Chinese General Practice ›› 2023, Vol. 26 ›› Issue (18): 2217-2222.DOI: 10.12114/j.issn.1007-9572.2022.0880
Special Issue: 呼吸疾病文章合集
• Original Research • Previous Articles Next Articles
Received:
2022-11-07
Revised:
2022-12-28
Published:
2023-06-20
Online:
2023-02-23
Contact:
WANG Haifeng
通讯作者:
王海峰
作者简介:
基金资助:
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2022.0880
观察指标 | 存活组(n=183) | 死亡组(n=57) | 检验统计量值 | P值 |
---|---|---|---|---|
年龄( | 64.3±16.1 | 69.5±11.7 | -2.669a | 0.009 |
性别(男/女) | 132/51 | 38/19 | 0.628b | 0.428 |
BMI〔M(P25,P75),kg/m2〕 | 22.5 (20.2,24.8) | 22.5 (20.2,25.0) | -0.120 | 0.905 |
临床体征 | ||||
体温〔M(P25,P75),℃〕 | 37.2 (36.7,38.1) | 37.3 (36.8,38.8) | -1.567 | 0.117 |
呼吸〔M(P25,P75),次/min〕 | 22.0 (20.0,29.0) | 25.0 (21.0,30.0) | -1.241 | 0.215 |
收缩压( | 126±22 | 126±23 | 0.025a | 0.980 |
合并症 | ||||
高血压〔n(%)〕 | 80(43.7) | 24(42.1) | 0.046b | 0.830 |
脑卒中〔n(%)〕 | 60(32.8) | 18(31.6) | 0.029b | 0.865 |
糖尿病〔n(%)〕 | 54(29.5) | 13(22.8) | 0.970b | 0.325 |
冠心病〔n(%)〕 | 60(32.8) | 14(24.6) | 1.379b | 0.240 |
心功能不全〔n(%)〕 | 29(15.8) | 8(14.0) | 0.109b | 0.741 |
慢性阻塞性肺疾病〔n(%)〕 | 27(14.8) | 8(14.0) | 0.018b | 0.893 |
实验室检查 | ||||
白细胞〔M(P25,P75),×109/L〕 | 10.1 (7.2,13.7) | 11.0 (6.9,17.0) | -1.237 | 0.216 |
血红蛋白( | 116.3±22.4 | 110.2±21.0 | 1.754a | 0.081 |
血小板计数〔M(P25,P75),×109/L〕 | 202.5 (131.8,264.8) | 155.5 (95.3,247.0) | -2.160 | 0.031 |
总胆红素〔M(P25,P75),μmol/L〕 | 12.4 (8.5,19.9) | 12.0 (7.9,20.8) | -0.332 | 0.740 |
肌酐〔M(P25,P75),μmol/L〕 | 66.0 (46.0,90.0) | 71.2 (50.5,92.3) | -0.558 | 0.577 |
尿素氮〔M(P25,P75),mmol/L〕 | 7.5 (5.0,12.4) | 9.1 (5.9,13.7) | -1.387 | 0.165 |
氧合指数〔M(P25,P75),mm Hg〕 | 187 (144,259) | 170 (121,246) | -1.710 | 0.087 |
Table 1 Comparisons of clinical characteristics between severe pneumonia patients in survival group and death group
观察指标 | 存活组(n=183) | 死亡组(n=57) | 检验统计量值 | P值 |
---|---|---|---|---|
年龄( | 64.3±16.1 | 69.5±11.7 | -2.669a | 0.009 |
性别(男/女) | 132/51 | 38/19 | 0.628b | 0.428 |
BMI〔M(P25,P75),kg/m2〕 | 22.5 (20.2,24.8) | 22.5 (20.2,25.0) | -0.120 | 0.905 |
临床体征 | ||||
体温〔M(P25,P75),℃〕 | 37.2 (36.7,38.1) | 37.3 (36.8,38.8) | -1.567 | 0.117 |
呼吸〔M(P25,P75),次/min〕 | 22.0 (20.0,29.0) | 25.0 (21.0,30.0) | -1.241 | 0.215 |
收缩压( | 126±22 | 126±23 | 0.025a | 0.980 |
合并症 | ||||
高血压〔n(%)〕 | 80(43.7) | 24(42.1) | 0.046b | 0.830 |
脑卒中〔n(%)〕 | 60(32.8) | 18(31.6) | 0.029b | 0.865 |
糖尿病〔n(%)〕 | 54(29.5) | 13(22.8) | 0.970b | 0.325 |
冠心病〔n(%)〕 | 60(32.8) | 14(24.6) | 1.379b | 0.240 |
心功能不全〔n(%)〕 | 29(15.8) | 8(14.0) | 0.109b | 0.741 |
慢性阻塞性肺疾病〔n(%)〕 | 27(14.8) | 8(14.0) | 0.018b | 0.893 |
实验室检查 | ||||
白细胞〔M(P25,P75),×109/L〕 | 10.1 (7.2,13.7) | 11.0 (6.9,17.0) | -1.237 | 0.216 |
血红蛋白( | 116.3±22.4 | 110.2±21.0 | 1.754a | 0.081 |
血小板计数〔M(P25,P75),×109/L〕 | 202.5 (131.8,264.8) | 155.5 (95.3,247.0) | -2.160 | 0.031 |
总胆红素〔M(P25,P75),μmol/L〕 | 12.4 (8.5,19.9) | 12.0 (7.9,20.8) | -0.332 | 0.740 |
肌酐〔M(P25,P75),μmol/L〕 | 66.0 (46.0,90.0) | 71.2 (50.5,92.3) | -0.558 | 0.577 |
尿素氮〔M(P25,P75),mmol/L〕 | 7.5 (5.0,12.4) | 9.1 (5.9,13.7) | -1.387 | 0.165 |
氧合指数〔M(P25,P75),mm Hg〕 | 187 (144,259) | 170 (121,246) | -1.710 | 0.087 |
风险评分 | 存活组(n=183) | 死亡组(n=57) | 检验统计量值 | P值 |
---|---|---|---|---|
SOFA评分〔M(P25,P75),分〕 | 4.0 (3.0,6.0) | 8.0 (4.5,10.0) | -5.536 | <0.001 |
SOFA评分分级〔n(%)〕a | 42.788b | <0.001 | ||
低危 | 125(68.3) | 17(29.8) | ||
中危 | 47(25.7) | 19(33.4) | ||
高危 | 11(6.0) | 21(36.8) | ||
CURB-65评分〔M(P25,P75),分〕 | 2.0 (1.0,3.0) | 2.0 (1.0,3.0) | -2.996 | 0.003 |
CURB-65评分〔n(%)〕 | 13.378b | 0.010 | ||
0分 | 22(12.0) | 1(1.8) | ||
1分 | 48(26.2) | 14(24.5) | ||
2分 | 66(36.1) | 16(28.1) | ||
3分 | 34(18.6) | 15(26.3) | ||
4分 | 13(7.1) | 11(19.3) | ||
PSI评分( | 109.1±37.5 | 127.4±39.8 | -3.174c | 0.002 |
PSI分级〔n(%)〕 | 9.845b | 0.043 | ||
Ⅰ级 | 1(0.5) | 0 | ||
Ⅱ级 | 24(13.1) | 5(8.8) | ||
Ⅲ级 | 37(20.2) | 4(7.0) | ||
Ⅳ级 | 68(37.2) | 21(36.8) | ||
Ⅴ级 | 53(29.0) | 27(47.4) |
Table 2 Comparisons of three risk score prediction models between severe pneumonia patients in survival group and death group
风险评分 | 存活组(n=183) | 死亡组(n=57) | 检验统计量值 | P值 |
---|---|---|---|---|
SOFA评分〔M(P25,P75),分〕 | 4.0 (3.0,6.0) | 8.0 (4.5,10.0) | -5.536 | <0.001 |
SOFA评分分级〔n(%)〕a | 42.788b | <0.001 | ||
低危 | 125(68.3) | 17(29.8) | ||
中危 | 47(25.7) | 19(33.4) | ||
高危 | 11(6.0) | 21(36.8) | ||
CURB-65评分〔M(P25,P75),分〕 | 2.0 (1.0,3.0) | 2.0 (1.0,3.0) | -2.996 | 0.003 |
CURB-65评分〔n(%)〕 | 13.378b | 0.010 | ||
0分 | 22(12.0) | 1(1.8) | ||
1分 | 48(26.2) | 14(24.5) | ||
2分 | 66(36.1) | 16(28.1) | ||
3分 | 34(18.6) | 15(26.3) | ||
4分 | 13(7.1) | 11(19.3) | ||
PSI评分( | 109.1±37.5 | 127.4±39.8 | -3.174c | 0.002 |
PSI分级〔n(%)〕 | 9.845b | 0.043 | ||
Ⅰ级 | 1(0.5) | 0 | ||
Ⅱ级 | 24(13.1) | 5(8.8) | ||
Ⅲ级 | 37(20.2) | 4(7.0) | ||
Ⅳ级 | 68(37.2) | 21(36.8) | ||
Ⅴ级 | 53(29.0) | 27(47.4) |
风险评分 | AIC | BIC |
---|---|---|
SOFA评分 | 226.79 | 233.76 |
CURB-65评分 | 256.69 | 263.66 |
PSI评分 | 259.10 | 266.06 |
Table 3 Values of AIC and BIC for different risk score prediction models
风险评分 | AIC | BIC |
---|---|---|
SOFA评分 | 226.79 | 233.76 |
CURB-65评分 | 256.69 | 263.66 |
PSI评分 | 259.10 | 266.06 |
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