中国全科医学 ›› 2026, Vol. 29 ›› Issue (11): 1430-1433.DOI: 10.12114/j.issn.1007-9572.2024.0466

所属专题: 安宁疗护专题研究

• 论著 • 上一篇    

猴痘的临床特征与诊疗分析

吴延延, 邓前程, 罗丽敏, 朱伟芳*()   

  1. 310003 浙江省杭州市,浙江大学医学院附属第一医院皮肤科
  • 收稿日期:2024-06-10 修回日期:2024-10-10 出版日期:2026-04-15 发布日期:2024-11-06
  • 通讯作者: 朱伟芳

  • 作者贡献:

    吴延延负责文献收集、采集及论文起草;邓前程负责框架构建,论文核对;罗丽敏提出研究思路;朱伟芳负责最终版本修订,对论文整体负责。

  • 基金资助:
    国家青年科学基金项目(82103708); 浙江省基础公益研究项目(LGF21H90004)

Clinical Characteristics and Diagnosis and Treatment Analysis of Monkeypox

WU Yanyan, DENG Qiancheng, LUO Limin, ZHU Weifang*()   

  1. Department of Dermatology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
  • Received:2024-06-10 Revised:2024-10-10 Published:2026-04-15 Online:2024-11-06
  • Contact: ZHU Weifang

摘要: 2022-07-23和2024-08-14,世界卫生组织两次宣布猴痘(monkeypox)疫情构成国际关注的突发公共卫生事件(PHEIC)。2022年全球暴发的猴痘疫情中,男同性恋和双性恋男性占了绝大多数,但2024年疫情主要受累人群是妇女和15岁以下儿童及青少年。本文基于两次PHEIC,从猴痘的病原学、流行病学、临床表现、诊断、共病筛查、皮疹的鉴别诊断、治疗、预防等8个维度进行讨论,重点分析两次疫情的相同及不同点,尤其是针对皮疹变化展开叙述,从斑疹→丘疹→水疱→脓疱→结痂变化过程鉴别诊断,着重于皮肤科视角诊疗猴痘,旨在为其临床防治提供新的参考。

关键词: 猴痘, 皮肤病学, 疹, 诊断, 治疗

Abstract:

On July 23, 2022 and August 14, 2024, the World Health Organization declared the daily outbreak of monkeypox as a Public Health Emergency of International Concern (PHEIC) twice. While gay and bisexual men constituted the majority of cases in 2022, women and children under 15 years old were the primary victims of the 2024 outbreak. This paper examines the etiology, epidemiology, clinical manifestations, diagnosis, comorbidity screening, differential diagnosis, treatment and prevent of monkeypox in light of these two PHEICs. It particularly focuses on elucidating similarities and differences between the two outbreaks. Emphasizing changes in skin rash progression from macules to papules to vesicles to pustules to scabs is introduced for differential diagnosis purposes. The discussion also highlights dermatological perspectives on diagnosing and treating monkeypox with an aim to offer new insights for clinical prevention and treatment.

Key words: Monkeypox, Dermatology, Exanthema, Diagnosis, Treatment

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