 | 14.09±4.32 | 4.72±0.79 |
| F(χ2)值 | 1.426 | 29.587 | 19.630 | 27.630 | 25.220 | 0.719 | 42.676 | 26.635 | 1.484 | 0.217 |
| P值 | 0.242 | <0.001 | <0.001 | <0.001 | <0.001 | 0.488 | <0.001 | <0.001 | 0.229 | 0.805 |
Table 1 Comparison of baseline data and laboratory examination results in elderly men with normal bone mineral density,osteopenia and osteoporosis
| 组别 | 例数 | 年龄( | 腹围( | BMI ( | 吸烟史〔n(%)〕 | 高血压史〔n(%)〕 | 每日活动量<1 h 〔n(%)〕 | FBG ( | TG ( | TC ( |
|---|---|---|---|---|---|---|---|---|---|---|
| 骨质正常组 | 76 | 69.7±4.0 | 86.1±5.9 | 26.8±2.9 | 30(39.5) | 31(40.8) | 24(31.6) | 5.81±1.45 | 1.68±1.37 | 4.68±0.91 |
| 骨量减少组 | 123 | 68.9±3.6 | 83.1±3.4 | 25.4±3.0 | 47(38.2) | 59(48.0) | 53(43.0) | 5.99±1.65 | 1.75±0.85 | 4.70±0.83 |
| 骨质疏松组 | 51 | 69.7±3.5 | 81.0±3.8 | 22.8±3.1 | 19(37.3) | 23(45.1) | 33(64.0) | 5.88±1.29 | 1.97±1.06 | 4.97±0.75 |
| F(χ2)值 | 1.326 | 22.399 | 26.507 | 0.067a | 0.977a | 13.674a | 0.345 | 1.170 | 0.274 | |
| P值 | 0.267 | <0.001 | <0.001 | 0.967 | 0.613 | 0.001 | 0.709 | 0.312 | 0.745 | |
| 组别 | LDL-C ( | HDL-C ( | 25(OH)D3 ( | T值( | Z值( | PRGE ( | E2 ( | 睾酮( | FSH ( | LH ( |
| 骨质正常组 | 2.70±0.84 | 1.22±0.33 | 20.51±3.95 | -0.53±0.44 | 0.61±0.48 | 0.74±0.06 | 27.35±5.18 | 397.89±73.48 | 16.48±5.91 | 4.63±0.85 |
| 骨量减少组 | 2.75±0.71 | 1.46±0.38 | 17.90±5.58 | -1.64±0.32 | -0.51±0.36 | 0.76±0.14 | 24.33±2.59 | 357.45±78.86 | 15.32±6.32 | 4.69±0.87 |
| 骨质疏松组 | 2.92±0. 70 | 1.61±0.45 | 14.76±5.32 | -2.74±0.29 | -1.63±0.41 | 0.75±0.07 | 20.74±4.60 | 327.87±73.99 | 14.09±4.32 | 4.72±0.79 |
| F(χ2)值 | 1.426 | 29.587 | 19.630 | 27.630 | 25.220 | 0.719 | 42.676 | 26.635 | 1.484 | 0.217 |
| P值 | 0.242 | <0.001 | <0.001 | <0.001 | <0.001 | 0.488 | <0.001 | <0.001 | 0.229 | 0.805 |
| 项目 | β | SE | Wald χ2值 | P值 | OR值 | 95%CI |
|---|---|---|---|---|---|---|
| BMI | -0.378 | 0.188 | 4.054 | 0.044 | 0.685 | (0.474,0.990) |
| 腹围 | -0.342 | 0.116 | 8.726 | 0.003 | 0.710 | (0.566,0.891) |
| 每日活动量<1 h | 1.831 | 0.952 | 3.705 | 0.054 | 6.243 | (0.967,40.298) |
| HDL-C | 4.307 | 1.524 | 7.980 | 0.005 | 74.182 | (3.738,1 472.125) |
| 25(OH)D3 | -0.294 | 0.094 | 9.713 | 0.002 | 0.745 | (0.619,0.897) |
| E2 | -0.243 | 0.084 | 8.410 | 0.004 | 0.784 | (0.665,0.924) |
| 睾酮 | -0.012 | 0.006 | 3.756 | 0.053 | 0.988 | (0.976,1.000) |
Table 2 Multivariate Logistic regression analysis of factors associated with osteoporosis in elderly men
| 项目 | β | SE | Wald χ2值 | P值 | OR值 | 95%CI |
|---|---|---|---|---|---|---|
| BMI | -0.378 | 0.188 | 4.054 | 0.044 | 0.685 | (0.474,0.990) |
| 腹围 | -0.342 | 0.116 | 8.726 | 0.003 | 0.710 | (0.566,0.891) |
| 每日活动量<1 h | 1.831 | 0.952 | 3.705 | 0.054 | 6.243 | (0.967,40.298) |
| HDL-C | 4.307 | 1.524 | 7.980 | 0.005 | 74.182 | (3.738,1 472.125) |
| 25(OH)D3 | -0.294 | 0.094 | 9.713 | 0.002 | 0.745 | (0.619,0.897) |
| E2 | -0.243 | 0.084 | 8.410 | 0.004 | 0.784 | (0.665,0.924) |
| 睾酮 | -0.012 | 0.006 | 3.756 | 0.053 | 0.988 | (0.976,1.000) |
| 组别 | 例数 | 30 s曲臂次数(次) | 30 s连续坐椅站立次数(次) | 肩臂伸展距离(cm) | 坐位体前屈距离(cm) | 闭眼单足站立时间(s) | 2 min踏步走次数(次) | 起立走2.5 m所用时间(s) |
|---|---|---|---|---|---|---|---|---|
| 骨质正常组 | 76 | 17.34±8.69 | 14.57±2.41 | -11.22±4.04 | -3.71±1.21 | 4.03±0.86 | 86.54±14.65 | 8.10±1.97 |
| 骨量减少组 | 123 | 16.97±8.78 | 13.71±1.98 | -12.34±3.78 | -4.01±1.99 | 3.36±0.73 | 79.44±9.25 | 8.46±1.09 |
| 骨质疏松组 | 51 | 16.62±8.54 | 13.01±1.04 | -13.94±0.95 | -4.31±1.60 | 3.18±3.57 | 70.22±7.37 | 8.87±1.28 |
| F值 | 0.009 | 18.391 | 11.189 | 5.644 | 23.786 | 34.243 | 10.733 | |
| P值 | 0.991 | <0.001 | <0.001 | 0.004 | <0.001 | <0.001 | <0.001 |
Table 3 Comparison of physical fitness test results in elderly men with normal bone mineral density,osteopenia and osteoporosis
| 组别 | 例数 | 30 s曲臂次数(次) | 30 s连续坐椅站立次数(次) | 肩臂伸展距离(cm) | 坐位体前屈距离(cm) | 闭眼单足站立时间(s) | 2 min踏步走次数(次) | 起立走2.5 m所用时间(s) |
|---|---|---|---|---|---|---|---|---|
| 骨质正常组 | 76 | 17.34±8.69 | 14.57±2.41 | -11.22±4.04 | -3.71±1.21 | 4.03±0.86 | 86.54±14.65 | 8.10±1.97 |
| 骨量减少组 | 123 | 16.97±8.78 | 13.71±1.98 | -12.34±3.78 | -4.01±1.99 | 3.36±0.73 | 79.44±9.25 | 8.46±1.09 |
| 骨质疏松组 | 51 | 16.62±8.54 | 13.01±1.04 | -13.94±0.95 | -4.31±1.60 | 3.18±3.57 | 70.22±7.37 | 8.87±1.28 |
| F值 | 0.009 | 18.391 | 11.189 | 5.644 | 23.786 | 34.243 | 10.733 | |
| P值 | 0.991 | <0.001 | <0.001 | 0.004 | <0.001 | <0.001 | <0.001 |
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