中国全科医学 ›› 2026, Vol. 29 ›› Issue (36): 5313-5325.DOI: 10.12114/j.issn.1007-9572.2026.0169

• 指南·共识·解读 •    

糖尿病患者相关认知功能障碍综合管理专家共识(2026版)

湖北省内分泌与代谢病临床医学研究中心, 武汉市预防医学会代谢健康与疾病防治专委会, 同济内分泌亚专科联盟, 彭婷1, 张彦超2, 刘旭3, 李婵4   

  1. 1.430000 湖北省武汉市,华中科技大学同济医学院附属同济医院内分泌科
    2.434000 湖北省荆州市中心医院内分泌科
    3.443003 湖北省宜昌市中心人民医院内分泌科
    4.445000 湖北省恩施市,湖北民族大学附属民大医院内分泌科
  • 收稿日期:2026-05-10 修回日期:2026-07-28 出版日期:2026-12-20 发布日期:2026-10-30
  • 执笔人:

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  • 基金资助:
    国家科技重大专项(2024ZD0523203); 华中科技大学同济医学院附属同济医院专项基金(2024D44)

Expert Consensus on Comprehensive Management of Diabetes-associated Cognitive Dysfunction (2026 Edition)

Hubei Provincial Clinical Medical Research Center for Endocrinology and Metabolic Diseases, Metabolic Health and Disease Prevention & Professional Committee, Wuhan Preventive Medicine Association, Tongji Hospital Endocrine Subspecialty Alliance, PENG Ting1, ZHANG Yanchao2, LIU Xu3, LI Chan4   

  1. 1. Department of Endocrinology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China
    2. Department of Endocrinology, Jingzhou Central Hospital, Jingzhou 434000, China
    3. Department of Endocrinology, Yichang Central People's Hospital, Yichang 443003, China
    4. Department of Endocrinology, Affiliated Minzu Hospital of Hubei Minzu University, Enshi 445000, China
  • Received:2026-05-10 Revised:2026-07-28 Published:2026-12-20 Online:2026-10-30
  • About author:

    Writers:

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摘要: 糖尿病相关认知功能障碍(DACD)是糖尿病常见慢性并发症之一,其发病率随糖尿病患病率上升及人口老龄化加剧而逐年增高。DACD显著降低患者生活质量,增加家庭照护负担及社会医疗支出,且与糖尿病患者自我管理依从性下降密切相关。现有DACD相关专家共识多侧重于临床诊断与治疗策略,而对患者日常自我管理、健康教育实施、认知功能训练及综合照护等核心环节的实践规范尚缺乏系统性指导。鉴于此,本工作组制订了《糖尿病患者相关认知功能障碍综合管理专家共识(2026版)》(以下简称《共识》)。《共识》的制订基于对国内外DACD相关指南、共识及原始研究的全面系统检索与循证整合,并通过开展2轮专家函询和1轮专家论证,采用改编版证据质量与推荐分级方法。最终形成的《共识》系统阐述了DACD的筛查评估方法及危险因素、分级管理、DACD专项管理(药物安全管理、血糖管理、生活方式干预)、认知干预与数字管理技术、中医适宜技术、DACD并发症管理(环境安全管理、行为与精神症状、游走与走失防范)以及DACD教育与支持,旨在为临床管理提供一套科学、全面、实用的实践参考依据。

关键词: 糖尿病, 认知功能障碍, 综合管理, 专家共识

Abstract:

Diabetes-associated cognitive dysfunction (DACD) is one of the common chronic complications of diabetes mellitus. Its incidence has been increasing annually alongside the rising prevalence of diabetes and the acceleration of population aging. DACD significantly impairs patients' quality of life, escalates family caregiving burden and societal healthcare expenditure, and is closely associated with diminished self-management adherence in diabetic patients. Existing expert consensuses on DACD predominantly focus on clinical diagnosis and therapeutic strategies, whereas systematic guidance regarding practical norms for core management components including patients' daily self-management, health education implementation, cognitive function training, and comprehensive care, remains insufficient. In view of this, the working group has formulated the Expert Consensus on Comprehensive Management of Diabetes-associated Cognitive Dysfunction (2026 Edition) (hereinafter referred to as the Consensus). The development of the Consensus was based on a comprehensive systematic retrieval and evidence-based integration of domestic and international DACD-related guidelines, consensuses, and original studies. Through two rounds of expert Delphi survey and one round of expert panel deliberation, an adapted version of the evidence quality and recommendation grading approach was employed. The finalized Consensus systematically elaborates on screening and assessment methods and risk factors for DACD, stratified management, DACD-specific management (medication safety management, glycemic management, lifestyle intervention), cognitive intervention and digital management technologies, appropriate traditional Chinese medicine techniques, DACD complication management (environmental safety management, behavioral and psychological symptoms, wandering and elopement prevention), as well as DACD education and support, aiming to provide a scientific, comprehensive, and practical reference for clinical management.

Key words: Diabetes mellitus, Cognitive dysfunction, Comprehensive management, Expert consensus

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