饮食限制对机体免疫功能调节作用的研究进展

doi:10.12114/j.issn.1007-9572.2023.0659

中国全科医学 ›› 2025, Vol. 28 ›› Issue (32): 4102-4109.DOI: 10.12114/j.issn.1007-9572.2023.0659

饮食限制对机体免疫功能调节作用的研究进展

高佳新¹^,², 周蕊寒³, 王芳芳¹^,³, 庞日朝³, 张安仁²^,^*()

1．610075　四川省成都市，成都中医药大学养生康复学院
2．200434　上海市，同济大学医学院附属上海市第四人民医院康复医学科
3．610083　四川省成都市，中国人民解放军西部战区总医院康复医学科

收稿日期:2023-07-25 修回日期:2023-12-05 出版日期:2025-11-15 发布日期:2025-09-23
通讯作者: 张安仁
作者贡献：
高佳新负责研究的构思与设计、研究资料的收集与整理、论文撰写；周蕊寒、王芳芳、庞日朝负责论文修订；张安仁负责文章的质量控制及审校，对文章整体负责，监督管理。
基金资助:
国家自然科学基金面上项目(81973927)

Advances in Dietary Restriction on the Regulation of Organismal Immune Function

GAO Jiaxin¹^,², ZHOU Ruihan³, WANG Fangfang¹^,³, PANG Rizhao³, ZHANG Anren²^,^*()

1. School of Health and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China
2. Department of Rehabilitation Medicine, Shanghai Fourth People's Hospital Affiliated to Tongji University, Shanghai 200434, China
3. Department of Rehabilitation Medicine, the General Hospital of Western Theater Command PLA, Chengdu 610083, China

Received:2023-07-25 Revised:2023-12-05 Published:2025-11-15 Online:2025-09-23
Contact: ZHANG Anren

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摘要/Abstract

摘要： 营养状况可能影响免疫反应，饮食限制作为一种重要的饮食干预手段，已被证明可能会对免疫细胞的激活和效应功能的发挥起着重要的调节作用，并且参与着不同疾病的进展，因此，本综述总结了饮食限制对中性粒细胞、单核细胞等先天免疫细胞以及B细胞、T细胞等适应性免疫细胞功能状态的影响，并且还讨论了饮食限制作为一种治疗策略，在感染、慢性炎症以及癌症等疾病状态下对免疫功能的影响。

关键词: 禁食, 饮食限制, 免疫调节, 综述

Abstract:

Nutritional status may influence the immune response, and dietary restriction (DR) , as an important dietary intervention, has been shown to potentially play an important regulatory role in the activation and effector functioning of immune cells and is involved in the progression of different diseases. Therefore, this review summarises the effects of DR on the functional status of innate immune cells, such as neutrophils and monocytes, as well as adaptive immune cells, such as B cells and T cells, and also discusses the impact of DR as a therapeutic strategy on immune function in disease states such as infections, chronic inflammation, and cancer.

Key words: Fasting, Dietary restriction, Immunomodulation, Review

高佳新,周蕊寒,王芳芳,等. 饮食限制对机体免疫功能调节作用的研究进展[J]. 中国全科医学, 2025, 28(32): 4102-4109. DOI: 10.12114/j.issn.1007-9572.2023.0659.
GAO Jiaxin,ZHOU Ruihan,WANG Fangfang, et al. Advances in Dietary Restriction on the Regulation of Organismal Immune Function[J]. Chinese General Practice, 2025, 28(32): 4102-4109. DOI: 10.12114/j.issn.1007-9572.2023.0659.

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饮食限制对机体免疫功能调节作用的研究进展

Advances in Dietary Restriction on the Regulation of Organismal Immune Function

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