Chinese General Practice ›› 2024, Vol. 27 ›› Issue (12): 1519-1524.DOI: 10.12114/j.issn.1007-9572.2023.0442
• Original Research • Previous Articles Next Articles
Received:
2023-05-12
Revised:
2023-09-20
Published:
2024-04-20
Online:
2024-01-23
Contact:
TIAN Limin
通讯作者:
田利民
作者简介:
基金资助:
Add to citation manager EndNote|Ris|BibTeX
URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2023.0442
作者 | 发表时间(年) | 研究设计 | 国家 | 样本量 | 男/女 | 年龄(岁) | NAFLD诊断方法 | 骨钙素检测方法 | BMI(kg/m2) | 血清骨钙素水平(ng/mL) | T2DM | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NAFLD组 | 非NAFLD组 | NAFLD组 | 非NAFLD组 | NAFLD组 | 非NAFLD组 | NAFLD组 | 非NAFLD组 | NAFLD组 | 非NAFLD组 | NAFLD组 | 非NAFLD组 | ||||||
YANG[ | 2016 | 横断面研究 | 韩国 | 249 | 610 | 249/0 | 610/0 | 45±6 | 45±7 | 超声 | 化学发光法 | 25.5±8.5 | 22.9±2.4 | 16.07± 4.42 | 17.36± 4.68 | 无 | 无 |
LIU[ | 2013 | 横断面研究 | 中国 | 364 | 1 319 | 364/0 | 1 319/0 | 40.52± 10.18 | 36.69± 11.37 | 超声 | 电化学发光免疫测定 | 26.25± 2.74 | 22.25± 2.67 | 20.81± 1.33 | 24.51± 1.38 | 无 | 无 |
LUO[ | 2015 | 横断面研究 | 中国 | 130 | 603 | 0/130 | 0/603 | 56.0± 5.0 | 56.2± 4.4 | 超声 | 电化学发光免疫测定 | 25.5± 2.8 | 22.1± 2.5 | 19.41± 5.71 | 22.66± 6.32 | 无 | 无 |
DENG[ | 2018 | 横断面研究 | 中国 | 232 | 308 | 232/0 | 308/0 | 50.52± 4.87 | 50.35± 5.18 | 超声 | 电化学发光免疫测定 | 26.33± 2.68 | 24.74± 2.71 | 20.23± 7.26 | 22.71± 7.67 | 无 | 无 |
DOU[ | 2013 | 横断面研究 | 中国 | 449 | 1 109 | 449/0 | 1 109/0 | 53.32± 8.3 | 54.3± 8.8 | 超声 | 电化学发光免疫测定 | 26.48± 3.05 | 23.43± 2.76 | 16.19± 4.94 | 17.13± 5.43 | 无 | 无 |
HU[ | 2016 | 横断面研究 | 中国 | 178 | 190 | 168/10 | 105/85 | 42.69± 9.52 | 37.69± 10.20 | 超声 | 放射免疫测定法 | 25.12± 2.28 | 23.68± 2.93 | 15.24± 2.50 | 17.28± 3.18 | 无 | 无 |
吴冰洁[ | 2014 | 横断面研究 | 中国 | 1 087 | 2 212 | 365/722 | 778 /1 434 | 61.30± 9.87 | 62.29± 11.50 | 超声 | 放射免疫测定法 | 25.81± 3.19 | 23.24± 2.89 | 18.92± 6.5 | 20.48± 7.12 | 无 | 无 |
杜婧[ | 2016 | 横断面研究 | 中国 | 44 | 130 | 34/10 | 89/41 | 64.5± 11.0 | 67.7± 9.8 | 超声 | 电化学发光免疫测定 | 26.5± 2.9 | 23.4± 2.7 | 18.18± 7.36 | 20.84± 7.95 | 无 | 无 |
王碧玉[ | 2014 | 病例对照研究 | 中国 | 64 | 64 | 38/26 | 35/29 | 56 | 52 | 超声 | 电化学发光免疫测定 | 1.89± 0.97 | 3.65± 1.55 | 无 | 无 | ||
母金娣[ | 2016 | 病例对照研究 | 中国 | 50 | 47 | 28/22 | 20/27 | 66.5± 5.8 | 65.9± 4.2 | 超声 | 电化学发光免疫测定 | 25.3± 2.6 | 23.6± 3.2 | 12.2± 4.7 | 18± 6.2 | 有 | 有 |
魏亚庆[ | 2017 | 病例对照研究 | 中国 | 54 | 50 | 54/0 | 50/0 | 53.81± 9.24 | 57.04± 10.82 | 超声 | 酶联免疫吸附测定 | 25.12± 2.784 | 23.28± 3.049 | 8.18± 4.649 | 13.04± 6.367 | 有 | 有 |
YILMAZ[ | 2011 | 病例对照研究 | 土耳其 | 99 | 75 | 50/49 | 37/38 | 48±8 | 48±7 | 活检 | 固相酶扩增免疫敏感性分析 | 30.6± 4.9 | 27.4± 4.3 | 2.26± 0.19 | 2.31± 0.15 | 有 | 无 |
XIA[ | 2021 | 队列研究 | 中国 | 679 | 1 376 | 279/400 | 578/798 | 超声 | 电化学发光免疫测定 | 无 | 无 |
Table 1 Characteristics of the included studies
作者 | 发表时间(年) | 研究设计 | 国家 | 样本量 | 男/女 | 年龄(岁) | NAFLD诊断方法 | 骨钙素检测方法 | BMI(kg/m2) | 血清骨钙素水平(ng/mL) | T2DM | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NAFLD组 | 非NAFLD组 | NAFLD组 | 非NAFLD组 | NAFLD组 | 非NAFLD组 | NAFLD组 | 非NAFLD组 | NAFLD组 | 非NAFLD组 | NAFLD组 | 非NAFLD组 | ||||||
YANG[ | 2016 | 横断面研究 | 韩国 | 249 | 610 | 249/0 | 610/0 | 45±6 | 45±7 | 超声 | 化学发光法 | 25.5±8.5 | 22.9±2.4 | 16.07± 4.42 | 17.36± 4.68 | 无 | 无 |
LIU[ | 2013 | 横断面研究 | 中国 | 364 | 1 319 | 364/0 | 1 319/0 | 40.52± 10.18 | 36.69± 11.37 | 超声 | 电化学发光免疫测定 | 26.25± 2.74 | 22.25± 2.67 | 20.81± 1.33 | 24.51± 1.38 | 无 | 无 |
LUO[ | 2015 | 横断面研究 | 中国 | 130 | 603 | 0/130 | 0/603 | 56.0± 5.0 | 56.2± 4.4 | 超声 | 电化学发光免疫测定 | 25.5± 2.8 | 22.1± 2.5 | 19.41± 5.71 | 22.66± 6.32 | 无 | 无 |
DENG[ | 2018 | 横断面研究 | 中国 | 232 | 308 | 232/0 | 308/0 | 50.52± 4.87 | 50.35± 5.18 | 超声 | 电化学发光免疫测定 | 26.33± 2.68 | 24.74± 2.71 | 20.23± 7.26 | 22.71± 7.67 | 无 | 无 |
DOU[ | 2013 | 横断面研究 | 中国 | 449 | 1 109 | 449/0 | 1 109/0 | 53.32± 8.3 | 54.3± 8.8 | 超声 | 电化学发光免疫测定 | 26.48± 3.05 | 23.43± 2.76 | 16.19± 4.94 | 17.13± 5.43 | 无 | 无 |
HU[ | 2016 | 横断面研究 | 中国 | 178 | 190 | 168/10 | 105/85 | 42.69± 9.52 | 37.69± 10.20 | 超声 | 放射免疫测定法 | 25.12± 2.28 | 23.68± 2.93 | 15.24± 2.50 | 17.28± 3.18 | 无 | 无 |
吴冰洁[ | 2014 | 横断面研究 | 中国 | 1 087 | 2 212 | 365/722 | 778 /1 434 | 61.30± 9.87 | 62.29± 11.50 | 超声 | 放射免疫测定法 | 25.81± 3.19 | 23.24± 2.89 | 18.92± 6.5 | 20.48± 7.12 | 无 | 无 |
杜婧[ | 2016 | 横断面研究 | 中国 | 44 | 130 | 34/10 | 89/41 | 64.5± 11.0 | 67.7± 9.8 | 超声 | 电化学发光免疫测定 | 26.5± 2.9 | 23.4± 2.7 | 18.18± 7.36 | 20.84± 7.95 | 无 | 无 |
王碧玉[ | 2014 | 病例对照研究 | 中国 | 64 | 64 | 38/26 | 35/29 | 56 | 52 | 超声 | 电化学发光免疫测定 | 1.89± 0.97 | 3.65± 1.55 | 无 | 无 | ||
母金娣[ | 2016 | 病例对照研究 | 中国 | 50 | 47 | 28/22 | 20/27 | 66.5± 5.8 | 65.9± 4.2 | 超声 | 电化学发光免疫测定 | 25.3± 2.6 | 23.6± 3.2 | 12.2± 4.7 | 18± 6.2 | 有 | 有 |
魏亚庆[ | 2017 | 病例对照研究 | 中国 | 54 | 50 | 54/0 | 50/0 | 53.81± 9.24 | 57.04± 10.82 | 超声 | 酶联免疫吸附测定 | 25.12± 2.784 | 23.28± 3.049 | 8.18± 4.649 | 13.04± 6.367 | 有 | 有 |
YILMAZ[ | 2011 | 病例对照研究 | 土耳其 | 99 | 75 | 50/49 | 37/38 | 48±8 | 48±7 | 活检 | 固相酶扩增免疫敏感性分析 | 30.6± 4.9 | 27.4± 4.3 | 2.26± 0.19 | 2.31± 0.15 | 有 | 无 |
XIA[ | 2021 | 队列研究 | 中国 | 679 | 1 376 | 279/400 | 578/798 | 超声 | 电化学发光免疫测定 | 无 | 无 |
第一作者 | 研究人群的选择 | 可比性 | 暴露或结果评价 | 总分 |
---|---|---|---|---|
YILMAZ[ | 3 | 1 | 2 | 6 |
YANG[ | 4 | 1 | 3 | 8 |
LIU[ | 4 | 1 | 3 | 8 |
LUO[ | 4 | 1 | 3 | 8 |
DENG[ | 3 | 1 | 2 | 6 |
DOU[ | 4 | 1 | 3 | 8 |
HU[ | 2 | 2 | 3 | 7 |
吴冰洁[ | 2 | 2 | 3 | 7 |
杜婧[ | 2 | 1 | 2 | 5 |
王碧玉[ | 3 | 1 | 2 | 6 |
母金娣[ | 2 | 1 | 2 | 5 |
魏亚庆[ | 3 | 1 | 2 | 6 |
XIA[ | 3 | 2 | 3 | 8 |
Table 2 Results of the quality assessment of included studies
第一作者 | 研究人群的选择 | 可比性 | 暴露或结果评价 | 总分 |
---|---|---|---|---|
YILMAZ[ | 3 | 1 | 2 | 6 |
YANG[ | 4 | 1 | 3 | 8 |
LIU[ | 4 | 1 | 3 | 8 |
LUO[ | 4 | 1 | 3 | 8 |
DENG[ | 3 | 1 | 2 | 6 |
DOU[ | 4 | 1 | 3 | 8 |
HU[ | 2 | 2 | 3 | 7 |
吴冰洁[ | 2 | 2 | 3 | 7 |
杜婧[ | 2 | 1 | 2 | 5 |
王碧玉[ | 3 | 1 | 2 | 6 |
母金娣[ | 2 | 1 | 2 | 5 |
魏亚庆[ | 3 | 1 | 2 | 6 |
XIA[ | 3 | 2 | 3 | 8 |
[1] |
|
[2] |
|
[3] |
|
[4] |
|
[5] |
|
[6] |
|
[7] |
|
[8] |
|
[9] |
|
[10] |
|
[11] |
|
[12] |
|
[13] |
|
[14] |
|
[15] |
|
[16] |
|
[17] |
|
[18] |
罗德惠,万翔,刘际明,等. 如何实现从样本量、中位数、极值或四分位数到均数与标准差的转换[J]. 中国循证医学杂志,2017,17(11):1350-1356. DOI:10.7507/1672-2531.201706060.
|
[19] |
|
[20] |
|
[21] |
|
[22] |
|
[23] |
|
[24] |
|
[25] |
|
[26] |
杜婧. 骨钙素与冠心病人群NAFLD的关系及其通过Nrf2及JNK通路改善小鼠NAFLD的机制研究[D]. 上海:上海交通大学,2016.
|
[27] |
母金娣. 老年2型糖尿病合并非酒精性脂肪性肝病与血清骨钙素水平的相关性研究[D]. 郑州:郑州大学,2016.
|
[28] |
王碧玉. 血清骨钙素及多项生化指标在非酒精性脂肪肝诊断中的临床意义[J]. 国际检验医学杂志,2014,35(10):1356-1357. DOI:10.3969/j.issn.1673-4130.2014.10.058.
|
[29] |
魏亚庆. 2型糖尿病合并非酒精性脂肪性肝病患者血清骨钙素水平的变化及相关影响因素[D]. 兰州:兰州大学,2017.
|
[30] |
吴冰洁. 上海长风社区中老年人群非酒精性脂肪性肝病与血清骨钙素、肝酶及性激素水平的关系研究[D]. 上海:复旦大学,2014.
|
[31] |
|
[32] |
|
[33] |
|
[34] |
|
[35] |
|
[36] |
|
[37] |
|
[38] |
|
[1] | LI Long, AN Xuemei, ZHANG Jie, HUANG Linyu, ZHANG Xingling. The Detection Rate of Postpartum Depression in Advanced Maternal Age in China: a Meta-analysis [J]. Chinese General Practice, 2024, 27(11): 1363-1369. |
[2] | HE Haiyang, YANG Jialing, LEI Xun. Prevalence and Influencing Factors of Osteoporosis in Postmenopausal Women: a Meta-analysis [J]. Chinese General Practice, 2024, 27(11): 1370-1379. |
[3] | HE Yufu, TONG Wenying, WANG Fang, LI Lixia, HE Junbing, SHAO Yiming. Effects of Pre-hospital Metformin Use on Clinical Outcomes in Patients with Diabetes and Sepsis [J]. Chinese General Practice, 2024, 27(09): 1034-1041. |
[4] | ZHAO Li, YANG Chunyan, ZUO Manyun, YANG Hongmei. Short-term Effects of Opportunistic Salpingectomy on Ovarian Reserve: a Meta-analysis of Randomized Controlled Trials Based on GRADE Evidence Grading System [J]. Chinese General Practice, 2024, 27(09): 1142-1148. |
[5] | YU Haibo, ZHANG Tianyu, LI Xin, ZHANG Jiajia, SHEN Man, ZHAN Xiaokai, TANG Ran, FAN Sibin, ZHAO Fengyi, HUANG Zhongxia. Efficacy and Safety of Dual-targeted Chimeric Antigen Receptor-T Cell Therapy in Patients with Refractory-relapsed Multiple Myeloma: a Meta-analysis [J]. Chinese General Practice, 2024, 27(08): 985-994. |
[6] | DONG Chenyang, LI Ran, LIU Ruoya, HUANG Zhiyang, YANG Yang. Effect of Exercise Interventions Based on Community Health Workers' Management on Type 2 Diabetes Mellitus: a Meta-analysis [J]. Chinese General Practice, 2024, 27(05): 577-588. |
[7] | FANG Yide, HU Hao, XU Jinhai, DING Xing, MA Qingshan, ZHANG Yayun, WANG Yanni, MO Wen. Efficacy and Safety of Manipulative Therapy for Frozen Shoulder: a Meta-analysis [J]. Chinese General Practice, 2024, 27(05): 628-636. |
[8] | LIU Peipei, ZHAO Zhenxue, ZHAO Chunshan. Sleep Time and Risk of Senile Dementia: a Dose-response Meta-analysis [J]. Chinese General Practice, 2024, 27(05): 622-627. |
[9] | XUE Chao, LI Juan, FANG Qian, YU Jie, HAO Mingqing. Prevalence and Trends for Post-stroke Fatigue in China: a Meta-analysis [J]. Chinese General Practice, 2024, 27(03): 364-374. |
[10] | DOU Ziyan, QIAN Wenhong, KONG Linrun, CHEN Ye, LI Mingliang, ZHANG Jingbo. Detection Rate of Non-alcoholic Fatty Liver Disease and Its Influencing Factors: Analysis Based on the Data of 320 000 Beijing Population [J]. Chinese General Practice, 2024, 27(02): 144-149. |
[11] | XIE Xuemei, GAO Jing, BAI Dingxi, LU Xianying, HE Jiali, LI Yue. Current Status of Polypharmacy in the Elderly and Its Influencing Factors: a Meta-analysis [J]. Chinese General Practice, 2023, 26(35): 4394-4403. |
[12] | WANG Yue, CHEN Qing, LIU Lurong. Detection Rate of Depression and Its Influencing Factors in Chinese Elderly: a Meta-analysis [J]. Chinese General Practice, 2023, 26(34): 4329-4335. |
[13] | WANG Zhe, DONG Zhihao, ZHENG Hao, KONG Wencheng, ZHANG Yukuan, ZHANG Qiuyue, HAN Jing. Construction of Optimized Treatment Plan of Acupuncture for Migraine Based on Entropy Weight-TOPSIS Method [J]. Chinese General Practice, 2023, 26(34): 4336-4342. |
[14] | JIAN Qiufeng, XU Ronghua, YAO Qian, ZHOU Yuanyuan. A Meta-analysis of the Prevalence and Influencing Factors of Post-stroke Cognitive Impairment in Chinese Elderly Patients [J]. Chinese General Practice, 2023, 26(32): 4070-4079. |
[15] | JIA Yu, ZHOU Zitong, CAO Xuehua, HU Wanqin, XIANG Feng, XIONG Langyu, WANG Xiaoxia. Incidence of Perimenopausal Syndrome in Chinese Women Aged 40 to 65 Years: a Meta-analysis [J]. Chinese General Practice, 2023, 26(32): 4080-4088. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||