Chinese General Practice ›› 2023, Vol. 26 ›› Issue (03): 287-292.DOI: 10.12114/j.issn.1007-9572.2022.0342
• Original Research • Previous Articles Next Articles
Received:
2022-05-17
Revised:
2022-06-12
Published:
2023-01-20
Online:
2022-09-15
Contact:
ZHANG Jing
About author:
通讯作者:
张静
作者简介:
基金资助:
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2022.0342
组别 | 例数 | 性别〔n(%)〕 | 年龄( | 文化程度〔n(%)〕 | 婚姻状况〔n(%)〕 | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
男 | 女 | 小学及以下 | 初中 | 中专或高中 | 高中以上 | 未婚 | 已婚 | 丧偶 | |||
非疲劳组 | 134 | 105(78.4) | 29(21.6) | 72±11 | 80(59.7) | 32(23.9) | 11(8.2) | 11(8.2) | 4(3.0) | 120(89.6) | 10(7.4) |
疲劳组 | 416 | 343(82.5) | 73(17.5) | 74±9 | 264(63.5) | 104(25.0) | 34(8.2) | 14(3.3) | 6(1.4) | 373(89.7) | 37(8.9) |
χ2(t)值 | 1.124 | -1.152a | 5.512 | 1.570 | |||||||
P值 | 0.289 | 0.250 | 0.138 | 0.456 | |||||||
组别 | 居住方式〔n(%)〕 | 合并症〔n(%)〕 | 吸烟史〔n(%)〕 | 家庭月收入〔n(%)〕 | |||||||
独居 | 与配偶同住 | 无 | 有 | 无 | 有 | ≤2 000元 | <5 000元 | ≥5 000元 | |||
非疲劳组 | 18(13.4) | 116(86.6) | 33(24.6) | 101(75.4) | 120(89.6) | 14(10.4) | 29(21.6) | 65(48.5) | 40(29.9) | ||
疲劳组 | 70(16.8) | 346(83.2) | 112(26.9) | 304(73.1) | 334(80.3) | 82(19.7) | 87(20.9) | 240(57.7) | 89(21.4) | ||
χ2(t)值 | 0.869 | 0.275 | 6.037 | 4.658 | |||||||
P值 | 0.351 | 0.600 | 0.014 | 0.097 |
Table 1 Comparison of general demographics between COPD patients with and without fatigue
组别 | 例数 | 性别〔n(%)〕 | 年龄( | 文化程度〔n(%)〕 | 婚姻状况〔n(%)〕 | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
男 | 女 | 小学及以下 | 初中 | 中专或高中 | 高中以上 | 未婚 | 已婚 | 丧偶 | |||
非疲劳组 | 134 | 105(78.4) | 29(21.6) | 72±11 | 80(59.7) | 32(23.9) | 11(8.2) | 11(8.2) | 4(3.0) | 120(89.6) | 10(7.4) |
疲劳组 | 416 | 343(82.5) | 73(17.5) | 74±9 | 264(63.5) | 104(25.0) | 34(8.2) | 14(3.3) | 6(1.4) | 373(89.7) | 37(8.9) |
χ2(t)值 | 1.124 | -1.152a | 5.512 | 1.570 | |||||||
P值 | 0.289 | 0.250 | 0.138 | 0.456 | |||||||
组别 | 居住方式〔n(%)〕 | 合并症〔n(%)〕 | 吸烟史〔n(%)〕 | 家庭月收入〔n(%)〕 | |||||||
独居 | 与配偶同住 | 无 | 有 | 无 | 有 | ≤2 000元 | <5 000元 | ≥5 000元 | |||
非疲劳组 | 18(13.4) | 116(86.6) | 33(24.6) | 101(75.4) | 120(89.6) | 14(10.4) | 29(21.6) | 65(48.5) | 40(29.9) | ||
疲劳组 | 70(16.8) | 346(83.2) | 112(26.9) | 304(73.1) | 334(80.3) | 82(19.7) | 87(20.9) | 240(57.7) | 89(21.4) | ||
χ2(t)值 | 0.869 | 0.275 | 6.037 | 4.658 | |||||||
P值 | 0.351 | 0.600 | 0.014 | 0.097 |
组别 | 例数 | 过去1年AECOPD发生次数 | BODE指数 | HADS-A评分 | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
<2次 | ≥2次 | 1级 | 2级 | 3级 | 4级 | 正常 | 轻度焦虑 | 中度焦虑 | 重度焦虑 | ||
非疲劳组 | 134 | 68(50.7) | 66(49.3) | 23(17.2) | 32(23.9) | 31(23.1) | 48(35.8) | 53(39.6) | 34(25.4) | 38(28.4) | 9(6.6) |
疲劳组 | 416 | 36(8.7) | 380(91.3) | 8(1.9) | 52(12.5) | 95(22.8) | 261(62.8) | 216(51.9) | 82(19.7) | 79(19.0) | 39(9.4) |
χ2(Z)值 | 117.112a | -6.719 | -2.007 | ||||||||
P值 | <0.010 | <0.010 | 0.045 | ||||||||
组别 | HADS-D评分 | CAT评分 | |||||||||
正常 | 轻度抑郁 | 中度抑郁 | 重度抑郁 | 影响轻微 | 影响中等 | 影响严重 | 影响非常严重 | ||||
非疲劳组 | 37(27.6) | 56(41.8) | 24(17.9) | 17(12.7) | 24(17.9) | 64(47.8) | 26(19.4) | 20(14.9) | |||
疲劳组 | 162(38.9) | 125(30.0) | 90(21.6) | 39(9.5) | 67(16.1) | 121(29.1) | 162(38.9) | 66(15.9) | |||
χ2(Z)值 | -1.579 | -2.782 | |||||||||
P值 | 0.114 | 0.005 |
Table 2 Clinical characteristics between COPD patients with and without fatigue
组别 | 例数 | 过去1年AECOPD发生次数 | BODE指数 | HADS-A评分 | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
<2次 | ≥2次 | 1级 | 2级 | 3级 | 4级 | 正常 | 轻度焦虑 | 中度焦虑 | 重度焦虑 | ||
非疲劳组 | 134 | 68(50.7) | 66(49.3) | 23(17.2) | 32(23.9) | 31(23.1) | 48(35.8) | 53(39.6) | 34(25.4) | 38(28.4) | 9(6.6) |
疲劳组 | 416 | 36(8.7) | 380(91.3) | 8(1.9) | 52(12.5) | 95(22.8) | 261(62.8) | 216(51.9) | 82(19.7) | 79(19.0) | 39(9.4) |
χ2(Z)值 | 117.112a | -6.719 | -2.007 | ||||||||
P值 | <0.010 | <0.010 | 0.045 | ||||||||
组别 | HADS-D评分 | CAT评分 | |||||||||
正常 | 轻度抑郁 | 中度抑郁 | 重度抑郁 | 影响轻微 | 影响中等 | 影响严重 | 影响非常严重 | ||||
非疲劳组 | 37(27.6) | 56(41.8) | 24(17.9) | 17(12.7) | 24(17.9) | 64(47.8) | 26(19.4) | 20(14.9) | |||
疲劳组 | 162(38.9) | 125(30.0) | 90(21.6) | 39(9.5) | 67(16.1) | 121(29.1) | 162(38.9) | 66(15.9) | |||
χ2(Z)值 | -1.579 | -2.782 | |||||||||
P值 | 0.114 | 0.005 |
自变量 | 赋值 |
---|---|
FS-14评分 | 非疲劳=0,疲劳=1 |
吸烟史 | 无=0,有=1 |
BODE指数 | 1级=0,2级=1,3级=2,4级=3 |
HADS-A评分 | 正常=0,轻度焦虑=1,中度焦虑=2,重度焦虑=3 |
CAT评分 | 影响轻微=0,影响中等=1,影响严重=2,影响非常严重=3 |
Table 3 Independent variable assignment of influencing factors of acute exacerbation in patients with COPD
自变量 | 赋值 |
---|---|
FS-14评分 | 非疲劳=0,疲劳=1 |
吸烟史 | 无=0,有=1 |
BODE指数 | 1级=0,2级=1,3级=2,4级=3 |
HADS-A评分 | 正常=0,轻度焦虑=1,中度焦虑=2,重度焦虑=3 |
CAT评分 | 影响轻微=0,影响中等=1,影响严重=2,影响非常严重=3 |
变量 | b | Waldχ2值 | P值 | HR(95%CI) | |
---|---|---|---|---|---|
FS-14评分(以非疲劳为参照) | |||||
疲劳 | 2.349 | 57.273 | <0.010 | 10.477(5.702,19.251) | |
吸烟史(以无为参照) | |||||
有 | 0.114 | 0.081 | 0.777 | 1.121(0.510,2.464) | |
BODE指数(以1级为参照) | |||||
2级 | 0.156 | 0.074 | 0.786 | 1.169(0.379,3.602) | |
3级 | 1.188 | 4.190 | 0.041 | 3.281(1.052,10.233) | |
4级 | 2.735 | 22.989 | <0.010 | 15.404(5.037,47.112) | |
HADS-A评分(以正常为参照) | |||||
轻度焦虑 | -0.196 | 0.285 | 0.593 | 0.822(0.401,1.686) | |
中度焦虑 | 1.880 | 17.622 | <0.010 | 6.551(2.724,15.757) | |
重度焦虑 | 3.609 | 10.637 | 0.001 | 36.914(4.221,322.856) | |
CAT评分(以影响轻微为参照) | |||||
影响中等 | 0.155 | 0.105 | 0.746 | 1.167(0.459,2.970) | |
影响严重 | 0.178 | 0.134 | 0.715 | 1.195(0.460,3.103) | |
影响非常严重 | -0.195 | 0.137 | 0.711 | 0.823(0.293,2.310) |
Table 4 Cox proportional hazard regression of factors influencing acute exacerbation in patients with COPD model analysis
变量 | b | Waldχ2值 | P值 | HR(95%CI) | |
---|---|---|---|---|---|
FS-14评分(以非疲劳为参照) | |||||
疲劳 | 2.349 | 57.273 | <0.010 | 10.477(5.702,19.251) | |
吸烟史(以无为参照) | |||||
有 | 0.114 | 0.081 | 0.777 | 1.121(0.510,2.464) | |
BODE指数(以1级为参照) | |||||
2级 | 0.156 | 0.074 | 0.786 | 1.169(0.379,3.602) | |
3级 | 1.188 | 4.190 | 0.041 | 3.281(1.052,10.233) | |
4级 | 2.735 | 22.989 | <0.010 | 15.404(5.037,47.112) | |
HADS-A评分(以正常为参照) | |||||
轻度焦虑 | -0.196 | 0.285 | 0.593 | 0.822(0.401,1.686) | |
中度焦虑 | 1.880 | 17.622 | <0.010 | 6.551(2.724,15.757) | |
重度焦虑 | 3.609 | 10.637 | 0.001 | 36.914(4.221,322.856) | |
CAT评分(以影响轻微为参照) | |||||
影响中等 | 0.155 | 0.105 | 0.746 | 1.167(0.459,2.970) | |
影响严重 | 0.178 | 0.134 | 0.715 | 1.195(0.460,3.103) | |
影响非常严重 | -0.195 | 0.137 | 0.711 | 0.823(0.293,2.310) |
[1] |
杨露露,曲木诗玮,司徒炫明,等. 慢性阻塞性肺疾病稳定期患者六分钟步行试验诱导的运动性低氧的预测方法研究[J]. 中国全科医学,2022,25(2):212-216. DOI:10.12114/j.issn.1007-9572.2021.01.038.
|
[2] |
|
[3] |
滕文哲,陈虎,石思瑶,等. 双水平正压通气治疗慢性阻塞性肺疾病急性加重期并发Ⅱ型呼吸衰竭效果的Meta分析与试验序贯分析[J]. 中国全科医学,2022,25(2):227-235. DOI:10.12114/j.issn.1007-9572.2021.01.224.
|
[4] |
|
[5] |
|
[6] |
|
[7] |
|
[8] |
GOLD. Global strategy for the diagnosis,management and prevention of chronic obstructive pulmonary disease[EB/OL].(2019-11-08)[2019-11-30].
|
[9] |
|
[10] |
张彩虹,阳晓丽,郭洪花,等. 自我管理项目对社区慢性阻塞性肺疾病患者焦虑抑郁及疲劳的影响[J]. 中国老年学杂志,2017,37(2):436-438. DOI:10.3969/j.issn.1005-9202.2017.02.080.
|
[11] |
|
[12] |
|
[13] |
吴婷,王宝燕,周海琴,等. BODE指数应用于等待肺移植终末期肺病病人的研究进展[J]. 护理研究,2019,33(17):2987-2990. DOI:10.12102/j.issn.1009-6493.2019.17.016.
|
[14] |
|
[15] |
李星茹,周甜甜,毕蒙蒙. 颅内动脉瘤患者焦虑及抑郁评估工具研究进展[J]. 实用临床医学,2020,21(10):97-101. DOI:10.13764/j.cnki.lcsy.2020.10.031.
|
[16] |
|
[17] |
宋伟伟,常双喜,禹彩霞,等. 慢性阻塞性肺疾病合并肺部感染者Th17/Treg、IL-17水平与肺功能及CAT评分的关系[J]. 中国老年学杂志,2022,42(8):1843-1846.
|
[18] |
|
[19] |
|
[20] |
|
[21] |
王明航,蔡坤坤,施丁莉,等. 基于回归分析法建立慢性阻塞性肺疾病急性加重风险预测模型与验证[J]. 中华危重病急救医学,2021,33(1):64-68. DOI:10.3760/cma.j.cn121430-20200720-00534.
|
[22] |
杨阳,杨雁. COPD缓解期患者血清PCT、IL-6、hs-CRP水平对急性加重的预测作用[J]. 广东医学,2017,38(10):1531-1533,1537. DOI:10.13820/j.cnki.gdyx.2017.10.008.
|
[23] |
|
[24] |
|
[25] |
|
[26] |
|
[27] |
|
[28] |
|
[29] |
Global Initiative for Chronic Obstructive Lung Disease. Global Strategy for the Diagnosis,Management and Prevention of Chronic Obstructive Pulmonary Disease(2022 Report)[EB/OL]. [2021-11-22].
|
[30] |
|
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