中国全科医学 ›› 2022, Vol. 25 ›› Issue (32): 4091-4098.DOI: 10.12114/j.issn.1007-9572.2022.0247

所属专题: 营养最新文章合集

• 知识窗 • 上一篇    

1991—2021年肝硬化营养研究热点及趋势可视化分析

陈冉1, 杨皓然2, 史会连1, 刘琼1, 汤婷1,*()   

  1. 1.210029 江苏省南京市,南京中医药大学附属医院 江苏省中医院感染科
    2.210046 江苏省南京市,南京中医药大学第一临床医学院
  • 收稿日期:2022-02-12 修回日期:2022-05-04 出版日期:2022-11-15 发布日期:2022-05-19
  • 通讯作者: 汤婷
  • 陈冉,杨皓然,史会连,等. 1991—2021年肝硬化营养研究热点及趋势可视化分析[J].中国全科医学,2022,25(32):4091-4098. [www.chinagp.net]
    作者贡献:陈冉进行文章的构思与设计,研究的实施、结果分析及解释,文章撰写及修订;杨皓然负责绘制图表及统计学处理;刘琼进行数据收集与整理;史会连、汤婷负责文章的最后修订、质量控制及审校,对文章整体负责。
  • 基金资助:
    国家自然科学基金青年科学基金(81903974)

Hotspots and Trends in Research on Nutrition in Cirrhosis from 1991 to 2021: a Visualized Review

CHEN Ran1, YANG Haoran2, SHI Huilian1, LIU Qiong1, TANG Ting1,*()   

  1. 1. Infectious Disease Department, Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, China
    2. First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210046, China
  • Received:2022-02-12 Revised:2022-05-04 Published:2022-11-15 Online:2022-05-19
  • Contact: TANG Ting
  • About author:
    CHEN R, YANG H R, SHI H L, et al. Hotspots and trends in research on nutrition in cirrhosis from 1991 to 2021: a visualized review [J]. Chinese General Practice, 2022, 25 (32) : 4091-4098.

摘要: 背景 肝硬化作为一种慢性消耗性疾病,对患者身体机能和营养状态的影响逐渐被学术界重视。定期回顾全球肝硬化营养领域研究热点,有助于推进我国肝硬化营养领域的创新和发展。 目的 通过文献计量学方法梳理与总结1991—2021年肝硬化营养领域相关研究并做可视化分析,探究该领域的发展情况、研究热点和发展趋势,以期为今后肝硬化营养相关研究提供参考与借鉴。 方法 以Web of Science数据库为来源,检索1991—2021年肝硬化营养研究的相关文献,运用CiteSpace知识图谱分析工具中合作网络和共现网络两个功能,对肝硬化营养研究的国家、机构、作者、关键词、突现关键词进行数据挖掘和可视化分析。 结果 1991—2021年肝硬化营养研究的文献共1 520篇,发文量呈波浪式上升,2020年及2021年发文量均突破100篇。美国是发文量(424篇)和中介中心性(0.32)均位居第一的国家。机构分布:梅奥诊所(美国)发文量(25篇)及中介中心性(0.08)位居第一,其次是岐阜大学(日本)、克利夫兰诊所(美国)、奥尔胡斯大学附属医院(丹麦)等。机构间形成以美国梅奥诊所、克利夫兰诊所为中心的美洲合作网络和以德国柏林查理特医科大学、瑞典卡罗斯卡学院为中心的欧洲合作网络。作者合作网络图谱共纳入891位作者,以TANDON P、KAWAGUCHI T为代表;高频关键词包括营养状况、肝移植、身体成分等,关键词突现分析中肌肉减少症的突现程度最高(突现强度26.170 9)。 结论 有关营养评估、肝移植和身体成分等内容的研究是肝硬化营养领域的研究热点,肝硬化伴肌肉减少症患者营养不良的病理生理机制和对此类患者的营养管理是今后研究的重点方向。

关键词: 肝硬化, 肌肉减少症, 营养不良, CiteSpace, Web of Science, 可视化分析

Abstract:

Background

Cirrhosis is a chronic consumption disease, whose impact on patients' physical function and nutritional status has been increasingly valued by the academic community. It is helpful to promote the innovation and development in nutrition for cirrhosis in China by reviewing the hotspots in global research on nutrition for cirrhosis periodically.

Objective

To perform a bibliometric and visualized review of the development, hotspots, and trends of studies on nutrition for cirrhosis published from 1991 to 2021, providing a reference for future studies related to nutrition in cirrhosis.

Methods

The studies about nutrition in cirrhosis published during 1991-2021 were searched from the database of Web of Science. Collaboration and co-occurrence network analyses supported by CiteSpace were used for data mining and visualization analysis of countries, institutions, authors, keywords, and burst keywords relevant to studies of nutrition in cirrhosis .

Results

A total of 1 520 studies were finally included, the yearly number of these studies demonstrated a wave-like growth during the period of 1991-2021, in particular, it exceeded 100 in 2020 and 2021. The U.S. ranked first in terms of the number of published studies (424) and intermediary centrality value (0.32). As for institutions, Mayo Clinic (the U.S.) ranked first in terms of the number of published studies (25) and intermediary centrality value (0.08), followed by Gifu University (Japan), Cleveland Clinic (the U.S.), and Aarhus University Hospital (Denmark). Inter-institutional collaborative networks were formed in the U.S., with Mayo Clinic and Cleveland Clinic, as the core, and in Europe, with Charite (Germany) and Karolinska Institute (Sweden) as the core. A total of 891 authors were included in the collaborative network, represented by TANDON P and KAWAGUCHI T. High-frequency keywords included nutritional status, liver transplantation, and body composition. Sarcopenia was the keyword with the strongest citation bursts (strength 26.170 9) .

Conclusion

Nutritional assessment, liver transplantation and body composition may be hot topics in research on nutrition in cirrhosis. And the pathophysiological mechanisms of malnutrition and nutritional management in patients with cirrhosis and sarcopenia may be foci of future research.

Key words: Liver cirrhosis, Sarcopenia, Malnutrition, CiteSpace, Web of Science, Visualization